Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Nephrology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Revelation Biosciences Starts its PRIME Phase 1b Clinical Study of Gemini in CKD Patients
Details : Gemini is the Company’s proprietary formulation of phosphorylated hexaacyl disaccharide, a TLR4 agonist. It is being evaluated for stage 3 and 4 chronic kidney disease (ckd).
Product Name : Gemini
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 21, 2025
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Nephrology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Nephrology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Revelation Biosciences Inc. Announces FDA Acceptance of Gemini IND
Details : Gemini is the Company’s proprietary formulation of phosphorylated hexaacyl disaccharide, a TLR4 agonist. It is being evaluated for acute kidney injury due to cardiac surgery.
Product Name : Undisclosed
Product Type : Large molecule
Upfront Cash : Not Applicable
December 02, 2024
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Nephrology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Nephrology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Revelation Biosciences Completes Dosing in Phase 1 Gemini Study
Details : Gemini is the Company’s proprietary formulation of phosphorylated hexaacyl disaccharide, a TLR4 agonist. It is being evaluated for acute kidney injury due to cardiac surgery.
Product Name : Gemini
Product Type : Large molecule
Upfront Cash : Not Applicable
June 13, 2024
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Nephrology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Roth Capital Partners
Deal Size : $6.2 million
Deal Type : Public Offering
Revelation Biosciences Inc. Announces Closing of $6.2 Million Public Offering
Details : The Company intends to use net proceeds to develop GEM-SSI, GEM-AKI, while REVTx-100 (phosphorylated hexaacyl disaccharide) is being developed for preventing and treating hospital-acquired infections.
Product Name : REVTx-100
Product Type : Large molecule
Upfront Cash : Undisclosed
February 05, 2024
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Roth Capital Partners
Deal Size : $6.2 million
Deal Type : Public Offering
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Roth Capital Partners
Deal Size : $6.2 million
Deal Type : Public Offering
Revelation Biosciences Inc. Announces Pricing of $6.2 Million Public Offering
Details : Proceeds will support the development of GEM-SSI, GEM-AKI, and GEM-CKD, with REVTx-100 being developed for the prevention and treatment of hospital-acquired infections.
Product Name : REVTx-100
Product Type : Large molecule
Upfront Cash : Undisclosed
February 01, 2024
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Roth Capital Partners
Deal Size : $6.2 million
Deal Type : Public Offering
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : REVTx-99b (Phosphorylated Hexaacyl Disaccharide) is proprietary intranasal formulation in development for allergic rhinitis symptoms, active ingredient has been shown in Phase 1 study to upregulate a protein, which competes for the native eotaxin recepto...
Product Name : REVTx-99a
Product Type : Large molecule
Upfront Cash : Not Applicable
June 13, 2022
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Efficacy data demonstrated that REVTx-99a did not meet its primary endpoint, area under the curve of viral load by quantitative RT-PCR from nasopharyngeal swabs, and the preliminary results suggest the difference between REVTx-99a and placebo was not sta...
Product Name : REVTx-99a
Product Type : Large molecule
Upfront Cash : Not Applicable
March 30, 2022
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : REVTx-99a activates a nonspecific immune response which differentiates it from most current treatments focused on a specific immune response, potentially enabling use of REVTx-99a for broader use across most infectious upper respiratory viruses.
Product Name : REVTx-99a
Product Type : Large molecule
Upfront Cash : Not Applicable
March 24, 2022
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Destum Partners
Deal Size : Undisclosed
Deal Type : Partnership
Details : Destum Partners Inc. to assist in finding an Ex-US development partner for its therapeutic product candidate REVTx-99, and development partner(s) worldwide for its therapeutic product candidate REVTx-200.
Product Name : REVTx-99
Product Type : Small molecule
Upfront Cash : Undisclosed
October 25, 2021
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Destum Partners
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : REVTx-99 is a proprietary intranasal drop formulation being developed for preventing and treating respiratory viral infections, like influenza and COVID-19. REVTx-99 acts by stimulating the innate immune system at the site of infection via an alternative...
Product Name : REVTx-99
Product Type : Large molecule
Upfront Cash : Not Applicable
October 04, 2021
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable