Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Semaglutide
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Rani Shows Preclinical Success for Oral Semaglutide via RaniPill® HC
Details : RaniPill HC (semaglutide) is an oral pill, which delivers glucagon-like peptide-1 (GLP-1) receptor agonist indicated for obesity.
Product Name : RaniPill HC
Product Type : Peptide
Upfront Cash : Inapplicable
February 05, 2025
Lead Product(s) : Semaglutide
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Rani Shares Data On Transenteric GLP-1 Incretin Triagonist Delivery
Details : An incretin triagonist GLP-1, GIP, glucagon receptors mimicking the RaniPill route of administration is being investigated for obesity.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Not Applicable
October 17, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : RT-114
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Preclinical
Sponsor : ProGen
Deal Size : Undisclosed
Deal Type : Partnership
Rani Therapeutics Announces Partnership with ProGen on Development of Obesity Treatment
Details : The partnership aims to develop and commercialization RT-114, an oral RaniPill capsule containing ProGen’s PG-102, a GLP-1/GLP-2 dual agonist, for the treatment of obesity
Product Name : RT-114
Product Type : Large molecule
Upfront Cash : Undisclosed
June 24, 2024
Lead Product(s) : RT-114
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Preclinical
Sponsor : ProGen
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : Ustekinumab
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Rani Reports Positive Phase 1 Results for Oral Anti-IL 12/23 Antibody RT-111
Details : RT-111 (ustekinumab-biosimilar) is an oral anti-IL 12/23 antibody in phase 1 trials for treating moderate to severe plaque psoriasis, Crohn’s, colitis, and active psoriatic arthritis.
Product Name : RT-111
Product Type : Large molecule
Upfront Cash : Not Applicable
February 05, 2024
Lead Product(s) : Ustekinumab
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Incretin-based Triagonist
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Incretin triagonist of the GLP-1, GIP, and glucagon receptors delivered transenterically, which mimics the RaniPill route of administration to enable oral delivery of multiple obesity treatments.
Product Name : Undisclosed
Product Type : Small molecule
Upfront Cash : Not Applicable
December 14, 2023
Lead Product(s) : Incretin-based Triagonist
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Adalimumab
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : RT-105 (adalimumab) is a monoclonal antibody which inhibits tumor necrosis factor. It binds specifically to TNF-alpha and blocks its interaction with the p55 and p75 cell surface TNF receptors.
Product Name : RT-105
Product Type : Large molecule
Upfront Cash : Not Applicable
October 19, 2023
Lead Product(s) : Adalimumab
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ustekinumab
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : RT-111 (ustekinumab) is an orally administered RaniPill®GO capsule containing an ustekinumab biosimilar that act as binds with specificity to the p40 protein subunit used by both the interleukin-12 and interleukin-23 for the treatment of psorasis.
Product Name : RT-111
Product Type : Large molecule
Upfront Cash : Not Applicable
September 18, 2023
Lead Product(s) : Ustekinumab
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Adalimumab
Therapeutic Area : Immunology
Study Phase : Preclinical
Recipient : Celltrion
Deal Size : Undisclosed
Deal Type : Partnership
Rani Therapeutics and Celltrion Expand Partnership to Include Adalimumab Biosimilar for RT-105
Details : Under the agreement, Celltrion will exclusively supply to Rani the adalimumab biosimilar drug substance (CT-P17) required for the development of RT-105, an oral capsule containing a TNF-α inhibitor antibody being developed for the treatment of psoriatic...
Product Name : RT-105
Product Type : Large molecule
Upfront Cash : Undisclosed
June 05, 2023
Lead Product(s) : Adalimumab
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Recipient : Celltrion
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : Ustekinumab
Therapeutic Area : Dermatology
Study Phase : Preclinical
Sponsor : Celltrion
Deal Size : Undisclosed
Deal Type : Partnership
Celltrion and Rani Therapeutics Partner on Development of Oral Monoclonal Antibody Treatment
Details : Rani is granted an exclusive license to use CT-P43 in the development and commercialization of RT-111, an orally administered ustekinumab biosimilar and Celltrion is granted a right of first negotiation to acquire worldwide rights to RT-111 following a P...
Product Name : RT-111
Product Type : Large molecule
Upfront Cash : Undisclosed
January 09, 2023
Lead Product(s) : Ustekinumab
Therapeutic Area : Dermatology
Highest Development Status : Preclinical
Sponsor : Celltrion
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : Teriparatide
Therapeutic Area : Musculoskeletal
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Rani Therapeutics Receives Feedback from Pre-IND Meeting with FDA; Provides Pipeline Update
Details : RT-102 (Parathyroid Hormone) is being developed for the treatment of osteoporosis. The study achieved all of its endpoints, with repeat doses of RT-102 being generally well tolerated and delivering drug with high reliability to participants via the RaniP...
Product Name : RT-102
Product Type : Peptide
Upfront Cash : Not Applicable
January 05, 2023
Lead Product(s) : Teriparatide
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable