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PXS‐5505 has progressed to a phase 2 clinical trial looking for evidence of disease modifying effects in the bone cancer myelofibrosis as a monotherapy so exploring its additional potential to address cancers where fibrosis is limiting the clinical benefit of chemotherapy.
Lead Product(s): PXS-5505,Atezolizumab,Bevacizumab
Therapeutic Area: Oncology Product Name: PXS-5505
Highest Development Status: Phase II Product Type: Small molecule
Partner/Sponsor/Collaborator: University of Rochester
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable November 09, 2021
Details:
PXS‐5505 is currently progressing well through a phase 1c/2 clinical trial looking for evidence of disease modifying effects in bone cancer myelofibrosis as a monotherapy.
Lead Product(s): PXS-5505
Therapeutic Area: Oncology Product Name: PXS-5505
Highest Development Status: IND Enabling Product Type: Small molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable August 05, 2021
Details:
The phase 1c/2a trial MF‐101 aims to demonstrate that PXS‐5505 is safe and effective as a monotherapy in myelofibrosis patients who are intolerant, unresponsive or ineligible for treatment with approved JAK inhibitor drugs.
Lead Product(s): PXS-5505
Therapeutic Area: Oncology Product Name: PXS-5505
Highest Development Status: Phase II Product Type: Small molecule
Partner/Sponsor/Collaborator: Parexel Biotech
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable August 04, 2021