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Offering","leadProduct":"Evorpacept","moa":"||CD47","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"ALX Oncology","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"ALX Oncology \/ Piper Sandler","highestDevelopmentStatusID":"9","companyTruncated":"ALX Oncology \/ Piper Sandler"},{"orgOrder":0,"company":"ALX Oncology","sponsor":"Piper Sandler","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2023","type":"Public Offering","leadProduct":"Evorpacept","moa":"||CD47","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"ALX Oncology","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"ALX Oncology \/ Piper Sandler","highestDevelopmentStatusID":"9","companyTruncated":"ALX Oncology \/ Piper Sandler"},{"orgOrder":0,"company":"ALX Oncology","sponsor":"Piper Sandler","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2023","type":"Public Offering","leadProduct":"Evorpacept","moa":"||CD47","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"ALX Oncology","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"ALX Oncology \/ Piper Sandler","highestDevelopmentStatusID":"9","companyTruncated":"ALX Oncology \/ Piper Sandler"},{"orgOrder":0,"company":"Eli Lilly","sponsor":"Innovent Biologics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2022","type":"Partnership","leadProduct":"Ramucirumab","moa":"VEGFR2","graph1":"Oncology","graph2":"Approved FDF","graph3":"Eli Lilly","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Eli Lilly \/ Innovent Biologics","highestDevelopmentStatusID":"15","companyTruncated":"Eli Lilly \/ Innovent Biologics"},{"orgOrder":0,"company":"ALX Oncology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2023","type":"Inapplicable","leadProduct":"Evorpacept","moa":"||CD47","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"ALX Oncology","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"ALX Oncology \/ Inapplicable","highestDevelopmentStatusID":"9","companyTruncated":"ALX Oncology \/ Inapplicable"},{"orgOrder":0,"company":"ALX Oncology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2024","type":"Inapplicable","leadProduct":"Evorpacept","moa":"||CD47","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"ALX Oncology","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"ALX Oncology \/ Inapplicable","highestDevelopmentStatusID":"9","companyTruncated":"ALX Oncology \/ Inapplicable"},{"orgOrder":0,"company":"ALX Oncology","sponsor":"Eli Lilly","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2023","type":"Inapplicable","leadProduct":"Evorpacept","moa":"||CD47","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"ALX Oncology","amount2":0,"highestDevelopmentShortName":"Ph 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II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"ALX Oncology \/ Inapplicable","highestDevelopmentStatusID":"9","companyTruncated":"ALX Oncology \/ Inapplicable"},{"orgOrder":0,"company":"ALX Oncology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2020","type":"Inapplicable","leadProduct":"Evorpacept","moa":"||CD47","graph1":"Oncology","graph2":"Phase II","graph3":"ALX Oncology","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"ALX Oncology \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"ALX Oncology \/ Inapplicable"},{"orgOrder":0,"company":"ALX 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II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"ALX Oncology \/ Inapplicable","highestDevelopmentStatusID":"9","companyTruncated":"ALX Oncology \/ Inapplicable"}]

Find Clinical Drug Pipeline Developments & Deals for Ramucirumab

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01

Interphex
Not Confirmed
Interphex
Not Confirmed

Details : ALX148 (evorpacept) is a next generation CD47 blocker, which is being investigated in combination with trastuzumab in patients with HER2-positive gastric/gastroesophageal junction (“GEJ”) cancer.

Product Name : ALX148

Product Type : Protein

Upfront Cash : Inapplicable

January 23, 2025

Lead Product(s) : Evorpacept,Ramucirumab

Therapeutic Area : Oncology

Highest Development Status : Phase II/ Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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02

Interphex
Not Confirmed
Interphex
Not Confirmed

Details : ALX148 (evorpacept) is a next generation CD47 blocker, which is being investigated in combination with trastuzumab in patients with HER2-positive gastric/gastroesophageal junction (“GEJ”) cancer.

Product Name : ALX148

Product Type : Protein

Upfront Cash : Inapplicable

July 31, 2024

Lead Product(s) : Evorpacept,Ramucirumab

Therapeutic Area : Oncology

Highest Development Status : Phase II/ Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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03

Interphex
Not Confirmed
Interphex
Not Confirmed

Details : ALX Oncology will use the proceeds to fund ongoing development of ALX148 (evorpacept), a next generation CD47 blocking therapeutic that combines a high-affinity CD47 binding domain with an inactivated, proprietary Fc domain, for hematologic and solid mal...

