Lead Product(s) : Plasminogen
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Approved
Sponsor : Kedrion
Deal Size : $17.0 million
Deal Type : Acquisition
Kedrion Biopharma Grows in North America As it Completes Acquisition of Prometic
Details : With the acquisition of Prometic, Kedrion has finalized a series of transactions with the announcement that it was acquiring the plasma purification plant at Laval in Québec, and the license to distribute the new product called Ryplazim in the United St...
Brand Name : Ryplazim
Molecule Type : Large molecule
Upfront Cash : Undisclosed
October 18, 2021
Lead Product(s) : Plasminogen
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Approved
Sponsor : Kedrion
Deal Size : $17.0 million
Deal Type : Acquisition
Lead Product(s) : Plasminogen
Therapeutic Area : Genetic Disease
Study Phase : Approved
Sponsor : Kedrion
Deal Size : $17.0 million
Deal Type : Agreement
Details : This acquisition would include the Ryplazim® (plasminogen, human-tvmh) (“Ryplazim®”) business operated through its subsidiaries, Prometic Bioproduction Inc., the Company’s plasma-derived therapeutics manufacturing facility (“PBP”), and Promet...
Brand Name : Ryplazim
Molecule Type : Large molecule
Upfront Cash : Undisclosed
June 23, 2021
Lead Product(s) : Plasminogen
Therapeutic Area : Genetic Disease
Highest Development Status : Approved
Sponsor : Kedrion
Deal Size : $17.0 million
Deal Type : Agreement
Lead Product(s) : Plasminogen
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Kedrion
Deal Size : $22.0 million
Deal Type : Acquisition
Details : Kedrion will enter into an option agreement with Liminal BioSciences to acquire the remainder of the company’s plasma-derived business, as well as Plasminogen business operated through its subsidiaries including Prometic Biotherapeutics which holds the...
Brand Name : Ryplazim
Molecule Type : Large molecule
Upfront Cash : Undisclosed
May 17, 2021
Lead Product(s) : Plasminogen
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Kedrion
Deal Size : $22.0 million
Deal Type : Acquisition
Lead Product(s) : Plasminogen
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Approved
Sponsor : Kedrion
Deal Size : $17.0 million
Deal Type : Acquisition
Kedrion enters into Agreement with Liminal BioSciences
Details : According to terms and conditions, the Option would grant Kedrion the right to acquire all of the shares of PBP and PBT and would entitle Liminal BioSciences to receive up to seventy percent of the net proceeds, if granted, associated with a potential FD...
Brand Name : Ryplazim
Molecule Type : Large molecule
Upfront Cash : Undisclosed
May 17, 2021
Lead Product(s) : Plasminogen
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Approved
Sponsor : Kedrion
Deal Size : $17.0 million
Deal Type : Acquisition
Lead Product(s) : Plasminogen
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Two posters were presented that highlighted individual case histories of patients with C-PLGD treated with the investigational intravenous Ryplazim® (plasminogen) in compassionate use and expanded access cases.
Brand Name : Ryplazim
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 07, 2020
Lead Product(s) : Plasminogen
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Plasminogen
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Liminal BioSciences Announces FDA Extension of Review Period for Ryplazim®(Plasminogen) BLA
Details : The BLA resubmission for Ryplazim® was supported by data from a Phase 2/3 clinical trial, which evaluated 15 patients, both pediatric and adults, with C-PLGD over 48 weeks of therapy with Ryplazim®.
Brand Name : Ryplazim
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 08, 2020
Lead Product(s) : Plasminogen
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Plasminogen
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Two abstracts related to the Company’s clinical development activities of Ryplazim® for the treatment of Congenital Plasminogen Deficiency will be presented at the 62nd American Society of Hematology Annual Meeting and Exposition scheduled to take pla...
Brand Name : Ryplazim
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 05, 2020
Lead Product(s) : Plasminogen
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Plasminogen
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Liminal BioSciences Provides Update on Progress on BLA for Ryplazim®(plasminogen)
Details : The BLA resubmission for Ryplazim® is supported by data from a Phase 2/3 clinical study which evaluated 15 patients, both pediatric and adults, with congenital plasminogen deficiency over 48 weeks of therapy with Ryplazim®.
Brand Name : Ryplazim
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 21, 2020
Lead Product(s) : Plasminogen
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Plasminogen
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : In a pivotal phase 2/3 clinical trial for the treatment of C-PLGD, all of the patients treated with Ryplazim® achieved at least the targeted increase from baseline in their individual trough plasminogen activity levels through 12 weeks of therapy.
Brand Name : Ryplazim
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 08, 2020
Lead Product(s) : Plasminogen
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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