Lead Product(s) : Prexasertib,Gemcitabine
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Acrivon Stops Testing Lilly Castoff for Ovarian, Bladder Cancer
Details : ACR-368 (prexasertib), a potent, selective CHK1/2 inhibitor, is deprioritized for ovarian and bladder cancers as targets and will be redirected to testing in endometrial cancer.
Product Name : ACR-368
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
March 26, 2025
Lead Product(s) : Prexasertib,Gemcitabine
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Prexasertib,Gemcitabine
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : RA Capital Management
Deal Size : $130.0 million
Deal Type : Private Placement
Acrivon Therapeutics Announces $130 Million Private Placement Financing
Details : The proceeds will advance ACR-368 (prexasertib), a selective small molecule inhibitor targeting CHK1 and CHK2 in Phase 2 trials, and its preclinical pipeline, including ACR-2316.
Product Name : ACR-368
Product Type : Cytotoxic Drug
Upfront Cash : Undisclosed
September 04, 2024
Lead Product(s) : Prexasertib,Gemcitabine
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : RA Capital Management
Deal Size : $130.0 million
Deal Type : Private Placement
Lead Product(s) : Prexasertib,Gemcitabine
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Jefferies
Deal Size : $99.4 million
Deal Type : Public Offering
Acrivon Therapeutics Announces Pricing of Initial Public Offering
Details : Acrivon is currently advancing its lead candidate, ACR-368 (prexasertib), a selective small molecule inhibitor targeting CHK1 and CHK2 in a potentially registrational Phase 2 trial across multiple tumor types.
Product Name : ACR-368
Product Type : Cytotoxic Drug
Upfront Cash : Undisclosed
November 15, 2022
Lead Product(s) : Prexasertib,Gemcitabine
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Jefferies
Deal Size : $99.4 million
Deal Type : Public Offering
Lead Product(s) : Prexasertib,Gemcitabine
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Wellington Management Company
Deal Size : $100.0 million
Deal Type : Series B Financing
Details : Proceeds will support the clinical development of advanced Phase 2 lead asset ACR-368, a potent DNA Damage Response (DDR) inhibitor clinically validated in solid cancers, and in-house drug pipeline driven by the company’s proprietary platform technolog...
Product Name : ACR-368
Product Type : Cytotoxic Drug
Upfront Cash : Undisclosed
November 11, 2021
Lead Product(s) : Prexasertib,Gemcitabine
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Wellington Management Company
Deal Size : $100.0 million
Deal Type : Series B Financing
Lead Product(s) : Prexasertib,Gemcitabine
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Acrivon intends to develop prexasertib (also called ACR-368) in accelerated clinical trials treating patients whose tumors are driven by, and depend on, dysregulated CHK1 and CHK2 using the OncoSignature® test.
Product Name : ACR-368
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
June 29, 2021
Lead Product(s) : Prexasertib,Gemcitabine
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable