Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : RCT2100
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ReCode Doses First Patient in Phase 1b Study Of RCT2100 For Cystic Fibrosis
Details : RCT2100 is an investigational inhaled mRNA therapy, which is currently being evaluated for the treatment of patients with cystic fibrosis.
Brand Name : RCT2100
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 26, 2024
Lead Product(s) : RCT2100
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : RCT1100
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ReCode Receives FDA Orphan Drug Designation for RCT1100 in Primary Ciliary Dyskinesia
Details : RCT1100 is an inhaled mRNA therapy designed to deliver and express DNAI1 mRNA in target cells. It is under phase 1 clinical development for the treatment of Primary Ciliary Dyskinesia.
Brand Name : RCT1100
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 27, 2024
Lead Product(s) : RCT1100
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : RCT2100
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ReCode Doses First Participants in Phase 1 Study of Inhaled mRNA for Cystic Fibrosis
Details : RCT2100 is an inhaled mRNA-based therapy developed using our novel SORT lipid nanoparticle delivery platform. It is being developed for the treatment of cystic fibrosis.
Brand Name : RCT2100
Molecule Type : Large molecule
Upfront Cash : Not Applicable
February 21, 2024
Lead Product(s) : RCT2100
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CRISPR-based Therapy
Therapeutic Area : Genetic Disease
Study Phase : Discovery Platform
Recipient : Intellia Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Intellia and ReCode Collaborate On Gene Editing Therapies for Cystic Fibrosis
Details : The collaboration combines Intellia’s CRISPR platform and ReCode’s selective Organ Targeting lipid nanoparticle to correct cystic fibrosis-causing gene mutations.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
February 15, 2024
Lead Product(s) : CRISPR-based Therapy
Therapeutic Area : Genetic Disease
Highest Development Status : Discovery Platform
Recipient : Intellia Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : RCT1100
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ReCode Doses First Patient in Phase 1 of mRNA Therapy for Primary Ciliary Dyskinesia
Details : RCT1100 is an inhaled mRNA therapy designed to deliver and express DNAI1 mRNA in target cells. It is under phase 1 clinical development for the treatment of Primary Ciliary Dyskinesia.
Brand Name : RCT1100
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 03, 2024
Lead Product(s) : RCT1100
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : RCT1100
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I
Sponsor : Bioluminescence Ventures
Deal Size : $260.0 million
Deal Type : Series B Financing
ReCode Therapeutics Announces Closing of Extension to Series B Financing
Details : The proceeds will advance ReCode’s proprietary Selective Organ Targeting lipid nanoparticle pipeline, including Phase 1 trial of RCT1100 for primary ciliary dyskinesia and RCT2100, its cystic fibrosis candidate.
Brand Name : RCT1100
Molecule Type : Large molecule
Upfront Cash : Undisclosed
September 19, 2023
Lead Product(s) : RCT1100
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I
Sponsor : Bioluminescence Ventures
Deal Size : $260.0 million
Deal Type : Series B Financing
Lead Product(s) : RCT1100
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : RCT1100 is a first-in-class, mRNA-based genetic medicine for the treatment of people with primary ciliary dyskinesia (PCD) caused by pathogenic mutations in the DNAI1 gene that encodes a protein essential for ciliary movement.
Brand Name : RCT1100
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 15, 2023
Lead Product(s) : RCT1100
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : mRNA-based Therapy
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : The Cystic Fibrosis Foundation
Deal Size : $15.0 million
Deal Type : Funding
Details : ReCode is developing an inhaled ARCT-032 (mRNA therapy), designed to provide a correct copy of the cystic fibrosis transmembrane conductance regulator (CFTR) mRNA to lung cells to make a functional CFTR protein.
Brand Name : ARCT-032
Molecule Type : Large molecule
Upfront Cash : Undisclosed
January 10, 2023
Lead Product(s) : mRNA-based Therapy
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : The Cystic Fibrosis Foundation
Deal Size : $15.0 million
Deal Type : Funding
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Study Phase : Discovery Platform
Recipient : AskBio
Deal Size : Undisclosed
Deal Type : Collaboration
Details : AskBio will combine its synthetic DNA and gene editing nucleases with ReCode's selective organ targeting LNP technology to potentially create an all-in-one solution that enables full gene insertion by delivering with precision both the gene editing tool ...
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
January 09, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Highest Development Status : Discovery Platform
Recipient : AskBio
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : SORT LNP-based DNAI1 mRNA Therapeutic
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Preclinical
Sponsor : Leaps by Bayer
Deal Size : $200.0 million
Deal Type : Series B Financing
Details : Proceeds from the financing will be used to fund the diversification of ReCode’s pipeline into central nervous system, liver, and oncology indications, while continuing to advance lead mRNA programs for primary ciliary dyskinesia and cystic fibrosis in...
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
June 29, 2022
Lead Product(s) : SORT LNP-based DNAI1 mRNA Therapeutic
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Preclinical
Sponsor : Leaps by Bayer
Deal Size : $200.0 million
Deal Type : Series B Financing
LOOKING FOR A SUPPLIER?