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Find Clinical Drug Pipeline Developments & Deals by Precigen

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : Precigen intends to use the net proceeds from the offering for advancing PRGN-2012 to regulatory approval for the treatment of Recurrent Respiratory Papillomatosis.

                          Brand Name : PRGN-2012

                          Molecule Type : Vaccine

                          Upfront Cash : Undisclosed

                          August 07, 2024

                          Lead Product(s) : PRGN-2012

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Stifel

                          Deal Size : $30.0 million

                          Deal Type : Public Offering

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                          02

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : PRGN-2012 a new molecular entity, a HPV 6/11-specific T-cell response inducer, is an off the shelf OTS AdenoVerse gene therapy vaccine. It is in Phase I/II for recurrent respiratory papillomatosis.

                          Brand Name : PRGN-2012

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          June 03, 2024

                          Lead Product(s) : PRGN-2012

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : National Cancer Institute

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : PRGN-2012, a therapeutic vaccine using gorilla adenovector technology, is in phase 1/2 clinical trials for treating recurrent respiratory papillomatosis.

                          Brand Name : PRGN-2012

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          January 16, 2024

                          Lead Product(s) : PRGN-2012

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : PRGN-2012 is an innovative therapeutic vaccine with optimized antigen design that uses Precigen’s gorilla adenovector technology (proprietary AdenoVerse platform), which is investigated for the treatment of recurrent respiratory papillomatosis.

                          Brand Name : PRGN-2012

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          August 09, 2023

                          Lead Product(s) : PRGN-2012

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : PRGN-2012 is an innovative therapeutic vaccine with optimized antigen design that uses Precigen’s gorilla adenovector technology (proprietary AdenoVerse platform), which is investigated for the treatment of recurrent respiratory papillomatosis.

                          Brand Name : PRGN-2012

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          June 20, 2023

                          Lead Product(s) : PRGN-2012

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : PRGN-2009 leverages Precigen’s UltraVector® and AdenoVerse™ platforms and is an off-the-shelf adenoVerse immunotherapy in combination with pembrolizumab being developed to treat patients with recurrent or metastatic cervical cancer.

                          Brand Name : PRGN-2009

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          May 31, 2023

                          Lead Product(s) : PRGN-2009,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : Under the agreement, Precigen regains exclusive rights to IL-12 gene therapy, including application through the AdenoVerse™ platform. Precigen will utilize the UltraCAR-T platform for unencumbered development and commercialization of two proven CAR-T t...

                          Brand Name : PRGN-3007

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          April 03, 2023

                          Lead Product(s) : Autologous CAR-T Cell-based Therapy,Fludarabine Phosphate,Cyclophosphamide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : Alaunos Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          08

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : PRGN-3007 is the next generation of UltraCAR-T incorporating PD-1 inhibition, it simultaneously express a chimeric antigen receptor (CAR) targeting ROR1, mbIL15, a kill switch, and a novel mechanism for the intrinsic blockade of PD-1 gene. expression.

                          Brand Name : PRGN-3007

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          March 29, 2023

                          Lead Product(s) : PRGN-3007,Cyclophosphamide,Fludarabine Phosphate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : PRGN-2012 is an innovative therapeutic vaccine with optimized antigen design that uses Precigen’s gorilla adenovector technology (proprietary AdenoVerse platform), to elicit immune responses directed against cells infected with human papillomavirus typ...

                          Brand Name : PRGN-2012

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          January 04, 2023

                          Lead Product(s) : PRGN-2012

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : PRGN-3006 UltraCAR-T is a multigenic autologous chimeric antigen receptor (CAR)-T simultaneously expressing a CAR specifically targeting CD33; membrane bound IL-15 (mbIL15) for enhanced in vivo expansion and persistence.

                          Brand Name : PRGN-3006

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          December 12, 2022

                          Lead Product(s) : PRGN-3006

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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