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Find Clinical Drug Pipeline Developments & Deals by Rakovina Therapeutics

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The collaboration aimed at leveraging each company’s expertise to identify and develop novel small-molecule therapies against DNA-damage response targets for the treatment of cancer.

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          September 17, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery Platform

                          Sponsor : Variational AI

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The net proceeds will be used to fund the advancement of research and development of Rakoniva AI drug-discovery product KT-2000 for the treatment of neoplasms.

                          Brand Name : KT-2000

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          July 26, 2024

                          Lead Product(s) : KT-2000

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery

                          Sponsor : Undisclosed

                          Deal Size : Undisclosed

                          Deal Type : Private Placement

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The net proceeds will be used to fund the advancement of research and development of Rakoniva AI drug-discovery product KT-2000 for the treatment of neoplasms.

                          Brand Name : KT-2000

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          June 20, 2024

                          Lead Product(s) : KT-2000

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery

                          Sponsor : Undisclosed

                          Deal Size : $2.0 million

                          Deal Type : Private Placement

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                          04

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The collaboration aims to synthesize novel lead drug candidates identified by the Deep Docking AI platform for further validation, with Rakovina Therapeutics owning rights to developed molecules.

                          Brand Name : Undisclosed

                          Molecule Type : Undisclosed

                          Upfront Cash : Undisclosed

                          May 08, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery Platform

                          Sponsor : Pharma Inventor

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          05

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Rakovina will advance its lead kt-3000 program toward human clinical trials. kt-3000 class drug candidates are rationally designed to overcome treatment resistance by selectively downregulating DNA double-strand repair mechanisms while enhancing PARP inh...

                          Brand Name : kt-3000

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          May 29, 2023

                          Lead Product(s) : kt-3000

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Undisclosed

                          Deal Size : Undisclosed

                          Deal Type : Financing

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                          06

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The funding will support the development of assays and animal models for evaluation of the Company’s novel classes of DNA-damage response inhibitors with selection of one or more lead compounds for advancement to toxicology, including kt-3000 series du...

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          March 22, 2023

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : NRC IRAP

                          Deal Size : $0.1 million

                          Deal Type : Funding

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                          07

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Development of Rakovina Therapeutics’ novel kt-3000 bi-functional DNA-damage response inhibitors is supported, by the St. Baldrick’s Foundation Martha’s BEST Grant for All, which is aimed at developing new treatments for Ewing sarcoma.

                          Brand Name : KT-3000

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          January 26, 2023

                          Lead Product(s) : KT-3000

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : kt-3283 is a novel dual-function single molecule of PARP and HDAC in Ewing sarcoma model systems. In an Ewing sarcoma metastasis model, kt-3283 prevented metastatic cancer growth in the lungs of mice inoculated with an aggressive Ewing sarcoma cell line.

                          Brand Name : kt-3283

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 14, 2022

                          Lead Product(s) : kt-3283

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : kt-3000 class drug candidates are rationally designed to overcome treatment resistance by selectively downregulating DNA double-strand (DSB) repair mechanisms while enhancing PARP inhibitor activity.

                          Brand Name : Kt-3000

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 31, 2022

                          Lead Product(s) : Kt-3000

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The newly presented in vitro data suggest promising activity for our novel kt-3000 series drug candidates as a potential treatment for Ewing sarcoma and other treatment-resistant cancers.

                          Brand Name : Kt-3000

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          May 11, 2022

                          Lead Product(s) : Kt-3000

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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