Lead Product(s) : Quemliclustat,Zimberelimab,Etrumadenant
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Taiho Pharmaceutical
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Taiho Exercises License Option for Quemliclustat in Japan and Asia
Details : Under the license agreement, Taiho will further support the development & commercialization of AB680 (quemliclustat) & will operationalize the PRISM-1 study in Japan as part of its mission.
Brand Name : AB680
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 08, 2024
Lead Product(s) : Quemliclustat,Zimberelimab,Etrumadenant
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Taiho Pharmaceutical
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Quemliclustat,Zimberelimab,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Quemliclustat-Based Regimens Show Survival Promise in Metastatic Pancreatic Cancer
Details : AB680 (quemliclustat) is an investigational CD73 inhibitor undergoing phase 1 trials in combination with zimberelimab and chemotherapy for metastatic pancreatic cancer.
Brand Name : AB680
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 16, 2024
Lead Product(s) : Quemliclustat,Zimberelimab,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Quemliclustat,Zimberelimab,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Gilead Sciences
Deal Size : Not Applicable
Deal Type : Not Applicable
Quemliclustat-Based Regimens Show Promising Survival in Metastatic Pancreatic Cancer
Details : AB680 (quemliclustat) is an investigational small molecule CD73 inhibitor in phase 1 development, evaluated in combination with chemotherapy for treatment-naïve metastatic pancreatic cancer.
Brand Name : AB680
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 16, 2024
Lead Product(s) : Quemliclustat,Zimberelimab,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Gilead Sciences
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Quemliclustat,Zimberelimab,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Preliminary data from the first dose-escalation cohorts, reported in an abstract released today, demonstrate encouraging signs of clinical activity for AB680 in combination with zimberelimab (anti-PD-1 antibody) and chemotherapy.
Brand Name : AB680
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 11, 2021
Lead Product(s) : Quemliclustat,Zimberelimab,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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