Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : PL8177
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Palatin Reports Positive Phase 2 Results Of PL8177 for Ulcerative Colitis
Details : PL8177 is a selective melanocortin-1 receptor (MC1R) agonist, which is currently being evaluated in patients with active ulcerative colitis (UC).
Product Name : PL8177
Product Type : Peptide
Upfront Cash : Inapplicable
March 28, 2025
Lead Product(s) : PL8177
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : PL8177
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Palatin Completes Enrollment for PL8177 Phase 2 Ulcerative Colitis Study
Details : PL8177 is a potent, selective agonist at the human melanocortin-1 receptor. It is being evaluated for the treatment of ulcerative colitis in adult.
Product Name : PL8177
Product Type : Peptide
Upfront Cash : Inapplicable
November 25, 2024
Lead Product(s) : PL8177
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : PL8177
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : PL8177 is a synthetic cyclic heptapeptide with efficacy in multiple animal inflammatory bowel disease models. PL8177 is a potent, selective agonist at the human melanocortin receptor-1, with sub-nanomolar affinity binding and EC50 functional values.
Product Name : PL8177
Product Type : Peptide
Upfront Cash : Inapplicable
October 01, 2023
Lead Product(s) : PL8177
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : PL8177
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Palatin Presents PL8177 Data at American College of Gastroenterology Annual Meeting
Details : PL8177 is a potent, selective agonist oral formulations at the human melanocortin receptor-1 (MC1r), with sub-nanomolar affinity binding and EC50 functional values.
Product Name : PL8177
Product Type : Peptide
Upfront Cash : Inapplicable
October 24, 2022
Lead Product(s) : PL8177
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : PL8177
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : PL8177 is a synthetic cyclic heptapeptide with demonstrated efficacy in multiple animal inflammatory bowel disease models. PL8177 is a potent, selective agonist at the human melanocortin receptor-1 (MC1r), with sub-nanomolar affinity binding and EC50 fun...
Product Name : PL8177
Product Type : Peptide
Upfront Cash : Inapplicable
August 09, 2022
Lead Product(s) : PL8177
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : PL8177
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : This decision was based on positive results in preclinical multiple inflammatory disease models and a lung injury model, which showed the ability of PL8177 to reduce inflammation, protect lung tissue and reduce lung fibrosis.
Product Name : PL8177
Product Type : Peptide
Upfront Cash : Inapplicable
June 23, 2020
Lead Product(s) : PL8177
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable