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01

Lead Product(s) : Dupilumab

Therapeutic Area : Pulmonary/Respiratory Diseases

Study Phase : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Dupixent (dupilumab), a fully human monoclonal antibody that inhibits the signaling of the IL-4 and IL-13 pathways, reduced COPD exacerbations in Phase 3 trial.

Product Name : Dupixent

Product Type : Antibody

Upfront Cash : Inapplicable

November 27, 2023

Lead Product(s) : Dupilumab

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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02

Lead Product(s) : Aviptadil Acetate

Therapeutic Area : Pulmonary/Respiratory Diseases

Study Phase : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Aviptadil is a synthetic form of vasoactive intestinal peptide (VIP) that, when administered, results in rapid clinical recovery in patients with severe SARS-COV-2 infection. Biophore has successfully developed aviptadil and is backward integrated with i...

Product Name : Undisclosed

Product Type : Peptide

Upfront Cash : Inapplicable

November 06, 2021

Lead Product(s) : Aviptadil Acetate

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Biophore

03

Lead Product(s) : Dupilumab

Therapeutic Area : Pulmonary/Respiratory Diseases

Study Phase : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Phase 3 trial showed Dupixent® (dupilumab) significantly reduced severe asthma attacks, and within two weeks rapidly improved lung function in children aged 6 to 11 years with uncontrolled moderate-to-severe asthma, with evidence of type 2 inflammation.

Product Name : Dupixent

Product Type : Antibody

Upfront Cash : Inapplicable

May 17, 2021

Lead Product(s) : Dupilumab

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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04

German Wound Congress
Not Confirmed
German Wound Congress
Not Confirmed

Details : The financing aims to advance the clinical development of ADL-018 (omalizumab), which is being evaluated for the treatment of asthma.

Product Name : ADL-018

Product Type : Antibody

Upfront Cash : Undisclosed

April 07, 2025

Lead Product(s) : Omalizumab

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase III

Sponsor : GoldenTree

Deal Size : Undisclosed

Deal Type : Financing

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05

German Wound Congress
Not Confirmed
German Wound Congress
Not Confirmed

Details : ADL-018 (omalizumab) is an antibody inhibiting IgE binding. It is being evaluated to treat chronic spontaneous urticaria & moderate to severe persistent asthma.

Product Name : ADL-018

Product Type : Antibody

Upfront Cash : Inapplicable

March 26, 2025

Lead Product(s) : Omalizumab

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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06

German Wound Congress
Not Confirmed
German Wound Congress
Not Confirmed

Details : Nucala (mepolizumab) is the first targeted anti-Interleukin-5 (IL-5) biologic. It is being investigated for the treament of COPD with an eosinophilic phenotype.

Product Name : Nucala

Product Type : Antibody

Upfront Cash : Inapplicable

March 24, 2025

Lead Product(s) : Mepolizumab

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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07

German Wound Congress
Not Confirmed
German Wound Congress
Not Confirmed

Details : ATYR1923 (efzofitimod) is a tRNA synthetase-derived therapy based on a naturally occurring, lung-enriched, splice variant of HARS. It is being evaluated for pulmonary sarcoidosis.

Product Name : ATYR1923

Product Type : Protein

Upfront Cash : Inapplicable

March 06, 2025

Lead Product(s) : Efzofitimod

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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08

German Wound Congress
Not Confirmed
German Wound Congress
Not Confirmed

Details : INS1007 (brensocatib), a DPP1 inhibitor, could be the first approved treatment for non-cystic fibrosis bronchiectasis. The company has announced +ve top-line results from its Phase 3 ASPEN study.

Product Name : INS1007

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

February 24, 2025

Lead Product(s) : Brensocatib

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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09

German Wound Congress
Not Confirmed
German Wound Congress
Not Confirmed

Details : MesenCure is an allogeneic cell therapy investigational drug comprising enhanced adipose tissue-derived MSC designed to treat inflammation and tissue damage in ARDS patients.

Product Name : MesenCure

Product Type : Cell and Gene therapy

Upfront Cash : Inapplicable

February 20, 2025

Lead Product(s) : Allogeneic Cell Therapy

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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10

German Wound Congress
Not Confirmed
German Wound Congress
Not Confirmed

Details : BI 1015550 (nerandomilast) is an investigational oral, preferential inhibitor of phosphodiesterase 4B (PDE4B) that is being studied as a potential treatment for progressive pulmonary fibrosis.

Product Name : BI 1015550

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

February 10, 2025

Lead Product(s) : Nerandomilast

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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