Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Imifoplatin
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Promontory Completes Enrollment of PT112 in Castration-Resistant Prostate Cancer
Details : PT-112 (imifoplatin) is the first small-molecule conjugate of pyrophosphate in clinical development in oncology. It is being evaluated for metastatic castration-resistant prostate cancer.
Brand Name : PT-112
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 08, 2024
Lead Product(s) : Imifoplatin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Imifoplatin
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PT-112 (imifoplatin) is the first small-molecule conjugate of pyrophosphate in clinical development in oncology and inhibitor of ribosomal biogenesis (RiBi) that bind to dendritic cells and lead to downstream immune effector cell recruitment in the tumor...
Brand Name : PT-112
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 05, 2023
Lead Product(s) : Imifoplatin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Imifoplatin
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PT-112 is the first small-molecule conjugate of pyrophosphate in clinical development in oncology and inhibitor of ribosomal biogenesis (RiBi) that bind to dendritic cells and lead to downstream immune effector cell recruitment in the tumor microenvironm...
Brand Name : PT-112
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 20, 2023
Lead Product(s) : Imifoplatin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Imifoplatin
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PT-112 is the first small-molecule conjugate of pyrophosphate that promotes immunogenic cell death, through the release of damage associated molecular patterns that bind to dendritic cells and lead to downstream immune effector cell recruitment in the tu...
Brand Name : PT-112
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 02, 2023
Lead Product(s) : Imifoplatin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Imifoplatin,Avelumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PT-112 is the first small-molecule conjugate of pyrophosphate in oncology, and possesses a unique pleiotropic mechanism of action that promotes immunogenic cell death (ICD), through the release of damage associated molecular patterns (DAMPs).
Brand Name : PT-112
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 08, 2022
Lead Product(s) : Imifoplatin,Avelumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Imifoplatin
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PT-112 is the first small-molecule conjugate of pyrophosphate, and possesses a unique pleiotropic MOA that promotes ICD, through the release of DAMPs that bind to dendritic cells and lead to downstream immune effector cell recruitment in the tumor microe...
Brand Name : PT-112
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 12, 2022
Lead Product(s) : Imifoplatin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Imifoplatin
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PT-112 is the first small-molecule conjugate of pyrophosphate in oncology, and possesses a unique pleiotropic mechanism of action that promotes immunogenic cell death (ICD) through the release of damage associated molecular patterns (DAMPs) that bind to ...
Brand Name : PT-112
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 08, 2022
Lead Product(s) : Imifoplatin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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