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Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Bardoxolone Methyl","moa":"Nrf2","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Reata Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Reata Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Reata Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Reata Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Bardoxolone Methyl","moa":"Nrf2","graph1":"Nephrology","graph2":"Phase III","graph3":"Reata Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Reata Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Reata Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Reata Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Bardoxolone Methyl","moa":"Nrf2","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"Reata Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Reata Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Reata Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Reata Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Bardoxolone Methyl","moa":"Nrf2","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Reata Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Reata Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Reata Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Reata Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Omaveloxolone","moa":"Nrf2","graph1":"Genetic Disease","graph2":"Approved FDF","graph3":"Reata 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Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Reata Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Reata Pharmaceuticals \/ Inapplicable"}]

Find Clinical Drug Pipeline Developments & Deals by Reata Pharmaceuticals

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01

Plastics Recycling EU
Not Confirmed
Plastics Recycling EU
Not Confirmed

Details : Through the acquisition, Biogen bolster its neuromuscular and rare disease portfolio by gaining FDA-approved Skyclarys (omaveloxolone), the first and only approved treatment for Friedreich’s ataxia (FA) in the United States.

Product Name : RTA 408

Product Type : Other Small Molecule

Upfront Cash : $7,300.0 million

September 26, 2023

Lead Product(s) : Omaveloxolone

Therapeutic Area : Genetic Disease

Highest Development Status : Approved FDF

Sponsor : Biogen

Deal Size : $7,300.0 million

Deal Type : Acquisition

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02

Plastics Recycling EU
Not Confirmed
Plastics Recycling EU
Not Confirmed

Details : Through the acquisition, Biogen bolster its neuromuscular and rare disease portfolio by gaining FDA-approved Skyclarys (omaveloxolone), the first and only approved treatment for Friedreich’s ataxia (FA) in the United States.

Product Name : RTA 408

Product Type : Other Small Molecule

Upfront Cash : $7,300.0 million

July 28, 2023

Lead Product(s) : Omaveloxolone

Therapeutic Area : Genetic Disease

Highest Development Status : Approved FDF

Sponsor : Biogen

Deal Size : $7,300.0 million

Deal Type : Acquisition

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03

Plastics Recycling EU
Not Confirmed
Plastics Recycling EU
Not Confirmed

Details : Skyclarys™ (omaveloxolone) have been shown to activate the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathways and indicated for the treatment of Friedreich’s ataxia in adults and adolescents aged 16 years and older.

Product Name : RTA 408

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

June 27, 2023

Lead Product(s) : Omaveloxolone

Therapeutic Area : Genetic Disease

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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04

Plastics Recycling EU
Not Confirmed
Plastics Recycling EU
Not Confirmed

Details : Skyclarys™ (omaveloxolone) have been shown to activate the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathways and indicated for the treatment of Friedreich’s ataxia in adults and adolescents aged 16 years and older.

Product Name : RTA 408

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

June 15, 2023

Lead Product(s) : Omaveloxolone

Therapeutic Area : Genetic Disease

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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05

Plastics Recycling EU
Not Confirmed
Plastics Recycling EU
Not Confirmed

Details : Skyclarys™ (omaveloxolone) have been shown to activate the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway in vitro and in vivo in animals and humans. The Nrf2 pathway is involved in the cellular response to oxidative stress.

Product Name : RTA 408

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

February 28, 2023

Lead Product(s) : Omaveloxolone

Therapeutic Area : Genetic Disease

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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06

Plastics Recycling EU
Not Confirmed
Plastics Recycling EU
Not Confirmed

Details : Omaveloxolone is an investigational, oral, once-daily activator of Nrf2, a transcription factor that induces molecular pathways that promote resolution of inflammation by restoring mitochondrial function, reducing oxidative stress, and inhibiting pro-inf...

Product Name : RTA 408

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

October 13, 2022

Lead Product(s) : Omaveloxolone

Therapeutic Area : Genetic Disease

Highest Development Status : Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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07

Plastics Recycling EU
Not Confirmed
Plastics Recycling EU
Not Confirmed

Details : RTA 408 (omaveloxolone) is investigational, oral, once-daily activator of Nrf2, transcription factor that induces molecular pathways that promote resolution of inflammation by restoring mitochondrial function, reducing oxidative stress, inhibiting pro-in...

Product Name : RTA 408

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

September 08, 2022

Lead Product(s) : Omaveloxolone

Therapeutic Area : Genetic Disease

Highest Development Status : Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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08

Plastics Recycling EU
Not Confirmed
Plastics Recycling EU
Not Confirmed

Details : RTA 408 (Omaveloxolone) is investigational, oral, once-daily activator of Nrf2, a transcription factor that induces molecular pathways that promote resolution of inflammation by restoring mitochondrial function, reducing oxidative stress, inhibiting pro-...

Product Name : RTA 408

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

May 26, 2022

Lead Product(s) : Omaveloxolone

Therapeutic Area : Genetic Disease

Highest Development Status : Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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09

Plastics Recycling EU
Not Confirmed
Plastics Recycling EU
Not Confirmed

Details : Bardoxolone is orally administered activator of Nrf2, a transcription factor that induces molecular pathways that promote the resolution of inflammation by restoring mitochondrial function, reducing oxidative stress, and inhibiting pro-inflammatory signa...

Product Name : RTA 402

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

February 25, 2022

Lead Product(s) : Bardoxolone Methyl

Therapeutic Area : Nephrology

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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10

Plastics Recycling EU
Not Confirmed
Plastics Recycling EU
Not Confirmed

Details : Omaveloxolone is an investigational, oral, once-daily, activator of Nrf2, a transcription factor that induces molecular pathways that promote the resolution of inflammation by restoring mitochondrial function, reducing oxidative stress, & inhibiting pro-...

Product Name : RTA 408

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

January 04, 2022

Lead Product(s) : Omaveloxolone

Therapeutic Area : Genetic Disease

Highest Development Status : Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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