Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Pirtobrutinib
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Jaypirca (pirtobrutinib) is an oral small molecule, BTK inhibitor which is under phase 3 clinical development for the treatment of chronic/small lymphocytic leukemia & mantle cell lymphoma.
Brand Name : Jaypirca
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 11, 2023
Lead Product(s) : Pirtobrutinib
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Pirtobrutinib
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Jaypirca® (pirtobrutinib) is a non-covalent (reversible) BTK inhibitor. It is approved for the treatment of adult patients with chronic lymphocytic leukemia or small lymphocytic lymphoma.
Brand Name : Jaypirca
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 01, 2023
Lead Product(s) : Pirtobrutinib
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Pirtobrutinib
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Jaypirca (pirtobrutinib) is a small molecule and a highly selective non-covalent inhibitor of Bruton’s tyrosine kinase (BTK). Its high selectivity has been associated with lower discontinuation rates due to adverse events and a lower incidence of atria...
Brand Name : Jaypirca
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 01, 2023
Lead Product(s) : Pirtobrutinib
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Pirtobrutinib
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Jaypirca (pirtobrutinib) is a highly selective, reversible inhibitor of the enzyme BTK. BTK is a validated molecular target found across numerous B-cell leukemias and lymphomas including mantle cell lymphoma.
Brand Name : Jaypirca
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 27, 2023
Lead Product(s) : Pirtobrutinib
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Pirtobrutinib,Venetoclax,Rituximab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Pirtobrutinib (LOXO-305), is an investigational, highly selective, reversible (non-covalent) inhibitor of Bruton's tyrosine kinase (BTK). Pirtobrutinib was developed to reversibly bind BTK, deliver consistently high target coverage regardless of BTK turn...
Brand Name : LOXO-305
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 12, 2022
Lead Product(s) : Pirtobrutinib,Venetoclax,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Pirtobrutinib
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Pirtobrutinib (LOXO-305), is an investigational, highly selective, reversible (non-covalent) Bruton's tyrosine kinase (BTK) inhibitor to treat chronic lymphocytic leukemia.
Brand Name : LOXO-305
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 03, 2022
Lead Product(s) : Pirtobrutinib
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Pirtobrutinib,Venetoclax,Rituximab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lilly Announces Details of Presentations at 2022 American Association for Cancer Research (AACR)
Details : Data will be presented from BRUIN Phase 1b study of pirtobrutinib, an investigational, highly selective, non-covalent (reversible) BTK inhibitor, in combination with venetoclax, a CDK4/6 inhibitor with and without rituximab in relapsed/refractory chronic...
Brand Name : LOXO-305
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 08, 2022
Lead Product(s) : Pirtobrutinib,Venetoclax,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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