Product Name : ALX148

Product Type : Protein

Upfront Cash : Undisclosed

October 10, 2023

Lead Product(s) : Evorpacept,Ramucirumab

Therapeutic Area : Oncology

Highest Development Status : Phase II/ Phase III

Sponsor : Piper Sandler

Deal Size : $63.2 million

Deal Type : Public Offering

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04

Interphex
Not Confirmed
Interphex
Not Confirmed

Details : ALX148 (evorpacept) is a next generation CD47 blocker, which is being investigated in patients with gastric cancer and gastroesophageal junction adenocarcinoma.

Product Name : ALX148

Product Type : Protein

Upfront Cash : Inapplicable

June 26, 2023

Lead Product(s) : Evorpacept,Ramucirumab

Therapeutic Area : Oncology

Highest Development Status : Phase II/ Phase III

Sponsor : Eli Lilly

Deal Size : Inapplicable

Deal Type : Inapplicable

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05

Interphex
Not Confirmed
Interphex
Not Confirmed

Details : ALX Oncology will use the proceeds to fund ongoing development of ALX148 (evorpacept), a next generation CD47 blocking therapeutic that combines a high-affinity CD47 binding domain with an inactivated, proprietary Fc domain, for hematologic and solid mal...

Product Name : ALX148

Product Type : Protein

Upfront Cash : Undisclosed

May 10, 2023

Lead Product(s) : Evorpacept,Ramucirumab

Therapeutic Area : Oncology

Highest Development Status : Phase II/ Phase III

Sponsor : Piper Sandler

Deal Size : $55.0 million

Deal Type : Public Offering

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06

Interphex
Not Confirmed
Interphex
Not Confirmed

Details : ALX Oncology will use the proceeds to fund ongoing development of ALX148 (evorpacept), a next generation CD47 blocking therapeutic that combines a high-affinity CD47 binding domain with an inactivated, proprietary Fc domain, for hematologic and solid mal...

Product Name : ALX148

Product Type : Protein

Upfront Cash : Undisclosed

April 10, 2023

Lead Product(s) : Evorpacept,Ramucirumab

Therapeutic Area : Oncology

Highest Development Status : Phase II/ Phase III

Sponsor : Piper Sandler

Deal Size : Undisclosed

Deal Type : Public Offering

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07

Interphex
Not Confirmed
Interphex
Not Confirmed

Details : ALX148 (evorpacept) is a next generation CD47 blocker, which is being investigated in combination with trastuzumab in patients with HER2-positive gastric/gastroesophageal junction (“GEJ”) cancer.

Product Name : ALX148

Product Type : Protein

Upfront Cash : Inapplicable

March 10, 2023

Lead Product(s) : Evorpacept,Ramucirumab

Therapeutic Area : Oncology

Highest Development Status : Phase II/ Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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08

Peptide-Based Therapeutics Summit
Not Confirmed
Peptide-Based Therapeutics Summit
Not Confirmed

Details :

Product Name : Cyramza

Product Type : Antibody

Upfront Cash : Inapplicable

October 10, 2022

Lead Product(s) : Ramucirumab

Therapeutic Area : Oncology

Highest Development Status : Approved FDF

Sponsor : Eli Lilly

Deal Size : Inapplicable

Deal Type : Inapplicable

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09

Interphex
Not Confirmed
Interphex
Not Confirmed

Details : Under the terms of the agreement, upon regulatory approvals of Cyramza® in the hepatocellular carcinoma indication and Retsevmo® in the non-small lung cancer indication, and then intends to commercialize Cyramza® and Retsevmo® in China.

Product Name : Cyramza

Product Type : Antibody

Upfront Cash : Undisclosed

March 28, 2022

Lead Product(s) : Ramucirumab

Therapeutic Area : Oncology

Highest Development Status : Approved FDF

Sponsor : Innovent Biologics

Deal Size : $45.0 million

Deal Type : Partnership

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10

Interphex
Not Confirmed
Interphex
Not Confirmed

Details : Evorpacept used in combination with ramucirumab, trastuzumab, and paclitaxel demonstrated an initial confirmed objective response rate of 72.2% with a median duration of response of 14.8 months, a 12-month overall survival rate of 79%.

Product Name : ALX148

Product Type : Protein

Upfront Cash : Inapplicable

February 03, 2022

Lead Product(s) : Evorpacept,Ramucirumab

Therapeutic Area : Oncology

Highest Development Status : Phase II/ Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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