Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Gene Correction Therapy
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Cystic Fibrosis Foundation
Deal Size : $15.0 million
Deal Type : Funding
ReCode Receives Cystic Fibrosis Foundation Funding for Gene Correction Therapies
Details : The proceeds will be used to accelerate ReCode’s gene correction research program with the goal of developing and commercializing new treatments for people with cystic fibrosis.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
November 18, 2024
Lead Product(s) : Gene Correction Therapy
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Cystic Fibrosis Foundation
Deal Size : $15.0 million
Deal Type : Funding
Lead Product(s) : RCT2100
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ReCode Doses First Patient in Phase 1b Study Of RCT2100 For Cystic Fibrosis
Details : RCT2100 is an investigational inhaled mRNA therapy, which is currently being evaluated for the treatment of patients with cystic fibrosis.
Brand Name : RCT2100
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 26, 2024
Lead Product(s) : RCT2100
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : RCT1100
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ReCode Receives FDA Orphan Drug Designation for RCT1100 in Primary Ciliary Dyskinesia
Details : RCT1100 is an inhaled mRNA therapy designed to deliver and express DNAI1 mRNA in target cells. It is under phase 1 clinical development for the treatment of Primary Ciliary Dyskinesia.
Brand Name : RCT1100
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 27, 2024
Lead Product(s) : RCT1100
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : RCT2100
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ReCode Doses First Participants in Phase 1 Study of Inhaled mRNA for Cystic Fibrosis
Details : RCT2100 is an inhaled mRNA-based therapy developed using our novel SORT lipid nanoparticle delivery platform. It is being developed for the treatment of cystic fibrosis.
Brand Name : RCT2100
Molecule Type : Large molecule
Upfront Cash : Not Applicable
February 21, 2024
Lead Product(s) : RCT2100
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CRISPR-based Therapy
Therapeutic Area : Genetic Disease
Study Phase : Discovery Platform
Recipient : Intellia Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Intellia and ReCode Collaborate On Gene Editing Therapies for Cystic Fibrosis
Details : The collaboration combines Intellia’s CRISPR platform and ReCode’s selective Organ Targeting lipid nanoparticle to correct cystic fibrosis-causing gene mutations.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
February 15, 2024
Lead Product(s) : CRISPR-based Therapy
Therapeutic Area : Genetic Disease
Highest Development Status : Discovery Platform
Recipient : Intellia Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : RCT1100
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ReCode Doses First Patient in Phase 1 of mRNA Therapy for Primary Ciliary Dyskinesia
Details : RCT1100 is an inhaled mRNA therapy designed to deliver and express DNAI1 mRNA in target cells. It is under phase 1 clinical development for the treatment of Primary Ciliary Dyskinesia.
Brand Name : RCT1100
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 03, 2024
Lead Product(s) : RCT1100
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : RCT1100
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I
Sponsor : Bioluminescence Ventures
Deal Size : $260.0 million
Deal Type : Series B Financing
ReCode Therapeutics Announces Closing of Extension to Series B Financing
Details : The proceeds will advance ReCode’s proprietary Selective Organ Targeting lipid nanoparticle pipeline, including Phase 1 trial of RCT1100 for primary ciliary dyskinesia and RCT2100, its cystic fibrosis candidate.
Brand Name : RCT1100
Molecule Type : Large molecule
Upfront Cash : Undisclosed
September 19, 2023
Lead Product(s) : RCT1100
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I
Sponsor : Bioluminescence Ventures
Deal Size : $260.0 million
Deal Type : Series B Financing
Lead Product(s) : RCT1100
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : RCT1100 is a first-in-class, mRNA-based genetic medicine for the treatment of people with primary ciliary dyskinesia (PCD) caused by pathogenic mutations in the DNAI1 gene that encodes a protein essential for ciliary movement.
Brand Name : RCT1100
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 15, 2023
Lead Product(s) : RCT1100
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : mRNA-based Therapy
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : The Cystic Fibrosis Foundation
Deal Size : $15.0 million
Deal Type : Funding
Details : ReCode is developing an inhaled ARCT-032 (mRNA therapy), designed to provide a correct copy of the cystic fibrosis transmembrane conductance regulator (CFTR) mRNA to lung cells to make a functional CFTR protein.
Brand Name : ARCT-032
Molecule Type : Large molecule
Upfront Cash : Undisclosed
January 10, 2023
Lead Product(s) : mRNA-based Therapy
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : The Cystic Fibrosis Foundation
Deal Size : $15.0 million
Deal Type : Funding
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Study Phase : Discovery Platform
Recipient : AskBio
Deal Size : Undisclosed
Deal Type : Collaboration
Details : AskBio will combine its synthetic DNA and gene editing nucleases with ReCode's selective organ targeting LNP technology to potentially create an all-in-one solution that enables full gene insertion by delivering with precision both the gene editing tool ...
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
January 09, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Highest Development Status : Discovery Platform
Recipient : AskBio
Deal Size : Undisclosed
Deal Type : Collaboration
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