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Biopharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Radiolabelled Compounds","year":"2021","type":"Inapplicable","leadProduct":"177-Lu PNT2004","moa":"Undisclosed","graph1":"Oncology","graph2":"IND Enabling","graph3":"Point Biopharma","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Point Biopharma \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"Point Biopharma \/ Inapplicable"},{"orgOrder":0,"company":"Point Biopharma","sponsor":"Belgian Nuclear Research Center","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Radiolabelled Compounds","year":"2021","type":"Licensing Agreement","leadProduct":"177-Lu","moa":"||Beta-radiation","graph1":"Oncology","graph2":"Phase III","graph3":"Point Biopharma","amount2":0,"highestDevelopmentShortName":"Ph 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Lilly","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Radiolabelled Compounds","year":"2023","type":"Acquisition","leadProduct":"177-Lu Zadavotide Guraxetan","moa":"Beta-radiation","graph1":"Oncology","graph2":"Phase III","graph3":"Point Biopharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Point Biopharma \/ Eli Lilly","highestDevelopmentStatusID":"10","companyTruncated":"Point Biopharma \/ Eli Lilly"},{"orgOrder":0,"company":"Point Biopharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Radiolabelled Compounds","year":"2022","type":"Inapplicable","leadProduct":"177-Lu PSMA-I&T","moa":"PSMA","graph1":"Oncology","graph2":"Phase III","graph3":"Point Biopharma","amount2":0,"highestDevelopmentShortName":"Ph 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Biopharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Radiolabelled Compounds","year":"2022","type":"Inapplicable","leadProduct":"177-Lu Zadavotide Guraxetan","moa":"Beta-radiation","graph1":"Oncology","graph2":"Phase III","graph3":"Point Biopharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Point Biopharma \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Point Biopharma \/ Inapplicable"},{"orgOrder":0,"company":"Point Biopharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Radiolabelled Compounds","year":"2023","type":"Inapplicable","leadProduct":"177-Lu Zadavotide Guraxetan","moa":"Beta-radiation","graph1":"Oncology","graph2":"Phase III","graph3":"Point Biopharma","amount2":0,"highestDevelopmentShortName":"Ph 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Compounds","year":"2021","type":"Agreement","leadProduct":"225-Ac","moa":"||Alpha-radiation","graph1":"Oncology","graph2":"Preclinical","graph3":"Point Biopharma","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Point Biopharma \/ Ionetix","highestDevelopmentStatusID":"4","companyTruncated":"Point Biopharma \/ Ionetix"}]

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                          01

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : Through the acquisition, Lilly expands its oncology capabilities into next-generation radioligand therapies by including PNT2002 (177Lu-PNT2002), a PSMA targeted radioligand therapy in development for patients with metastatic castration-resistant prostat...

                          Product Name : 177-Lu PNT2002

                          Product Type : Radiolabelled Compounds

                          Upfront Cash : $1,400.0 million

                          December 27, 2023

                          Lead Product(s) : 177-Lu PNT2002

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Eli Lilly

                          Deal Size : $1,400.0 million

                          Deal Type : Acquisition

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                          02

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : PNT2002 (Lu-177-PSMA-I&T) is a PSMA-Targeted therapy for metastatic castration-resistant prostate cancer (mCRPC). PNT2002 combines a PSMA-targeted ligand, PSMA-I&T, with the beta-emitting radioisotope lutetium-177.

                          Product Name : PNT2002

                          Product Type : Radiolabelled Compounds

                          Upfront Cash : Inapplicable

                          December 01, 2023

                          Lead Product(s) : 177-Lu Zadavotide Guraxetan

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : PNT2002 (Lu-177-PSMA-I&T) is a PSMA-Targeted therapy for metastatic castration-resistant prostate cancer (mCRPC). PNT2002 combines a PSMA-targeted ligand, PSMA-I&T, with the beta-emitting radioisotope lutetium-177.

                          Product Name : 177-Lu PNT2002

                          Product Type : Radiolabelled Compounds

                          Upfront Cash : Inapplicable

                          April 24, 2023

                          Lead Product(s) : 177-Lu PNT2002

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Lantheus Holding

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : Through the acquisition, Lilly expands its oncology capabilities into next-generation radioligand therapies by including PNT2002 (177Lu-PNT2002), a PSMA targeted radioligand therapy in development for patients with metastatic castration-resistant prostat...

                          Product Name : PNT2002

                          Product Type : Radiolabelled Compounds

                          Upfront Cash : $1,400.0 million

                          March 10, 2023

                          Lead Product(s) : 177-Lu Zadavotide Guraxetan

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Eli Lilly

                          Deal Size : $1,400.0 million

                          Deal Type : Acquisition

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                          05

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : PNT2002 (Lu-177-PSMA-I&T) is a PSMA-Targeted therapy for metastatic castration-resistant prostate cancer (mCRPC). PNT2002 combines a PSMA-targeted ligand, PSMA-I&T, with the beta-emitting radioisotope lutetium-177.

                          Product Name : PNT2002

                          Product Type : Radiolabelled Compounds

                          Upfront Cash : $260.0 million

                          December 20, 2022

                          Lead Product(s) : 177-Lu Zadavotide Guraxetan

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Lantheus Holding

                          Deal Size : $2,115.0 million

                          Deal Type : Agreement

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                          06

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : The study found that combination treatment with PNT2004 (177Lu-PNT6555) and anti-PD-1 resulted in a significant survival benefit, as compared to either treatment independently.

                          Product Name : 177-Lu PNT6555

                          Product Type : Radiolabelled Compounds

                          Upfront Cash : Inapplicable

                          November 29, 2022

                          Lead Product(s) : 177-Lu PNT6555,Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : Lu-177-PSMA-I&T (Lu-177-PNT2002) is a PSMA-Targeted therapy for mCRPC. PSMA is overexpressed in the vast majority of prostate cancers, but very limited to normal tissues. PNT2002 combines a PSMA-targeted ligand, PSMA-I&T, with the beta-emitting radioisot...

                          Product Name : 177-Lu PNT2002

                          Product Type : Radiolabelled Compounds

                          Upfront Cash : $260.0 million

                          November 14, 2022

                          Lead Product(s) : 177-Lu PNT2002

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Lantheus Holding

                          Deal Size : $2,115.0 million

                          Deal Type : Collaboration

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                          08

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : The clinical candidate in the PNT2004 program, PNT6555, is a D-ala-boroPro based FAP targeting radioligand. In animal studies, PNT6555 has successfully delivered large doses of radiation to tumors with limited uptake observed in non-target tissues.

                          Product Name : 177-Lu PNT6555

                          Product Type : Radiolabelled Compounds

                          Upfront Cash : Inapplicable

                          November 04, 2022

                          Lead Product(s) : 177-Lu PNT6555

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : PNT2001 displays enhanced internalization, biodistribution, and pre-clinical efficacy in multiple tumor models, making it a prime candidate for the delivery of actinium-225.

                          Product Name : PNT2001

                          Product Type : Radiolabelled Compounds

                          Upfront Cash : Inapplicable

                          October 17, 2022

                          Lead Product(s) : PNT2001

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : POINT intends to use the net proceeds from the proposed offering, to fund clinical and preclinical research and development programs including PNT2002 (Lu-177-PSMA-I&T), pre-commercialization activities, and for working capital and other general corporat...

                          Product Name : PNT2002

                          Product Type : Radiolabelled Compounds

                          Upfront Cash : Undisclosed

                          September 16, 2022

                          Lead Product(s) : 177-Lu Zadavotide Guraxetan

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Piper Sandler

                          Deal Size : $13.9 million

                          Deal Type : Public Offering

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