Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : MAN-01
Therapeutic Area : Ophthalmology
Study Phase : Preclinical
Sponsor : Mannin Research
Deal Size : $42.3 million
Deal Type : Agreement
Details : By utilizing MRI’s internal pro-forma revenue projections for 2023 & 2024 and comparable market transactions, MRI’s drug development pipeline including MAN-01 and companion diagnostics, are estimated to achieve a net present value.
Brand Name : MAN-01
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 14, 2022
Lead Product(s) : MAN-01
Therapeutic Area : Ophthalmology
Highest Development Status : Preclinical
Sponsor : Mannin Research
Deal Size : $42.3 million
Deal Type : Agreement
Lead Product(s) : Uttroside B
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Oklahoma Medical Research Foundation
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Present study attests to previous report that Uttroside-B is pharmacologically safe up to five times IC50 dose in acute and sub-chronic toxicity models, while even IC50 dose of sorafenib is toxic to immunocompromised mice, and elevated doses of sorafenib...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 26, 2022
Lead Product(s) : Uttroside B
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Oklahoma Medical Research Foundation
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Uttroside B
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : In the initial Scientific Reports study, researchers showed that in animal models, Uttroside-B was ten times more cytotoxic to the HepG2 liver cancer cell line than sorafenib, the only drug approved by the FDA for liver cancer approved at the time.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 16, 2022
Lead Product(s) : Uttroside B
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Strontium-89 Chloride
Therapeutic Area : Musculoskeletal
Study Phase : Approved
Sponsor : Chengdu Syncor Pharmaceutical
Deal Size : Undisclosed
Deal Type : Agreement
Q BioMed Announces Initial $500k Order of Strontium89 to Chinese Market
Details : The agreement is expected to be a high-growth opportunity to supply Strontium89 in the Chinese market. Strontium89 is FDA-approved, non-opioid radiopharmaceutical indicated for the treatment of painful skeletal metastases caused by cancer and is agnostic...
Brand Name : Metastron
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 07, 2022
Lead Product(s) : Strontium-89 Chloride
Therapeutic Area : Musculoskeletal
Highest Development Status : Approved
Sponsor : Chengdu Syncor Pharmaceutical
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : MAN-19
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Mannin Research
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MAN-19 therapeutic is a recombinant fusion protein that treats the patient, instead of targeting the virus. It is not a cure for COVID, but it strengthens a patient's blood vessels and protects them against ARDS, breathing problems, sepsis and other infe...
Brand Name : MAN-19
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 22, 2021
Lead Product(s) : MAN-19
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Mannin Research
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Strontium Chloride, Sr-89
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : isoSolutions
Deal Size : Undisclosed
Deal Type : Agreement
Q BioMed Signs Distribution Agreement with isoSolutions for the Sales of Strontium89 in Canada
Details : Strontium89 is an FDA-approved, non-opioid radiopharmaceutical indicated for the treatment of painful skeletal metastases caused by cancer and is agnostic of the primary tumor.
Brand Name : Metastron
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 10, 2021
Lead Product(s) : Strontium Chloride, Sr-89
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : isoSolutions
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Strontium Chloride, Sr-89
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Clionix
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Under the terms of the agreement, Clionix has received exclusive rights to distribute Strontium89 in Turkey, Saudi Arabia, Azerbaijan, Bulgaria, Romania, Egypt, Kuwait & Pakistan.
Brand Name : Metastron
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 12, 2021
Lead Product(s) : Strontium Chloride, Sr-89
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Clionix
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Uttroside B
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Q BioMed's Uttroside-B Receives Additional Patent Coverage in Canada and Japan
Details : The patent titled “Uttroside-B and Derivatives Thereof as Therapeutics for Hepatocellular Carcinoma” is a Method Of Use patent that covers the use of Uttroside-B for the treatment of hepatocellular carcinoma (HCC).
Brand Name : Uttroside-B
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 26, 2021
Lead Product(s) : Uttroside B
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : MAN-19
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Human and genetic studies, as well as animal models of endothelial dysfunction collectively suggest that by targeting Tie2 receptor, MAN-19 may be effective in the treatment of a number of complications associated with viral infections such as COVID-19 a...
Brand Name : MAN-19
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 26, 2020
Lead Product(s) : MAN-19
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : COVID-19 drug
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Discovery
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Q BioMed Initiates Rapid Development of Novel COVID-19 Therapeutics
Details : The Joint venture will deploy Cyclica's unique AI platform to accelerate the development of new treatments based on Mannin's Tie2 based platform.
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Not Applicable
April 22, 2020
Lead Product(s) : COVID-19 drug
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Discovery
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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