Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Sponsor : Variational AI
Deal Size : Undisclosed
Deal Type : Collaboration
Rakovina Therapeutics and Variational AI Announce Drug Discovery Collaboration
Details : The collaboration aimed at leveraging each company’s expertise to identify and develop novel small-molecule therapies against DNA-damage response targets for the treatment of cancer.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
September 17, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Sponsor : Variational AI
Deal Size : Undisclosed
Deal Type : Collaboration
Rakovina Therapeutics Closes Previously Announced Over-subscribed Private Placement
Details : The net proceeds will be used to fund the advancement of research and development of Rakoniva AI drug-discovery product KT-2000 for the treatment of neoplasms.
Brand Name : KT-2000
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 26, 2024
Rakovina Announces Oversubscribed Private Placement and 2024 Annual Meeting Results
Details : The net proceeds will be used to fund the advancement of research and development of Rakoniva AI drug-discovery product KT-2000 for the treatment of neoplasms.
Brand Name : KT-2000
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 20, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Sponsor : Pharma Inventor
Deal Size : Undisclosed
Deal Type : Collaboration
Rakovina Therapeutics Expands Strategic Collaborations to Support AI Research
Details : The collaboration aims to synthesize novel lead drug candidates identified by the Deep Docking AI platform for further validation, with Rakovina Therapeutics owning rights to developed molecules.
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Undisclosed
May 08, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Sponsor : Pharma Inventor
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : kt-3000
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Undisclosed
Deal Type : Financing
Rakovina Therapeutics Inc. Announces Closing of $1.5 Million Convertible Debenture Financing
Details : Rakovina will advance its lead kt-3000 program toward human clinical trials. kt-3000 class drug candidates are rationally designed to overcome treatment resistance by selectively downregulating DNA double-strand repair mechanisms while enhancing PARP inh...
Brand Name : kt-3000
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 29, 2023
Lead Product(s) : kt-3000
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Undisclosed
Deal Type : Financing
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : NRC IRAP
Deal Size : $0.1 million
Deal Type : Funding
Rakovina Therapeutics Receives Funding to Accelerate Development of Novel Cancer Therapies
Details : The funding will support the development of assays and animal models for evaluation of the Company’s novel classes of DNA-damage response inhibitors with selection of one or more lead compounds for advancement to toxicology, including kt-3000 series du...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 22, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : NRC IRAP
Deal Size : $0.1 million
Deal Type : Funding
Lead Product(s) : KT-3000
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Rakovina Therapeutics Announces Presentation at the 6th Annual DDR-inhibitors Summit
Details : Development of Rakovina Therapeutics’ novel kt-3000 bi-functional DNA-damage response inhibitors is supported, by the St. Baldrick’s Foundation Martha’s BEST Grant for All, which is aimed at developing new treatments for Ewing sarcoma.
Brand Name : KT-3000
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 26, 2023
Lead Product(s) : KT-3000
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : kt-3283
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : kt-3283 is a novel dual-function single molecule of PARP and HDAC in Ewing sarcoma model systems. In an Ewing sarcoma metastasis model, kt-3283 prevented metastatic cancer growth in the lungs of mice inoculated with an aggressive Ewing sarcoma cell line.
Brand Name : kt-3283
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 14, 2022
Lead Product(s) : kt-3283
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Kt-3000
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : kt-3000 class drug candidates are rationally designed to overcome treatment resistance by selectively downregulating DNA double-strand (DSB) repair mechanisms while enhancing PARP inhibitor activity.
Brand Name : Kt-3000
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 31, 2022
Lead Product(s) : Kt-3000
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Kt-3000
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The newly presented in vitro data suggest promising activity for our novel kt-3000 series drug candidates as a potential treatment for Ewing sarcoma and other treatment-resistant cancers.
Brand Name : Kt-3000
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 11, 2022
Lead Product(s) : Kt-3000
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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