Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Semaglutide
Therapeutic Area : Endocrinology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ProLynx Unveils Monthly Dosing Preclinical Results for Long-Acting Semaglutide
Details : Semaglutide is a peptide GLP-1 agonist, peptide drug candidate, which is being evaluated for the treatment of type 2 diabetes & obesity.
Brand Name : Undisclosed
Molecule Type : Peptide
Upfront Cash : Not Applicable
August 21, 2024
Lead Product(s) : Semaglutide
Therapeutic Area : Endocrinology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ProLynx Initiates Phase II of PLX038 in Triple-Negative Breast Cancer at Institut Curie
Details : PLX038 is a long-acting prodrug of the topoisomerase 1 (Top1) inhibitor, SN-38. It is being evaluated for the treatment of locally-advanced or metastatic triple-negative breast cancer.
Brand Name : PLX038
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 25, 2024
Lead Product(s) : PLX038
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ProLynx Initiates Phase I/II of PLX038 in Rare CNS Tumors at National Cancer Institute
Details : PLX038 is a long-acting prodrug of the topoisomerase 1 inhibitor, It is being evaluated in phase 1/2 clinical trials for the treatment of primary CNS tumors driven by MYC or MYCN amplifications.
Brand Name : PLX038
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 05, 2024
Lead Product(s) : PLX038
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : 7-Ethyl-10-Hydroxycamptothecin
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : National Cancer Institute
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PLX038 (PEG~SN-38) is a long-acting PEGylated prodrug of SN-38, the active metabolite of the approved anti-cancer agents irinotecan and Trodelvy® (sacituzumab govitecan). SN-38 is a potent inhibitor of topoisomerase 1 (topo1) that causes inhibition of D...
Brand Name : PLX038
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 07, 2022
Lead Product(s) : 7-Ethyl-10-Hydroxycamptothecin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : National Cancer Institute
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Teriparatide
Therapeutic Area : Endocrinology
Study Phase : Preclinical
Sponsor : National Institutes of Health
Deal Size : Undisclosed
Deal Type : Funding
ProLynx announces SBIR Arant Award to Develop Long-Ating Parathyroid Hormone for Hypo-Parathyroidism
Details : The grant was conferred for the development of a long acting parathyroid hormone – PTH(1-34) – that can be administered once-weekly for treatment of hypo-parathyroidism.
Brand Name : PTH(1-34)
Molecule Type : Peptide
Upfront Cash : Undisclosed
July 07, 2020
Lead Product(s) : Teriparatide
Therapeutic Area : Endocrinology
Highest Development Status : Preclinical
Sponsor : National Institutes of Health
Deal Size : Undisclosed
Deal Type : Funding
Lead Product(s) : 7-Ethyl-10-Hydroxycamptothecin,Rucaparib Camsylate
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ProLynx announces Phase 1B clinical trial of its DNA-damaging agent PLX038 (PEG~SN-38)
Details : PLX038 (PEG~SN-38) is a long-acting PEGylated prodrug of SN-38, the active metabolite of the approved anti-cancer agents irinotecan and Trodelvy® (sacituzumab govitecan). SN-38 is a potent inhibitor of topoisomerase 1 (topo1) that causes inhibition of D...
Brand Name : PLX038
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 13, 2020
Lead Product(s) : 7-Ethyl-10-Hydroxycamptothecin,Rucaparib Camsylate
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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