16
ALL12
ALX Oncology1
Basilea Pharmaceutica2
Eli Lilly1
Innovent BiologicsYear
16
ALL1
20251
20245
20234
20222
20213
2020DEALS // DEV.
16
ALL6
Deals10
DevelopmentsCountry
16
ALL1
CHINA1
SWITZERLAND14
U.S.A16
ALL1
ALX Oncology3
Eli Lilly8
Inapplicable1
Innovent Biologics3
Piper SandlerTherapeutic Area
16
ALL16
OncologyStudy Phase
16
ALL2
Approved FDF11
Phase II/ Phase III1
Phase II1
Phase I/ Phase II1
Phase IDeal Type
16
ALL2
Collaboration10
Inapplicable1
Partnership3
Public OfferingProduct Type
16
ALL3
Antibody13
ProteinDosage Form
16
ALL16
Intravenous InfusionLead Product
16
ALL13
Evorpacept3
RamucirumabTarget
16
ALL13
CD473
VEGFR2Lead Product(s) : Evorpacept,Ramucirumab
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
ALX Presents Updated Data from ASPEN-06 Phase 2 Trial in HER2-Positive Gastric Cancer
Details : ALX148 (evorpacept) is a next generation CD47 blocker, which is being investigated in combination with trastuzumab in patients with HER2-positive gastric/gastroesophageal junction (“GEJ”) cancer.
Product Name : ALX148
Product Type : Protein
Upfront Cash : Inapplicable
January 23, 2025
Lead Product(s) : Evorpacept,Ramucirumab
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Evorpacept,Ramucirumab
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
ALX Reports Phase 2 Data Showing Evorpacept Improves HER2-Positive Gastric Cancer Response
Details : ALX148 (evorpacept) is a next generation CD47 blocker, which is being investigated in combination with trastuzumab in patients with HER2-positive gastric/gastroesophageal junction (“GEJ”) cancer.
Product Name : ALX148
Product Type : Protein
Upfront Cash : Inapplicable
July 31, 2024
Lead Product(s) : Evorpacept,Ramucirumab
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Evorpacept,Ramucirumab
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Piper Sandler
Deal Size : $63.2 million
Deal Type : Public Offering
Details : ALX Oncology will use the proceeds to fund ongoing development of ALX148 (evorpacept), a next generation CD47 blocking therapeutic that combines a high-affinity CD47 binding domain with an inactivated, proprietary Fc domain, for hematologic and solid mal...
Product Name : ALX148
Product Type : Protein
Upfront Cash : Undisclosed
October 10, 2023
Lead Product(s) : Evorpacept,Ramucirumab
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Piper Sandler
Deal Size : $63.2 million
Deal Type : Public Offering
Lead Product(s) : Evorpacept,Ramucirumab
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Eli Lilly
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ALX148 (evorpacept) is a next generation CD47 blocker, which is being investigated in patients with gastric cancer and gastroesophageal junction adenocarcinoma.
Product Name : ALX148
Product Type : Protein
Upfront Cash : Inapplicable
June 26, 2023
Lead Product(s) : Evorpacept,Ramucirumab
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Eli Lilly
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Evorpacept,Ramucirumab
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Piper Sandler
Deal Size : $55.0 million
Deal Type : Public Offering
ALX Oncology Announces Pricing of Public Offering
Details : ALX Oncology will use the proceeds to fund ongoing development of ALX148 (evorpacept), a next generation CD47 blocking therapeutic that combines a high-affinity CD47 binding domain with an inactivated, proprietary Fc domain, for hematologic and solid mal...
Product Name : ALX148
Product Type : Protein
Upfront Cash : Undisclosed
May 10, 2023
Lead Product(s) : Evorpacept,Ramucirumab
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Piper Sandler
Deal Size : $55.0 million
Deal Type : Public Offering
Lead Product(s) : Evorpacept,Ramucirumab
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Piper Sandler
Deal Size : Undisclosed
Deal Type : Public Offering
ALX Oncology Announces Proposed Public Offering
Details : ALX Oncology will use the proceeds to fund ongoing development of ALX148 (evorpacept), a next generation CD47 blocking therapeutic that combines a high-affinity CD47 binding domain with an inactivated, proprietary Fc domain, for hematologic and solid mal...
Product Name : ALX148
Product Type : Protein
Upfront Cash : Undisclosed
April 10, 2023
Lead Product(s) : Evorpacept,Ramucirumab
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Piper Sandler
Deal Size : Undisclosed
Deal Type : Public Offering
Lead Product(s) : Evorpacept,Ramucirumab
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ALX148 (evorpacept) is a next generation CD47 blocker, which is being investigated in combination with trastuzumab in patients with HER2-positive gastric/gastroesophageal junction (“GEJ”) cancer.
Product Name : ALX148
Product Type : Protein
Upfront Cash : Inapplicable
March 10, 2023
Lead Product(s) : Evorpacept,Ramucirumab
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ramucirumab
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Eli Lilly
Deal Size : Inapplicable
Deal Type : Inapplicable
Details :
Product Name : Cyramza
Product Type : Antibody
Upfront Cash : Inapplicable
October 10, 2022
Lead Product(s) : Ramucirumab
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Eli Lilly
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ramucirumab
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Innovent Biologics
Deal Size : $45.0 million
Deal Type : Partnership
Innovent and Lilly Expand Strategic Partnership in Oncology
Details : Under the terms of the agreement, upon regulatory approvals of Cyramza® in the hepatocellular carcinoma indication and Retsevmo® in the non-small lung cancer indication, and then intends to commercialize Cyramza® and Retsevmo® in China.
Product Name : Cyramza
Product Type : Antibody
Upfront Cash : Undisclosed
March 28, 2022
Lead Product(s) : Ramucirumab
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Innovent Biologics
Deal Size : $45.0 million
Deal Type : Partnership
Lead Product(s) : Evorpacept,Ramucirumab
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Evorpacept used in combination with ramucirumab, trastuzumab, and paclitaxel demonstrated an initial confirmed objective response rate of 72.2% with a median duration of response of 14.8 months, a 12-month overall survival rate of 79%.
Product Name : ALX148
Product Type : Protein
Upfront Cash : Inapplicable
February 03, 2022
Lead Product(s) : Evorpacept,Ramucirumab
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable