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The study will evaluate the safety, optimal dose and tumour response of the tigilanol tiglate and pembrolizumab combination in patients with late-stage unresectable melanoma, who have been previously exposed to immune checkpoint inhibitors.
Lead Product(s): Tigilanol Tiglate,Pembrolizumab
Therapeutic Area: Oncology Product Name: EBC-46
Highest Development Status: Phase I/ Phase II Product Type: Small molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable June 02, 2021
Details:
The Phase I/II open label 'QBC46-H06' study is a dose escalation and expansion study with the primary objective of determining the maximum tolerated dose or maximum feasible dose of tigilanol tiglate, in combination with Keytruda® (pembrolizumab) therapy.
Lead Product(s): Tigilanol Tiglate,Pembrolizumab
Therapeutic Area: Oncology Product Name: EBC-46
Highest Development Status: Phase I/ Phase II Product Type: Small molecule
Recipient: Merck & Co
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Collaboration August 13, 2020