Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Infigratinib
Therapeutic Area : Oncology
Study Phase : Phase II
Recipient : LianBio
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Truseltiq (infigratinib) is an oral small molecule, ATP-competitive, FGFR1-3 tyrosine kinase inhibitor in development for the treatment of FGFR-driven gastric cancer or gastroesophageal junction adenocarcinoma and to target achondroplasia at its source.
Brand Name : BGJ398
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 06, 2023
Lead Product(s) : Infigratinib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Recipient : LianBio
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Infigratinib
Therapeutic Area : Oncology
Study Phase : Phase II
Recipient : BridgeBio Pharma
Deal Size : $2,000.0 million
Deal Type : Collaboration
Details : BridgeBio will retain all rights to infigratinib in skeletal dysplasia, including achondroplasia. Subject to U.S. FDA approval, QED and Helsinn will co-commercialize infigratinib in oncology indications in the U.S. and will share profits and losses on a ...
Brand Name : BGJ398
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 31, 2021
Lead Product(s) : Infigratinib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Recipient : BridgeBio Pharma
Deal Size : $2,000.0 million
Deal Type : Collaboration
Lead Product(s) : Infigratinib
Therapeutic Area : Oncology
Study Phase : Phase III
Recipient : BridgeBio Pharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The U.S. FDA has accepted New Drug Application (NDA) for infigratinib, an oral FGFR1-3 selective inhibitor, for individuals with cholangiocarcinoma, or cancer of the bile ducts. Application accepted under Priority Review designation.
Brand Name : BGJ398
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 01, 2020
Lead Product(s) : Infigratinib
Therapeutic Area : Oncology
Highest Development Status : Phase III
Recipient : BridgeBio Pharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Infigratinib
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Data will be presented reports consistent treatment response in both first-line and later-line treatment settings after Infigratinib (BGJ398) treatment in advanced/unresectable or metastatic urothelial carcinoma.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 29, 2020
Lead Product(s) : Infigratinib
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Infigratinib
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
QED Therapeutics begins patient dosing in ph3 and ph 2 trials of Infigratinib
Details : The PROOF 302 trial is studying infigratinib for adjuvant treatment of invasive urothelial carcinoma. Second, investigator-initiated trial, is studying infigratinib for the treatment of solid tumors.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 12, 2020
Lead Product(s) : Infigratinib
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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