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Find Clinical Drug Pipeline Developments & Deals for Prexasertib

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                          Top Deals by Deal Size (USD bn)

                          01

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : ACR-368 (prexasertib), a potent, selective CHK1/2 inhibitor, is deprioritized for ovarian and bladder cancers as targets and will be redirected to testing in endometrial cancer.

                          Product Name : ACR-368

                          Product Type : Cytotoxic Drug

                          Upfront Cash : Inapplicable

                          March 26, 2025

                          Lead Product(s) : Prexasertib,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : The proceeds will advance ACR-368 (prexasertib), a selective small molecule inhibitor targeting CHK1 and CHK2 in Phase 2 trials, and its preclinical pipeline, including ACR-2316.

                          Product Name : ACR-368

                          Product Type : Cytotoxic Drug

                          Upfront Cash : Undisclosed

                          September 04, 2024

                          Lead Product(s) : Prexasertib,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : RA Capital Management

                          Deal Size : $130.0 million

                          Deal Type : Private Placement

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                          03

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Acrivon is currently advancing its lead candidate, ACR-368 (prexasertib), a selective small molecule inhibitor targeting CHK1 and CHK2 in a potentially registrational Phase 2 trial across multiple tumor types.

                          Product Name : ACR-368

                          Product Type : Cytotoxic Drug

                          Upfront Cash : Undisclosed

                          November 15, 2022

                          Lead Product(s) : Prexasertib,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Jefferies

                          Deal Size : $99.4 million

                          Deal Type : Public Offering

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                          04

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Proceeds will support the clinical development of advanced Phase 2 lead asset ACR-368, a potent DNA Damage Response (DDR) inhibitor clinically validated in solid cancers, and in-house drug pipeline driven by the company’s proprietary platform technolog...

                          Product Name : ACR-368

                          Product Type : Cytotoxic Drug

                          Upfront Cash : Undisclosed

                          November 11, 2021

                          Lead Product(s) : Prexasertib,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Wellington Management Company

                          Deal Size : $100.0 million

                          Deal Type : Series B Financing

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                          05

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Acrivon intends to develop prexasertib (also called ACR-368) in accelerated clinical trials treating patients whose tumors are driven by, and depend on, dysregulated CHK1 and CHK2 using the OncoSignature® test.

                          Product Name : ACR-368

                          Product Type : Cytotoxic Drug

                          Upfront Cash : Inapplicable

                          June 29, 2021

                          Lead Product(s) : Prexasertib,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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