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Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"ReCode Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"14","companyTruncated":"ReCode Therapeutics \/ Not Applicable"}]

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : RCT2100 is an investigational inhaled mRNA therapy, which is currently being evaluated for the treatment of patients with cystic fibrosis.

                          Brand Name : RCT2100

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 26, 2024

                          Lead Product(s) : RCT2100

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : RCT1100 is an inhaled mRNA therapy designed to deliver and express DNAI1 mRNA in target cells. It is under phase 1 clinical development for the treatment of Primary Ciliary Dyskinesia.

                          Brand Name : RCT1100

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 27, 2024

                          Lead Product(s) : RCT1100

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : RCT2100 is an inhaled mRNA-based therapy developed using our novel SORT lipid nanoparticle delivery platform. It is being developed for the treatment of cystic fibrosis.

                          Brand Name : RCT2100

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          February 21, 2024

                          Lead Product(s) : RCT2100

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : The collaboration combines Intellia’s CRISPR platform and ReCode’s selective Organ Targeting lipid nanoparticle to correct cystic fibrosis-causing gene mutations.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          February 15, 2024

                          Lead Product(s) : CRISPR-based Therapy

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Discovery Platform

                          Recipient : Intellia Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          05

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : RCT1100 is an inhaled mRNA therapy designed to deliver and express DNAI1 mRNA in target cells. It is under phase 1 clinical development for the treatment of Primary Ciliary Dyskinesia.

                          Brand Name : RCT1100

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          January 03, 2024

                          Lead Product(s) : RCT1100

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : The proceeds will advance ReCode’s proprietary Selective Organ Targeting lipid nanoparticle pipeline, including Phase 1 trial of RCT1100 for primary ciliary dyskinesia and RCT2100, its cystic fibrosis candidate.

                          Brand Name : RCT1100

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          September 19, 2023

                          Lead Product(s) : RCT1100

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase I

                          Sponsor : Bioluminescence Ventures

                          Deal Size : $260.0 million

                          Deal Type : Series B Financing

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                          07

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : RCT1100 is a first-in-class, mRNA-based genetic medicine for the treatment of people with primary ciliary dyskinesia (PCD) caused by pathogenic mutations in the DNAI1 gene that encodes a protein essential for ciliary movement.

                          Brand Name : RCT1100

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 15, 2023

                          Lead Product(s) : RCT1100

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : ReCode is developing an inhaled ARCT-032 (mRNA therapy), designed to provide a correct copy of the cystic fibrosis transmembrane conductance regulator (CFTR) mRNA to lung cells to make a functional CFTR protein.

                          Brand Name : ARCT-032

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          January 10, 2023

                          Lead Product(s) : mRNA-based Therapy

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Preclinical

                          Sponsor : The Cystic Fibrosis Foundation

                          Deal Size : $15.0 million

                          Deal Type : Funding

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                          09

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : AskBio will combine its synthetic DNA and gene editing nucleases with ReCode's selective organ targeting LNP technology to potentially create an all-in-one solution that enables full gene insertion by delivering with precision both the gene editing tool ...

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          January 09, 2023

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Technology

                          Highest Development Status : Discovery Platform

                          Recipient : AskBio

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          10

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : Proceeds from the financing will be used to fund the diversification of ReCode’s pipeline into central nervous system, liver, and oncology indications, while continuing to advance lead mRNA programs for primary ciliary dyskinesia and cystic fibrosis in...

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          June 29, 2022

                          Lead Product(s) : SORT LNP-based DNAI1 mRNA Therapeutic

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Preclinical

                          Sponsor : Leaps by Bayer

                          Deal Size : $200.0 million

                          Deal Type : Series B Financing

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