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Find Clinical Drug Pipeline Developments & Deals by Ray Therapeutics

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The funding will be used to support development of RTx-021, an optogenetic therapy for the treatment of geographic atrophy (GA), the advanced form of age-related macular degeneration (AMD).

                          Brand Name : RTx-021

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          November 13, 2023

                          Lead Product(s) : RTx-021

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Discovery

                          Sponsor : CIRM

                          Deal Size : $4.0 million

                          Deal Type : Funding

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Under the agreement, Adverum grants Ray Therapeutics a worldwide, non-exclusive license of AAV.7m8 together with its RTx-015 asset, for the prevention, treatment, diagnosis or amelioration of any ocular disorder utilizing Ray’s optogenetics approach.

                          Brand Name : RTx-015

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          June 12, 2023

                          Lead Product(s) : RTx-015,AAV.7m8

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : IND Enabling

                          Recipient : Adverum Biotechnologies

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The financing will advance Ray Therapeutics’ optogenetics gene therapy programs for blinding retinal diseases including, RTx-015, a genotype agnostic, intended for use in treating patients with retinitis pigmentosa (RP).

                          Brand Name : RTx-015

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          May 16, 2023

                          Lead Product(s) : RTx-015

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : IND Enabling

                          Sponsor : Novo Holdings A/S

                          Deal Size : $100.0 million

                          Deal Type : Series A Financing

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                          04

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Forge will provide research-grade and GMP-Pathway plasmid manufacturing services, in addition to adeno-associated viral vector (AAV) process development, scale-up engineering, and cGMP manufacturing services for Ray Therapeutics’ program, RTx-015.

                          Brand Name : RTx-015

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          October 10, 2022

                          Lead Product(s) : RTx-015

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : IND Enabling

                          Sponsor : Forge Biologics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          05

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Funding will advance development of Ray Therapeutics’ optogenetics technology platform – Ray-001 for the treatment of Retinitis Pigmentosa. In preclinical studies, RAY-001 is intended to be a one-time treatment via intravitreal injection that is sust...

                          Brand Name : Ray-001

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          April 26, 2022

                          Lead Product(s) : Ray-001

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Preclinical

                          Sponsor : California Institute for Regenerative Medicine

                          Deal Size : $4.0 million

                          Deal Type : Funding

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                          06

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Ray-001 is intended for use in treating patients with retinitis pigmentosa (RP). Optogenetics is a promising approach that has the potential to restore useful vision to visually-impaired and blind individuals.

                          Brand Name : Ray-001

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          March 01, 2022

                          Lead Product(s) : Ray-001

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Preclinical

                          Sponsor : Forge Biologics

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          07

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The funding will be used to advance its optogenetic therapy, Ray-001, into clinical trials in retinitis pigmentosa (RP). Based on the durability of treatment demonstrated in preclinical studies, Ray-001 is intended to be a one-time treatment via intravit...

                          Brand Name : Ray-001

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          January 04, 2022

                          Lead Product(s) : Ray-001

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Preclinical

                          Sponsor : 4BIO Capital

                          Deal Size : $6.0 million

                          Deal Type : Financing

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