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Find Clinical Drug Pipeline Developments & Deals by Precision BioSciences
The Company intends to use the net proceeds to support its ongoing research and development, including PBGENE-HBV, designed to eliminate both cccDNA and inactivate HBV DNA. It is being evaluated for the treatment of Chronic Hepatitis B.
Precision exercised its option to regain rights for the programs, including its novel proprietary ARCUS® platform to develop in vivo gene editing therapies for sophisticated gene edits.
ECUR-506, incorporates an ARCUS nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and a donor vector that inserts the desired functional OTC gene for the treatment of Ornithine Transcarbamylase deficiency in infants.
The net proceeds will be used in the clinical development of PBGENE-HBV, designed to both eliminate cccDNA and inactivate HBV DNA. It is being evaluated for the treatment of Chronic Hepatitis B.
The net proceeds will be used in the clinical development of PBGENE-HBV, designed to both eliminate cccDNA and inactivate HBV DNA. It is being evaluated for the treatment of Chronic Hepatitis B.
PBGENE-HBV first and only potentially curative gene editing program that acts as a cccDNA/HBV DNA inhibitor. It is being developed for the treatment of chronic hepatitis B.
Under the agreement, TG Therapeutics received exclusive worldwide rights to develop and commercialize Precision’s Azercabtagene Zapreleucel (azer-cel), an allogeneic CD19 CAR T cell therapy program for autoimmune diseases and all other non-oncology indications.
Under the agreement, TG Therapeutics will receive exclusive worldwide rights to develop and commercialize Precision’s Azercabtagene Zapreleucel (azer-cel), an allogeneic CD19 CAR T cell therapy program for autoimmune diseases and all other non-oncology indications.
Arcus is a platform designed to develop in vivo gene editing therapies, including gene insertion, excision, and elimination. It has received TGA approval for initiation of Phase 1/2 trial evaluating ECUR-506 for the treatment of Ornithine Transcarbamylase (OTC) deficiency.
Imugene gains global rights to PBCAR0191 (azercabtagene zapreleucel), Precision’s lead allogeneic CAR T candidate, for cancer. Imugene will assume ongoing trial for azer-cel in the large B-cell lymphoma and has an option to develop up to three other cancer research programs.