Lead Product(s) : Prexigebersen
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Bio-Path Holdings Initiates Development of Therapeutic Program for Treatment of Obesity
Details : BP1001-A works by binding directly to Grb2 mRNA, preventing its translation into the Grb2 protein. It is currently being evaluated for the treatment of obesity and related metabolic diseases.
Brand Name : BP1001-A
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 08, 2024
Lead Product(s) : Prexigebersen
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Prexigebersen,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Bio-Path Reports Solid Tumor Patient Response to BP1001-A Treatment
Details : BP1001-A, a modified product of prexigebersen, incorporates the same drug substance as prexigebersen but has a slightly altered formulation designed to enhance NP properties for solid tumors.
Brand Name : BP1001-A
Molecule Type : Large molecule
Upfront Cash : Not Applicable
August 21, 2024
Lead Product(s) : Prexigebersen,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Prexigebersen,Decitabine,Ventoclax
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BP1001 (prexigebersen) is a neutral liposome incorporated with nuclease-resistant, hydrophobic P-ethoxy antisense oligodeoxynucleotides targeted to Grb2 mRNA, which is investigated for the treatment of acute myeloid leukemia.
Brand Name : BP1001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
August 01, 2023
Lead Product(s) : Prexigebersen,Decitabine,Ventoclax
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Prexigebersen
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BP1001-A is a modified drug product with the same drug substance as Bio-Path’s lead drug candidate, prexigebersen, but includes formulation enhancements to produce smaller drug nanoparticles, being investigated for Solid Tumors.
Brand Name : BP1001-A
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 17, 2023
Lead Product(s) : Prexigebersen
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Prexigebersen,Decitabine
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Bio-Path Receives Third U.S. Patent Grant Related to Manufacture of Platform Technology
Details : United States Patent and Trademark Office has granted U.S. Patent titled, "P-ethoxy nucleic acids for liposomal formulation." The new patent builds on earlier patents granted that protect the platform technology for DNAbilize®, the Company’s novel RN...
Brand Name : BP1001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
February 10, 2021
Lead Product(s) : Prexigebersen,Decitabine
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Prexigebersen,Decitabine,Venetoclax
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The U.S Patent and Trademark Office has issued a notice of allowance for claims related to the Company’s lead product candidate, prexigebersen, in combination with either a cytidine analogue, like decitabine, or the Bcr-Abl tyrosine kinase inhibitors d...
Brand Name : BP1001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 22, 2020
Lead Product(s) : Prexigebersen,Decitabine,Venetoclax
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Prexigebersen,Decitabine,Venetoclax
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : First patient in the amended Stage 2 of the Phase 2 clinical study of prexigebersen (BP1001), for the treatment of acute myeloid leukemia (AML), in combination with frontline therapy decitabine and venetoclax, has been enrolled.
Brand Name : BP1001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
August 13, 2020
Lead Product(s) : Prexigebersen,Decitabine,Venetoclax
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Prexigebersen,Decitabine
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Bio-Path Holdings Presents at 2020 American Society of Clinical Oncology Annual Meeting
Details : The poster describes the Phase 2 study design of BP1001 (liposomal Grb2 antisense), the Company’s lead drug candidate, in combination with decitabine as a potential treatment for patients diagnosed with acute myeloid leukemia (AML) or high-risk myelody...
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 29, 2020
Lead Product(s) : Prexigebersen,Decitabine
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Prexigebersen
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Bio-Path Holdings Provides Clinical Update and 2020 Business Outlook
Details : Bio-Path Holdings is planning to conduct a Phase 2 Study of Prexigebersen in Untreated and Refractory/Resistant Acute Myeloid Leukemia (AML) and High-Risk Myelodysplastic Syndrome (MDS) Patients.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 08, 2020
Lead Product(s) : Prexigebersen
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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