Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
NRx Reports Trial Results Showing Safety of NRX-101 in Suicidal Bipolar Depression
Details : NRX-101 (D-cycloserine & Lurasidone HCl) is a fixed dose combination which is under clinical development for various indications including for the treatment of suicidal bipolar depression.
Brand Name : NRX-101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 06, 2024
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
NRx Announces Promising Findings in Phase 2b/3 of NRX-101 for Suicidal Bipolar Depression
Details : NRX-101 (D-cycloserine & Lurasidone HCl) is a fixed dose combination which is under clinical development for various indications including for the treatment of suicidal bipolar depression.
Brand Name : NRX-101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 30, 2024
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
NRx Pharmaceuticals Announces Last Patient, Last Visit in Phase 2b/3 Trial Of NRX-101
Details : NRX-101, a combination of the NMDA antagonist D-cycloserine and lurasidone, is in phase 2/3 trials for treating resistant bipolar depression and suicidal ideation.
Brand Name : NRX-101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 04, 2024
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Cannabidiol
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
UBC Researchers Launch Clinical Trial Exploring CBD for Bipolar Depression
Details : ProZ-001 (cannabidiol) is a CB1 receptor negative allosteric modulator, which is approved for the treatment of patients with dravet syndrome and lennox-gastaut syndrome.
Brand Name : ProZ-001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 27, 2024
Lead Product(s) : Cannabidiol
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : Alvogen
Deal Size : $345.0 million
Deal Type : Collaboration
NRx Pharmaceuticals Announces $5 Million Milestone from Alvogen and Lotus Pharma
Details : The collaborations aim to support NRx for the development of NRX-101 (D-cycloserine) in the treatment of bipolar depression with suicidality.
Brand Name : NRX-101
Molecule Type : Small molecule
Upfront Cash : $10.0 million
February 11, 2024
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : Alvogen
Deal Size : $345.0 million
Deal Type : Collaboration
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
NRx Pharmaceuticals Completes Enrollment Of Phase 2b/3 Trial Of NRX-101
Details : NRX-101, a fixed-dose combination of D-cycloserine and lurasidone, is in phase 2/3 trials for treatment-resistant bipolar depression and suicidal ideation.
Brand Name : NRX-101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 22, 2024
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : Lotus Pharmaceuticals
Deal Size : $345.0 million
Deal Type : Collaboration
Details : The collaboration aims to develop and commercialize NRX-101, an fixed dose oral combination of D-cycloserine and lurasidone for treatment-resistant suicidal bipolar depression (S-TRBD). It is one of the first oral antidepressants targeting the NMDA recep...
Brand Name : NRX-101
Molecule Type : Small molecule
Upfront Cash : $10.0 million
June 07, 2023
Lead Product(s) : Cycloserine,Lurasidone Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : Lotus Pharmaceuticals
Deal Size : $345.0 million
Deal Type : Collaboration
Lead Product(s) : Ulotaront
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : Otsuka America Pharmaceutical, Inc.
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : SEP-363856 (ulotaront) is a TAAR1 agonist with 5-HT1A agonist activity, is currently under investigation for the treatment of schizophrenia, generalized anxiety disorder and the adjunctive treatment of MDD with additional indications under consideration.
Brand Name : SEP-363856
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 26, 2023
Lead Product(s) : Ulotaront
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : Otsuka America Pharmaceutical, Inc.
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NFL-101
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : Bpifrance
Deal Size : $1.8 million
Deal Type : Funding
NFL Biosciences Receives € 1.7 Million In « Avance Innovation » Funding From Bpifrance
Details : The funding will be used to complete the CESTO II clinical study designed to evaluate the efficacy and safety of its NFL-101 (tobacco leaf protein) treatment as a smoking cessation therapy.
Brand Name : NFL-101
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 20, 2023
Lead Product(s) : NFL-101
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : Bpifrance
Deal Size : $1.8 million
Deal Type : Funding
Lead Product(s) : NFL-101
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II/ Phase III
Sponsor : CEA
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the terms of the collaboration, NFL-Biosciences will use the CEA's molecular imaging resources to better understand the mechanism of action of NFL 101. NFL-101, is a standardized, nicotine free tobacco leaf extract protected by two patent families.
Brand Name : NFL-101
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 02, 2023
Lead Product(s) : NFL-101
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II/ Phase III
Sponsor : CEA
Deal Size : Undisclosed
Deal Type : Collaboration
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