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I","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Inhalation","sponsorNew":"Qnovia \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Qnovia \/ Inapplicable"},{"orgOrder":0,"company":"Miist Therapeutics","sponsor":"Refactor Capital","pharmaFlowCategory":"D","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Undisclosed","year":"2025","type":"Financing","leadProduct":"MST-01","moa":"nAChR","graph1":"Psychiatry\/Psychology","graph2":"Phase I","graph3":"Miist Therapeutics","amount2":0.01,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Psychiatry","amount2New":0.01,"dosageForm":"Inhalation","sponsorNew":"Miist Therapeutics \/ Refactor Capital","highestDevelopmentStatusID":"6","companyTruncated":"Miist Therapeutics \/ Refactor Capital"}]

Find Psychiatry/Psychology Drugs in Phase I Clinical Development

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          RNA Therapeutics
                          Not Confirmed
                          RNA Therapeutics
                          Not Confirmed

                          Details : The financing aims to advance the Miist clinical product MST-01, which is being evaluated for the treatment of smoking addiction.

                          Product Name : MST-01

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          February 05, 2025

                          Lead Product(s) : MST-01

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I

                          Sponsor : Refactor Capital

                          Deal Size : $7.0 million

                          Deal Type : Financing

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                          02

                          RNA Therapeutics
                          Not Confirmed
                          RNA Therapeutics
                          Not Confirmed

                          Details : The financing aims to advance the clinical development of SJP-001. It is designed to help not only treat the signs and symptoms of Veisalgia (alcohol hangover).

                          Product Name : SJP-001

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          January 22, 2025

                          Lead Product(s) : Naproxen,Fexofenadine Hydrochloride

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I

                          Sponsor : 5 Horizons Capital

                          Deal Size : Undisclosed

                          Deal Type : Financing

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                          03

                          RNA Therapeutics
                          Not Confirmed
                          RNA Therapeutics
                          Not Confirmed

                          Details : The financing aims to advance the clinical development of RespiRx Nicotine Inhaler (QN-01), a prescription inhaled smoking cessation medicine.

                          Product Name : Undisclosed

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          December 10, 2024

                          Lead Product(s) : QN-01

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I

                          Sponsor : Blue Ledge Capital

                          Deal Size : $16.0 million

                          Deal Type : Series B Financing

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                          04

                          RNA Therapeutics
                          Not Confirmed
                          RNA Therapeutics
                          Not Confirmed

                          Details : DLX-001 is the first of several psychoplastogens which promotes rapid and enduring neuroplasticity, without hallucinatory responses even at high doses. It is being investigated for MDD.

                          Product Name : Undisclosed

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 04, 2024

                          Lead Product(s) : DLX-001

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          RNA Therapeutics
                          Not Confirmed
                          RNA Therapeutics
                          Not Confirmed

                          Details : ML-007/PAC is an extended-release, fixed-dose combination of M1/M4 agonist, co-formulated with PAC. It is being investigated for schizophrenia and Alzheimer's disease psychosis.

                          Product Name : Undisclosed

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 02, 2024

                          Lead Product(s) : ML-007,Undisclosed

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          RNA Therapeutics
                          Not Confirmed
                          RNA Therapeutics
                          Not Confirmed

                          Details : AL001 (lithium salicylate proline) is an oral small molecule BDNF inhibitor. It is being developed for the treatment of petients with major depressive disorder.

                          Product Name : AL001

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 19, 2024

                          Lead Product(s) : Lithium Salicylate Proline

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          RNA Therapeutics
                          Not Confirmed
                          RNA Therapeutics
                          Not Confirmed

                          Details : EVX-101 is a novel, proprietary gastro-retentive, sustained-release tablet formulation of 5-HTP, the natural precursor to serotonin. It is under trials for the treatment of major depressive disorder.

                          Product Name : EVX-101

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 25, 2024

                          Lead Product(s) : HSDB 4295,Carbidopa

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          RNA Therapeutics
                          Not Confirmed
                          RNA Therapeutics
                          Not Confirmed

                          Details : ABX-002 is a highly potent, oral, thyroid hormone beta receptor (TRβ) selective agonist, which is being evaluated for the treatment of bipolar depression.

                          Product Name : ABX-002

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 22, 2024

                          Lead Product(s) : ABX-002

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          RNA Therapeutics
                          Not Confirmed
                          RNA Therapeutics
                          Not Confirmed

                          Details : SP-624 is a novel SIRT6 activator, small molecule drug candidate, which is being evaluated for the treatment of major depressive disorder.

                          Product Name : SP-624

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 10, 2024

                          Lead Product(s) : SP-624

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          RNA Therapeutics
                          Not Confirmed
                          RNA Therapeutics
                          Not Confirmed

                          Details : ENX-104 is a selective dopamine D2/D3R antagonist designed to enhance dopamine neurotransmission by preferential autoreceptor inhibition. It is being evaluated for Major Depressive Disorders.

                          Product Name : ENX-104

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 18, 2024

                          Lead Product(s) : ENX-104

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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