Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : PTG-007,Rituximab
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
PolTREG Launches Phase 2 Cell Therapy Trial in Children with Presymptomatic Diabetes
Details : PTG-007 is an Advanced Therapy Medicinal Product (ATMP), which serves as a platform to develop therapies for a wide range of autoimmune diseases, including presymptomatic type-1 diabetes (T1D).
Product Name : PTG-007
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
October 24, 2024
Lead Product(s) : PTG-007,Rituximab
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
PolTREG Starts Preclinical CAR-Treg Development for Neuroinflammatory Autoimmune Diseases
Details : PolTREG’s CAR-Treg cells will be developed using the same technology platform as its lead product PTG-007, a polyclonal Treg cell therapy for treating neuroinflammatory autoimmune diseases.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
September 26, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : PTG-007,Rituximab
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
PolTREG Cell Therapy Shows Long-Term Remission in Type 1 Diabetes Patients
Details : PTG-007, an autologous Treg treatment, resulted in clinical remission for up to 12 years in patients with type-1 diabetes (T1D) in combination with a standard anti-CD20 treatment (rituximab).
Product Name : PTG-007
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
September 09, 2024
Lead Product(s) : PTG-007,Rituximab
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : PTG-007,Rituximab
Therapeutic Area : Endocrinology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
PolTREG’s PTG-007 Shows Long-Term Safety in Type-1 Diabetes Treatment
Details : PTG-007, a treg cell therapy, in combination with rituximab, a CD20 inhibitor, is being investigated in a phase 1/2 trial for the treatment of type-1 diabetes.
Product Name : PTG-007
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
June 24, 2024
Lead Product(s) : PTG-007,Rituximab
Therapeutic Area : Endocrinology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : PTG-007,Rituximab
Therapeutic Area : Endocrinology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
PolTREG Identifies Efficacy Biomarker for Type-1 Diabetes Treated with Treg Therapy
Details : PTG-007, a treg cell therapy, in combination with rituximab, a CD20 inhibitor, is being investigated in a phase 1/2 trial for the treatment of type-1 diabetes.
Product Name : PTG-007
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
April 04, 2024
Lead Product(s) : PTG-007,Rituximab
Therapeutic Area : Endocrinology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable