Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lexicon Reports Phase 2b PROGRESS Study Results on LX9211 for Neuropathy
Details : LX9211 (pilavapadin) is an oral, non-opioid investigational AAK1 inhibitor in adult patients with moderate to severe diabetic peripheral neuropathic pain.
Product Name : LX9211
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 03, 2025
Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lexicon to Announce Phase 2b PROGRESS Topline for Pilavapadin in DPN Pain
Details : LX9211 (pilavapadin) is an oral, non-opioid investigational AAK1 inhibitor in adult patients with moderate to severe diabetic peripheral neuropathic pain.
Product Name : LX9211
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 02, 2025
Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lexicon Concludes Enrollment for Phase 2B PROGRESS Study in Diabetic Pain
Details : LX9211 is an AAK-1 Inhibitor small molecule drug. It is being investigated for the treatment of diabetic peripheral neuropathic pain.
Product Name : LX9211
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 26, 2024
Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Jefferies
Deal Size : $250.0 million
Deal Type : Private Placement
Lexicon Announces Oversubscribed $250 Million Private Placement of Equity Securities
Details : Lexicon plans to use proceeds for continued research and commercialization of LX9211, an orally delivered treatment for diabetic peripheral neuropathic pain.
Product Name : LX9211
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
November 03, 2024
Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Jefferies
Deal Size : $250.0 million
Deal Type : Private Placement
Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lexicon Completes Screening for Phase 2B LX9211 Study in DPNP
Details : LX9211 is an orally-delivered small molecule compound, works by inhibiting AAK1, it is being developed as a treatment for diabetic peripheral neuropathic pain.
Product Name : LX9211
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 22, 2024
Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : LX9211 is an AAK-1 Inhibitor small molecule drug taken orally as a tablet, it is being investigated for the treatment for diabetic peripheral neuropathic pain.
Product Name : LX9211
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 30, 2023
Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lexicon Announces Planned Advancement of LX9211 Into Late-Stage Development
Details : LX9211 is a potent, orally delivered, selective, investigational small molecule inhibitor of adaptor-associated kinase 1 (AAK1), which is investigated for the treatment of diabetic peripheral neuropathic pain.
Product Name : LX9211
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 23, 2023
Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : LX9211 is a potent, orally delivered, selective small molecule inhibitor of adaptor-associated kinase 1 (AAK1). Preclinical studies of LX9211 demonstrated CNS penetration and reduction in pain behavior in models of neuropathic pain without affecting opia...
Product Name : LX9211
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 21, 2022
Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : LX9211 is a potent, orally delivered, selective small molecule inhibitor of adaptor-associated kinase 1 (AAK1). LX9211 demonstrated central nervous system penetration and reduction in pain behavior in models of neuropathic pain without affecting opiate p...
Product Name : LX9211
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 14, 2022
Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Bristol Myers Squibb
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : LX9211 is a potent, orally delivered, small molecule inhibitor of adaptor-associated kinase 1. Preclinical studies of LX9211 demonstrated central nervous system penetration and reduction in pain behavior in models of neuropathic pain without affecting op...
Product Name : LX9211
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 24, 2022
Lead Product(s) : Pilavapadin
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Bristol Myers Squibb
Deal Size : Inapplicable
Deal Type : Inapplicable