Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Nephrology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Revelation Biosciences Completes Dosing in Phase 1 Gemini Study
Details : Gemini is the Company’s proprietary formulation of phosphorylated hexaacyl disaccharide, a TLR4 agonist. It is being evaluated for acute kidney injury due to cardiac surgery.
Brand Name : Gemini
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 13, 2024
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Nephrology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Roth Capital Partners
Deal Size : $6.2 million
Deal Type : Public Offering
Revelation Biosciences Inc. Announces Closing of $6.2 Million Public Offering
Details : The Company intends to use net proceeds to develop GEM-SSI, GEM-AKI, while REVTx-100 (phosphorylated hexaacyl disaccharide) is being developed for preventing and treating hospital-acquired infections.
Brand Name : REVTx-100
Molecule Type : Large molecule
Upfront Cash : Undisclosed
February 05, 2024
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Roth Capital Partners
Deal Size : $6.2 million
Deal Type : Public Offering
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Roth Capital Partners
Deal Size : $6.2 million
Deal Type : Public Offering
Revelation Biosciences Inc. Announces Pricing of $6.2 Million Public Offering
Details : Proceeds will support the development of GEM-SSI, GEM-AKI, and GEM-CKD, with REVTx-100 being developed for the prevention and treatment of hospital-acquired infections.
Brand Name : REVTx-100
Molecule Type : Large molecule
Upfront Cash : Undisclosed
February 01, 2024
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Roth Capital Partners
Deal Size : $6.2 million
Deal Type : Public Offering
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : REVTx-99b (Phosphorylated Hexaacyl Disaccharide) is proprietary intranasal formulation in development for allergic rhinitis symptoms, active ingredient has been shown in Phase 1 study to upregulate a protein, which competes for the native eotaxin recepto...
Brand Name : REVTx-99a
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 13, 2022
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Efficacy data demonstrated that REVTx-99a did not meet its primary endpoint, area under the curve of viral load by quantitative RT-PCR from nasopharyngeal swabs, and the preliminary results suggest the difference between REVTx-99a and placebo was not sta...
Brand Name : REVTx-99a
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 30, 2022
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : REVTx-99a activates a nonspecific immune response which differentiates it from most current treatments focused on a specific immune response, potentially enabling use of REVTx-99a for broader use across most infectious upper respiratory viruses.
Brand Name : REVTx-99a
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 24, 2022
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Destum Partners
Deal Size : Undisclosed
Deal Type : Partnership
Details : Destum Partners Inc. to assist in finding an Ex-US development partner for its therapeutic product candidate REVTx-99, and development partner(s) worldwide for its therapeutic product candidate REVTx-200.
Brand Name : REVTx-99
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 25, 2021
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Destum Partners
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : REVTx-99 is a proprietary intranasal drop formulation being developed for preventing and treating respiratory viral infections, like influenza and COVID-19. REVTx-99 acts by stimulating the innate immune system at the site of infection via an alternative...
Brand Name : REVTx-99
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 04, 2021
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : REVTx-99 is a proprietary intranasal drop formulation in development for treatment of respiratory viral infection and is broadly applicable to most infectious viruses including Influenza A & B, parainfluenza, rhinovirus, RSV, SARS-CoV-2 and its variants.
Brand Name : REVTx-99
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 28, 2021
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Petra Acquisition
Deal Size : Undisclosed
Deal Type : Merger
Revelation Biosciences, Inc. to Become Publicly Traded Through a Merger with Petra Acquisition, Inc.
Details : The cash proceeds from the transaction are expected to fund the continued development of REVTx-99, Revelation’s lead therapeutic candidate.
Brand Name : REVTx‑99
Molecule Type : Large molecule
Upfront Cash : Undisclosed
August 30, 2021
Lead Product(s) : Phosphorylated Hexaacyl Disaccharide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Petra Acquisition
Deal Size : Undisclosed
Deal Type : Merger
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