Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Elarekibep
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : AstraZeneca
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : PRS-060/AZD-1402 (elarekibep) is Pieris’ lead respiratory Anticalin®-based drug candidate and an inhaled IL-4 receptor alpha inhibitor, under development for the treatment of asthma.
Product Name : PRS-060
Product Type : Peptide
Upfront Cash : Inapplicable
June 21, 2023
Lead Product(s) : Elarekibep
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : AstraZeneca
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Elarekibep
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : AstraZeneca
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : PRS-060 (elarekibep) blocks the IL-4Ralpha immunoreceptor, inhibiting small IL-4 and IL-13 proteins that drive a cascade of inflammatory responses in the lungs. It is being developed for the treatment of moderate-to-severe asthma.
Product Name : PRS-060
Product Type : Peptide
Upfront Cash : Inapplicable
April 05, 2023
Lead Product(s) : Elarekibep
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : AstraZeneca
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : PRS-342
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Boston Pharmaceuticals
Deal Size : $363.0 million
Deal Type : Licensing Agreement
Details : Under the terms of the agreement, Boston Pharmaceuticals has exclusively licensed worldwide rights to PRS-342. Boston Pharmaceuticals will be primarily responsible for development of the program, with both parties collaborating during the IND-enabling st...
Product Name : PRS-342
Product Type : Antibody
Upfront Cash : $10.0 million
April 26, 2021
Lead Product(s) : PRS-342
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Boston Pharmaceuticals
Deal Size : $363.0 million
Deal Type : Licensing Agreement
FDA Lifts Partial Clinical Hold Pieris Pharmaceuticals' Prs-343 Phase 1 Studies
Details : U.S. Food and Drug Administration (FDA) has lifted the previously announced partial clinical hold on the phase 1 studies of PRS-343. As previously guided, the Company intends to move into a proof-of-concept study of PRS-343 in gastroesophageal cancer.
Product Name : PRS-343
Product Type : Protein
Upfront Cash : Inapplicable
January 19, 2021
Lead Product(s) : Cinrebafusp Alpha,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Eli Lilly
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Lilly to supply Pieris with ramucirumab for the study as well as collaborate on data from the trial. Pieris is working towards initiation of a phase 2 single-arm combination study for the second-line treatment of HER2-positive gastric cancer later this y...
Product Name : PRS-343
Product Type : Protein
Upfront Cash : Undisclosed
October 08, 2020
Lead Product(s) : Cinrebafusp Alpha,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Eli Lilly
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Cinrebafusp Alpha,Atezolizumab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Company will present phase 1 dose-escalation monotherapy and combination with atezolizumab data for PRS-343, a 4-1BB/HER2 bispecific for the treatment of HER2-positive solid tumors, in an oral presentation session at the European Society for Medical Onco...
Product Name : PRS-343
Product Type : Protein
Upfront Cash : Inapplicable
July 23, 2020
Lead Product(s) : Cinrebafusp Alpha,Atezolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Cinrebafusp Alpha,Atezolizumab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Pieris Pharmaceuticals Announces Partial Clinical Hold On PRS-343
Details : The partial hold follows discussions with FDA regarding the Company's in-use study supporting the technical setup for clinical administration of PRS-343.
Product Name : PRS-343
Product Type : Protein
Upfront Cash : Inapplicable
July 20, 2020
Lead Product(s) : Cinrebafusp Alpha,Atezolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable