Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : RLYB212
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Rallybio Announces Initiation of Phase 2 Clinical Trial of RLYB212
Details : RLYB212, an anti-HPA-1a monoclonal antibody and once monthly subcutaneous administration, being developed for the prevention of fetal and neonatal alloimmune thrombocytopenia.
Brand Name : RLYB212
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 21, 2024
Lead Product(s) : RLYB212
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : RLYB212
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Johnson & Johnson Innovative Medicine
Deal Size : $6.6 million
Deal Type : Collaboration
Rallybio Collaborates on Solutions for Fetal Alloimmune Thrombocytopenia
Details : Under this collaboration, Johnson & Johnson will fund Rallybio's RLYB212, the sole investigational therapy aimed at addressing the needs of pregnant individuals at risk of FNAIT.
Brand Name : RLYB212
Molecule Type : Large molecule
Upfront Cash : Undisclosed
April 10, 2024
Lead Product(s) : RLYB212
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Johnson & Johnson Innovative Medicine
Deal Size : $6.6 million
Deal Type : Collaboration
Lead Product(s) : RLYB116
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : RLYB116 is a novel antibody mimetic fusion protein, long-acting C5 inhibitor. It is being evaluated in phase 1 clinical trials for patients with complement-mediated diseases.
Brand Name : RLYB116
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 20, 2023
Lead Product(s) : RLYB116
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : RLYB212
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : RLYB212, an anti-HPA-1a monoclonal antibody and once monthly subcutaneous administration, being developed for the prevention of fetal and neonatal alloimmune thrombocytopenia.
Brand Name : RLYB212
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 28, 2023
Lead Product(s) : RLYB212
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : RLYB212
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : RLYB212 to rapidly accelerate the elimination of HPA-1a positive platelets transfused to HPA-1a negative healthy male participants. It is being developed to prevent fetal and neonatal alloimmune thrombocytopenia.
Brand Name : RLYB212
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 24, 2023
Lead Product(s) : RLYB212
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : RLYB211
Therapeutic Area : Immunology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : RLYB211 is a polyclonal anti-HPA-1a antibody derived from human plasma, it is being investigated for the prevention of fetal and neonatal alloimmune thrombocytopenia (FNAIT).
Brand Name : RLYB211
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 06, 2023
Lead Product(s) : RLYB211
Therapeutic Area : Immunology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : RLYB212
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : RLYB212 to rapidly accelerate the elimination of HPA-1a positive platelets transfused to HPA-1a negative healthy male participants. It is being developed to prevent fetal and neonatal alloimmune thrombocytopenia.
Brand Name : RLYB212
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 06, 2023
Lead Product(s) : RLYB212
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : RLYB114
Therapeutic Area : Ophthalmology
Study Phase : Preclinical
Recipient : EyePoint Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The partnership will evaluate sustained delivery of Rallybio’s inhibitor of complement component 5 using EyePoint’s proprietary Durasert technology for sustained intraocular drug delivery. RLYB114 is a C5-targeted Affibody® molecule conjugated to po...
Brand Name : RLYB114
Molecule Type : Peptide
Upfront Cash : Undisclosed
February 27, 2023
Lead Product(s) : RLYB114
Therapeutic Area : Ophthalmology
Highest Development Status : Preclinical
Recipient : EyePoint Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : RLYB212
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The results demonstrate that low doses of the two HPA-1a-specific antibodies, the polyclonal candidate RLYB211 and the monoclonal candidate RLYB212, are equally effective at rapidly clearing HPA-1a-positive platelets from circulation and preventing alloi...
Brand Name : RLYB212
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 15, 2022
Lead Product(s) : RLYB212
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Antibody-based Therapy
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Discovery Platform
Recipient : AbCellera
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the terms of the agreement, AbCellera and Rallybio will co-develop up to five rare disease novel antibody-based therapeutic targets, which will be chosen together by both companies.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
December 01, 2022
Lead Product(s) : Antibody-based Therapy
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Discovery Platform
Recipient : AbCellera
Deal Size : Undisclosed
Deal Type : Collaboration
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