Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Dihydroergotamine Mesylate
Therapeutic Area : Neurology
Study Phase : Phase I
Recipient : Mannkind
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Pulmatrix Announces Cross License Agreement and Transfer of Laboratory to MannKind
Details : MannKind will grant Pulmatrix a royalty free, exclusive license to use MannKind's Cricket inhalation device for the inhaled delivery of PUR3100, a proprietary formulation of dihydroergotamine.
Brand Name : PUR3100
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 30, 2024
Lead Product(s) : Dihydroergotamine Mesylate
Therapeutic Area : Neurology
Highest Development Status : Phase I
Recipient : Mannkind
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Itraconazole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Cipla
Deal Size : Undisclosed
Deal Type : Agreement
Pulmatrix Stops PUR1900 Phase 2B Enrollment To Preserve Cash
Details : Under the amendment, Cipla and Pulmatrix agreed to halt patient enrollment in the Ph2b study of PUR1900 (itraconazole) at 8 subjects, with Cipla assuming sole responsibility for its development.
Brand Name : PUR1900
Molecule Type : Small molecule
Upfront Cash : $22.0 million
January 08, 2024
Lead Product(s) : Itraconazole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Cipla
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Dihydroergotamine Mesylate
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Pulmatrix Announces FDA Acceptance of IND Application for PUR3100 to Treat Acute Migraine
Details : PUR3100 is an orally inhaled formulation of dihydroergotamine (DHE) engineered with iSPERSE™ technology, which is investigated for the treatment of acute migraine.
Brand Name : PUR3100
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 19, 2023
Lead Product(s) : Dihydroergotamine Mesylate
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Dihydroergotamine Mesylate
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PUR3100 dry powder inhaler is under development as an orally inhaled dihydroergotamine (DHE) engineered with iSPERSE™ for the acute treatment of migraine.
Brand Name : PUR3100
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 11, 2023
Lead Product(s) : Dihydroergotamine Mesylate
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Dihydroergotamine Mesylate
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PUR3100 (dihydroergotamine) is under development as an orally inhaled DHE engineered with iSPERSE™ for the acute treatment of migraine. The PUR3100 formulation is designed to disperse to the deep lung and rapidly enter the systemic circulation.
Brand Name : PUR3100
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 25, 2023
Lead Product(s) : Dihydroergotamine Mesylate
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : PUR1800
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PUR1800 is a narrow spectrum Kinase Inhibitor, engineered with our iSPERSE™ technology, being developed for the treatment of acute exacerbations in chronic obstructive pulmonary disease (AECOPD). PUR1800 targets p38 MAP kinases (p38MAPK), Src kinases, ...
Brand Name : PUR1800
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 23, 2023
Lead Product(s) : PUR1800
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Dihydroergotamine Mesylate
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PUR3100 (Dihydroergotamine) is under development as an orally inhaled DHE engineered with iSPERSE™ for the acute treatment of migraine. The PUR3100 formulation is designed to disperse to the deep lung and rapidly enter the systemic circulation.
Brand Name : PUR3100
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 04, 2023
Lead Product(s) : Dihydroergotamine Mesylate
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Dihydroergotamine Mesylate
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Pulmatrix Announces First Subject Dosed in Phase 1 Study of PUR3100 for Acute Migraine
Details : PUR3100, a novel pulmonary inhaled formulation of dihydroergotamine (DHE). PUR3100 is formulated using Pulmatrix's iSPERSE drug delivery technology and is being developed for the treatment of acute migraine.
Brand Name : PUR3100
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 12, 2022
Lead Product(s) : Dihydroergotamine Mesylate
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : PUR1800
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Medicines Evaluation Unit
Deal Size : Not Applicable
Deal Type : Not Applicable
Pulmatrix Announces Positive Top-Line Data Evaluating PUR1800 in Patients with Stable COPD
Details : PUR1800, a narrow-spectrum kinase inhibitor was well-tolerated and there were no observed safety signals. The preliminary PK data indicate that PUR1800 results in low and consistent systemic exposure when administered via oral inhalation.
Brand Name : PUR1800
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 21, 2022
Lead Product(s) : PUR1800
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Medicines Evaluation Unit
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Itraconazole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : H.C. Wainwright & Co
Deal Size : $40.0 million
Deal Type : Public Offering
Pulmatrix Announces Closing of $40 Million Registered Direct Offering
Details : Pulmatrix's product pipeline is initially focused on advancing treatments for serious lung diseases, including Pulmazole, an inhaled anti-fungal for patients with allergic bronchopulmonary aspergillosis, and PUR1800, a narrow spectrum kinase inhibitor in...
Brand Name : Pulmazole
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 16, 2021
Lead Product(s) : Itraconazole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : H.C. Wainwright & Co
Deal Size : $40.0 million
Deal Type : Public Offering
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