Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Actinium-225 Dotatate
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Bristol Myers Squibb
Deal Size : $4.1 million
Deal Type : Acquisition
Bristol Myers Squibb Acquires RayzeBio, Adding Actinium-Based Radiopharmaceuticals
Details : Bristol acquires RYZ101 (actinium-225 dotatate), targeting somatostatin receptor 2, currently evaluated for SSTR-positive gastroenteropancreatic neuroendocrine tumors.
Brand Name : RYZ101
Molecule Type : Small molecule
Upfront Cash : $4.1 million
February 26, 2024
Lead Product(s) : Actinium-225 Dotatate
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Bristol Myers Squibb
Deal Size : $4.1 million
Deal Type : Acquisition
Lead Product(s) : Actinium-225 Dotatate
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Bristol Myers Squibb
Deal Size : $4,100.0 million
Deal Type : Acquisition
Bristol Myers Squibb Adds Premier Radiopharmaceutical Platform with Acquisition of RayzeBio
Details : By acquiring RayzeBio’s differentiated actinium-based radiopharmaceutical platform, BMS will establish its presence in one of the most promising and fastest-growing new modalities for solid tumors, by delivering radioactive payloads to cancer cells in ...
Brand Name : RYZ101
Molecule Type : Small molecule
Upfront Cash : $4,100.0 million
December 26, 2023
Lead Product(s) : Actinium-225 Dotatate
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Bristol Myers Squibb
Deal Size : $4,100.0 million
Deal Type : Acquisition
Details : RYZ101 (Actinium-225 DOTATATE) is an investigational targeted radiopharmaceutical therapy, designed to deliver a highly potent radioisotope, Actinium-225 (Ac225), in patients with SSTR+ gastroenteropancreatic neuroendocrine tumors.
Brand Name : RYZ101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 24, 2023
Details : The proceeds will advance clinical development of RYZ101 (actinium-225 dotatate) in company's Phase 3 trial in GEP-NETs, RYZ101 through Phase 1b efficacy data in ES-SCLC and IND enabling activities and clinical development of RYZ801 and RYZ811 in HCC thr...
Brand Name : RYZ101
Molecule Type : Small molecule
Upfront Cash : Undisclosed
September 19, 2023
Lead Product(s) : RYZ801,Actinium-225
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : J.P. Morgan
Deal Size : Undisclosed
Deal Type : Public Offering
RayzeBio Announces Initial Public Offering
Details : The proceeds will advance IND enabling activities and clinical development of RYZ801, a novel proprietary peptide which targets GPC3 for delivery of Ac225, and RYZ811 in HCC through Phase 1b safety data and the development of RYZ101 for GEP-NETs and exte...
Brand Name : RYZ801
Molecule Type : Peptide
Upfront Cash : Undisclosed
August 25, 2023
Lead Product(s) : RYZ801,Actinium-225
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : J.P. Morgan
Deal Size : Undisclosed
Deal Type : Public Offering
Details : RYZ101 is an investigational targeted radiopharmaceutical therapy, designed to deliver a highly potent radioisotope, Actinium-225 (Ac225), in patients with SSTR+ gastroenteropancreatic neuroendocrine tumors.
Brand Name : RYZ101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 31, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Novel peptide drug candidate against GPC3 was nominated as GPC3 is selectively overexpressed in hepatocellular carcinoma and not expressed in normal liver and other tissues, making it the potential targeted cancer therapy.
Brand Name : Undisclosed
Molecule Type : Peptide
Upfront Cash : Not Applicable
March 21, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Actinium-225
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : RYZ101 is an investigational targeted radiopharmaceutical therapy, designed to deliver a highly potent radioisotope, Actinium-225 (Ac225), to tumors expressing SSTR2.
Brand Name : RYZ101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 20, 2023
Lead Product(s) : Actinium-225
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : RYZ101
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
RayzeBio Announces Issuance of Two Patents for RYZ101 (225Ac-DOTATATE)
Details : RYZ101 is an investigational targeted radiopharmaceutical therapy, designed to deliver a highly potent radioisotope, Actinium-225 (Ac225), to tumors expressing the somatostatin receptor type 2 (SSTR2).
Brand Name : RYZ101
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 04, 2023
Lead Product(s) : RYZ101
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : RYZ101
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Viking Global Investors
Deal Size : $160.0 million
Deal Type : Series D Financing
Details : RYZ101 is an investigational targeted radiopharmaceutical therapy, designed to deliver a highly potent radioisotope, Actinium-225 (Ac225), to tumors expressing the somatostatin receptor type 2 (SSTR2).
Brand Name : RYZ101
Molecule Type : Large molecule
Upfront Cash : Undisclosed
September 13, 2022
Lead Product(s) : RYZ101
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Viking Global Investors
Deal Size : $160.0 million
Deal Type : Series D Financing
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