15
ALL5
Aptinyx1
Neurocentria1
Nobilis Therapeutics1
Otsuka Pharmaceutical5
Praxis Precision Medicines1
Sunovion Pharmaceuticals1
The University of British ColumbiaYear
15
ALL1
20241
20235
20223
20215
2020DEALS // DEV.
15
ALL3
Deals12
DevelopmentsCountry
15
ALL1
CANADA1
JAPAN13
U.S.A15
ALL1
BofA Securities1
Cowen1
Eventide Asset Management10
Inapplicable1
Otsuka America Pharmaceutical, Inc.1
Sunovion PharmaceuticalsTherapeutic Area
15
ALL15
Psychiatry/PsychologyStudy Phase
15
ALL15
Phase II/ Phase IIIDeal Type
15
ALL12
Inapplicable2
Public Offering1
Series C FinancingProduct Type
15
ALL1
Controlled Substance13
Other Small Molecule1
Vitamins/Minerals/Inorganic SaltsDosage Form
15
ALL5
Oral Capsule1
Oral Inhalation5
Oral Suspension2
Oral Tablet2
UndisclosedLead Product
15
ALL1
Cannabidiol1
Magnesium L-Threonate5
NYX-7835
PRAX-1142
Ulotaront1
XenonTarget
15
ALL1
CB1/2 receptor5
GABAA receptor6
NMDA receptor2
TAA1 receptor1
UndisclosedLead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : Alvogen
Deal Size : $345.0 million
Deal Type : Collaboration
NRx Pharmaceuticals Announces $5 Million Milestone from Alvogen and Lotus Pharma
Details : The collaborations aim to support NRx for the development of NRX-101 (D-cycloserine) in the treatment of bipolar depression with suicidality.
Product Name : NRX-101
Product Type : Other Small Molecule
Upfront Cash : $10.0 million
November 02, 2024
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : Alvogen
Deal Size : $345.0 million
Deal Type : Collaboration
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
NRx Reports Trial Results Showing Safety of NRX-101 in Suicidal Bipolar Depression
Details : NRX-101 (D-cycloserine & Lurasidone HCl) is a fixed dose combination which is under clinical development for various indications including for the treatment of suicidal bipolar depression.
Product Name : NRX-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 05, 2024
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
NRx Announces Promising Findings in Phase 2b/3 of NRX-101 for Suicidal Bipolar Depression
Details : NRX-101 (D-cycloserine & Lurasidone HCl) is a fixed dose combination which is under clinical development for various indications including for the treatment of suicidal bipolar depression.
Product Name : NRX-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 30, 2024
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
NRx Pharmaceuticals Announces Last Patient, Last Visit in Phase 2b/3 Trial Of NRX-101
Details : NRX-101, a combination of the NMDA antagonist D-cycloserine and lurasidone, is in phase 2/3 trials for treating resistant bipolar depression and suicidal ideation.
Product Name : NRX-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 03, 2024
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Cannabidiol
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
UBC Researchers Launch Clinical Trial Exploring CBD for Bipolar Depression
Details : ProZ-001 (cannabidiol) is a CB1 receptor negative allosteric modulator, which is approved for the treatment of patients with dravet syndrome and lennox-gastaut syndrome.
Product Name : ProZ-001
Product Type : Controlled Substance
Upfront Cash : Inapplicable
February 27, 2024
Lead Product(s) : Cannabidiol
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
NRx Pharmaceuticals Completes Enrollment Of Phase 2b/3 Trial Of NRX-101
Details : NRX-101, a fixed-dose combination of D-cycloserine and lurasidone, is in phase 2/3 trials for treatment-resistant bipolar depression and suicidal ideation.
Product Name : NRX-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 22, 2024
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : Lotus Pharmaceutical Industries
Deal Size : $345.0 million
Deal Type : Collaboration
Details : The collaboration aims to develop and commercialize NRX-101, an fixed dose oral combination of D-cycloserine and lurasidone for treatment-resistant suicidal bipolar depression (S-TRBD). It is one of the first oral antidepressants targeting the NMDA recep...
Product Name : NRX-101
Product Type : Other Small Molecule
Upfront Cash : $10.0 million
July 06, 2023
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : Lotus Pharmaceutical Industries
Deal Size : $345.0 million
Deal Type : Collaboration
Lead Product(s) : Ulotaront
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : Otsuka America Pharmaceutical, Inc.
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : SEP-363856 (ulotaront) is a TAAR1 agonist with 5-HT1A agonist activity, is currently under investigation for the treatment of schizophrenia, generalized anxiety disorder and the adjunctive treatment of MDD with additional indications under consideration.
Product Name : SEP-363856
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 26, 2023
Lead Product(s) : Ulotaront
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : Otsuka America Pharmaceutical, Inc.
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tobacco Leaf Extract
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : Bpifrance
Deal Size : $1.8 million
Deal Type : Funding
NFL Biosciences Receives € 1.7 Million In « Avance Innovation » Funding From Bpifrance
Details : The funding will be used to complete the CESTO II clinical study designed to evaluate the efficacy and safety of its NFL-101 (tobacco leaf protein) treatment as a smoking cessation therapy.
Product Name : NFL-101
Product Type : Plant Extract/Herbal
Upfront Cash : Undisclosed
February 20, 2023
Lead Product(s) : Tobacco Leaf Extract
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : Bpifrance
Deal Size : $1.8 million
Deal Type : Funding
Lead Product(s) : Tobacco Leaf Extract
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : CEA
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the terms of the collaboration, NFL-Biosciences will use the CEA's molecular imaging resources to better understand the mechanism of action of NFL 101. NFL-101, is a standardized, nicotine free tobacco leaf extract protected by two patent families.
Product Name : NFL-101
Product Type : Plant Extract/Herbal
Upfront Cash : Undisclosed
February 02, 2023
Lead Product(s) : Tobacco Leaf Extract
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : CEA
Deal Size : Undisclosed
Deal Type : Collaboration