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Holdings","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Bio-Path Holdings \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Bio-Path Holdings \/ Inapplicable"},{"orgOrder":0,"company":"Bio-Path Holdings","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Oligonucleotide","year":"2020","type":"Inapplicable","leadProduct":"Prexigebersen","moa":"||GRB2","graph1":"Oncology","graph2":"Phase II","graph3":"Bio-Path Holdings","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Bio-Path Holdings \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Bio-Path Holdings \/ Inapplicable"},{"orgOrder":0,"company":"Bio-Path 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Holdings","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nutrition and Weight Loss","country":"U.S.A","productType":"Oligonucleotide","year":"2024","type":"Inapplicable","leadProduct":"Prexigebersen","moa":"GRB2","graph1":"Nutrition and Weight Loss","graph2":"Preclinical","graph3":"Bio-Path Holdings","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Nutrition & Weight Loss","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Bio-Path Holdings \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Bio-Path Holdings \/ Inapplicable"},{"orgOrder":0,"company":"Bio-Path Holdings","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Oligonucleotide","year":"2023","type":"Inapplicable","leadProduct":"Prexigebersen","moa":"GRB2","graph1":"Oncology","graph2":"Phase I","graph3":"Bio-Path Holdings","amount2":0,"highestDevelopmentShortName":"Ph 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Loss","country":"U.S.A","productType":"Oligonucleotide","year":"2025","type":"Inapplicable","leadProduct":"Prexigebersen","moa":"GRB2","graph1":"Nutrition and Weight Loss","graph2":"Preclinical","graph3":"Bio-Path Holdings","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Nutrition & Weight Loss","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Bio-Path Holdings \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Bio-Path Holdings \/ Inapplicable"}]

Find Clinical Drug Pipeline Developments & Deals for Prexigebersen

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                          01

                          ELCC
                          Not Confirmed
                          ELCC
                          Not Confirmed

                          Details : BP1001-A (prexigebersen) works by binding directly to Grb2 mRNA, preventing its translation into the Grb2 protein. It is currently being evaluated for the treatment of obesity.

                          Product Name : BP1001-A

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          March 18, 2025

                          Lead Product(s) : Prexigebersen

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          ELCC
                          Not Confirmed
                          ELCC
                          Not Confirmed

                          Details : BP1001-A works by binding directly to Grb2 mRNA, preventing its translation into the Grb2 protein. It is currently being evaluated for the treatment of obesity and related metabolic diseases.

                          Product Name : BP1001-A

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          December 19, 2024

                          Lead Product(s) : Prexigebersen

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          ELCC
                          Not Confirmed
                          ELCC
                          Not Confirmed

                          Details : BP1001-A works by binding directly to Grb2 mRNA, preventing its translation into the Grb2 protein. It is currently being evaluated for the treatment of obesity and related metabolic diseases.

                          Product Name : BP1001-A

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          December 11, 2024

                          Lead Product(s) : Prexigebersen

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          ELCC
                          Not Confirmed
                          ELCC
                          Not Confirmed

                          Details : BP1001-A works by binding directly to Grb2 mRNA, preventing its translation into the Grb2 protein. It is currently being evaluated for the treatment of obesity and related metabolic diseases.

                          Product Name : BP1001-A

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          October 08, 2024

                          Lead Product(s) : Prexigebersen

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          ELCC
                          Not Confirmed
                          ELCC
                          Not Confirmed

                          Details : BP1001-A, a modified product of prexigebersen, incorporates the same drug substance as prexigebersen but has a slightly altered formulation designed to enhance NP properties for solid tumors.

                          Product Name : BP1001-A

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          August 21, 2024

                          Lead Product(s) : Prexigebersen,Paclitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          ELCC
                          Not Confirmed
                          ELCC
                          Not Confirmed

                          Details : BP1001 (prexigebersen) is a neutral liposome incorporated with nuclease-resistant, hydrophobic P-ethoxy antisense oligodeoxynucleotides targeted to Grb2 mRNA, which is investigated for the treatment of acute myeloid leukemia.

                          Product Name : BP1001

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          August 01, 2023

                          Lead Product(s) : Prexigebersen,Decitabine,Ventoclax

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          ELCC
                          Not Confirmed
                          ELCC
                          Not Confirmed

                          Details : BP1001-A is a modified drug product with the same drug substance as Bio-Path’s lead drug candidate, prexigebersen, but includes formulation enhancements to produce smaller drug nanoparticles, being investigated for Solid Tumors.

                          Product Name : BP1001-A

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          July 17, 2023

                          Lead Product(s) : Prexigebersen

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          ELCC
                          Not Confirmed
                          ELCC
                          Not Confirmed

                          Details : BP1001-A is a modified drug product with the same drug substance as prexigebersen but includes formulation enhancements to produce smaller drug nanoparticles.

                          Product Name : BP1001-A

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          December 07, 2022

                          Lead Product(s) : Prexigebersen,Paclitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          ELCC
                          Not Confirmed
                          ELCC
                          Not Confirmed

                          Details : United States Patent and Trademark Office has granted U.S. Patent titled, "P-ethoxy nucleic acids for liposomal formulation." The new patent builds on earlier patents granted that protect the platform technology for DNAbilize®, the Company’s novel RN...

                          Product Name : BP1001

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          February 10, 2021

                          Lead Product(s) : Prexigebersen,Decitabine,Ventoclax

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          ELCC
                          Not Confirmed
                          ELCC
                          Not Confirmed

                          Details : The U.S Patent and Trademark Office has issued a notice of allowance for claims related to the Company’s lead product candidate, prexigebersen, in combination with either a cytidine analogue, like decitabine, or the Bcr-Abl tyrosine kinase inhibitors d...

                          Product Name : BP1001

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          October 22, 2020

                          Lead Product(s) : Prexigebersen,Decitabine,Venetoclax

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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