Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : P-BCMA-ALLO1,Rimiducid
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : F. Hoffmann-La Roche
Deal Size : Not Applicable
Deal Type : Not Applicable
Poseida Reports Positive Interim Results For CAR-T Therapy in Myeloma
Details : P-BCMA-ALLO1 is a Phase 1 investigational novel BCMA-targeted allogeneic CAR-T product candidate, targeting B-cell maturation antigen (BCMA) for the treatment of relapsed/refractory multiple myeloma.
Brand Name : P-BCMA-ALLO1
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
September 27, 2024
Lead Product(s) : P-BCMA-ALLO1,Rimiducid
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : F. Hoffmann-La Roche
Deal Size : Not Applicable
Deal Type : Not Applicable
Poseida Wins RMAT Designation from FDA for Multiple Myeloma Therapy P-BCMA-ALLO1
Details : P-BCMA-ALLO1 is a RMAT designated novel BCMA-targeted allogeneic CAR-T product candidate, targeting B-cell maturation antigen for the treatment of relapsed/refractory multiple myeloma.
Brand Name : P-BCMA-ALLO1
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
September 16, 2024
Lead Product(s) : CAR-T Cell Therapy
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Sponsor : Xyphos Biosciences
Deal Size : $600.0 million
Deal Type : Collaboration
Astellas and Poseida Enter Research Collaboration for Cell Therapies
Details : Poseida and Xyphos will combine their technologies to develop a CAR-T construct targeting solid tumors, creating two convertibleCAR® product candidates.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : $50.0 million
May 01, 2024
Lead Product(s) : CAR-T Cell Therapy
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Sponsor : Xyphos Biosciences
Deal Size : $600.0 million
Deal Type : Collaboration
Lead Product(s) : P-BCMA-ALLO1,Rimiducid
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : F. Hoffmann-La Roche
Deal Size : Not Applicable
Deal Type : Not Applicable
Poseida Receives FDA Orphan Drug Designation for P-BCMA-ALLO1 in Multiple Myeloma
Details : P-BCMA-ALLO1 is a Phase 1 investigational novel BCMA-targeted allogeneic CAR-T product candidate, targeting B-cell maturation antigen (BCMA) for the treatment of relapsed/refractory multiple myeloma.
Brand Name : P-BCMA-ALLO1
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
March 13, 2024
Lead Product(s) : P-BCMA-ALLO1,Rimiducid
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : F. Hoffmann-La Roche
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : P-MUC1C-ALLO1,Rimiducid
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Astellas Pharma
Deal Size : $50.0 million
Deal Type : Licensing Agreement
Details : Under the agreement, Astellas gains a right of exclusive negotiation and first refusal to license one of Poseida's clinical stage programs, P-MUC1C-ALLO1, an allogeneic CAR-T cell therapy in development for multiple solid tumor indications.
Brand Name : P-MUC1C-ALLO1
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
August 07, 2023
Lead Product(s) : P-MUC1C-ALLO1,Rimiducid
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Astellas Pharma
Deal Size : $50.0 million
Deal Type : Licensing Agreement
Lead Product(s) : P-CD19CD20-ALLO1
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : F. Hoffmann-La Roche
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : P-CD19CD20-ALLO1 is a first allogeneic dual CAR-T cell therapy which targets both CD19 and CD20 antigens for the treatment of relapsed or refractory B-cell malignancies and is being developed in partnership with Roche.
Brand Name : P-CD19CD20-ALLO1
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
July 05, 2023
Lead Product(s) : P-CD19CD20-ALLO1
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : F. Hoffmann-La Roche
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : P-BCMA-ALLO1,Rimiducid
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : F. Hoffmann-La Roche
Deal Size : $6,220.0 million
Deal Type : Collaboration
Details : Under the agreement with Poseida, Roche to develop allogeneic CAR-T cell therapies for hematologic malignancies, including P-BCMA-ALLO1, an allogeneic CAR-T cell product to treat multiple myeloma, and P-CD19CD20-ALLO1 to treat B cell malignancies.
Brand Name : P-BCMA-ALLO1
Molecule Type : Cell and Gene therapy
Upfront Cash : $110.0 million
August 03, 2022
Lead Product(s) : P-BCMA-ALLO1,Rimiducid
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : F. Hoffmann-La Roche
Deal Size : $6,220.0 million
Deal Type : Collaboration
Details : The Phase 1 trial is an open label, multi-center, 3+3 dose-escalating study designed to assess the safety of P-PSMA-101 in up to 60 adult subjects with mCRPC. The primary objectives of this study are to determine the safety, efficacy, and maximum tolerat...
Brand Name : P-PSMA-101
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
February 17, 2022
Lead Product(s) : P-FVIII-101
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Takeda Pharmaceutical
Deal Size : $3,600.0 million
Deal Type : Collaboration
Details : Under the terms of the agreement, the collaboration to initially develop up to six in vivo gene therapy programs including P-FVIII-101, utilizing Poseida's novel technology platforms and biodegradable nanoparticle technology, as well as certain emerging ...
Brand Name : P-FVIII-101
Molecule Type : Cell and Gene therapy
Upfront Cash : $45.0 million
October 12, 2021
Lead Product(s) : P-FVIII-101
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Takeda Pharmaceutical
Deal Size : $3,600.0 million
Deal Type : Collaboration
Details : P-PSMA-101 is a High-Tscm Autologous CAR-T Targeting PSMA Producing Exceptionally Deep and Durable Responses in Castration-Resistant Metastatic Prostate Cancer.
Brand Name : P-PSMA-101
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
August 31, 2021
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