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Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2025","type":"Inapplicable","leadProduct":"Linvoseltamab","moa":"B-cell maturation antigen","graph1":"Oncology","graph2":"Phase III","graph3":"Regeneron Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Regeneron Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Regeneron Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Regeneron Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2025","type":"Inapplicable","leadProduct":"Linvoseltamab","moa":"B-cell maturation antigen","graph1":"Oncology","graph2":"Phase III","graph3":"Regeneron Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Regeneron Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Regeneron Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Regeneron Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Other Large Molecule","year":"2024","type":"Inapplicable","leadProduct":"REGN7508","moa":"Factor XI","graph1":"Hematology","graph2":"Phase II","graph3":"Regeneron Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Regeneron Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Regeneron Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Regeneron Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Protein","year":"2025","type":"Inapplicable","leadProduct":"Aflibercept","moa":"VEGF-A\/PlGF","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Regeneron Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Regeneron Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Regeneron Pharmaceuticals \/ Inapplicable"}]

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                            01

                            Regeneron Pharmaceuticals

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                            Lead Product(s) : Aflibercept

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            EYLEA HD Injection 8 mg Accepted for FDA Priority Review in RVO and Monthly Dosing

                            Details : Eylea HD (aflibercept) is a PIGF & VEGF-A inhibitor, being investigated for the treatment of macular edema following retinal vein occlusion.

                            Product Name : Eylea HD

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            April 17, 2025

                            Lead Product(s) : Aflibercept

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Regeneron Pharmaceuticals

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                            Lead Product(s) : Dupilumab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Approved FDF

                            Sponsor : Sanofi

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Dupixent Approved In Japan As First Biologic for COPD Treatment

                            Details : Dupixent (dupilumab) is an approved monoclonal antibody works by inhibiting IL-4 and IL-13. It is given subcutaneously for the treatment of uncontrolled COPD in adults with raised blood eosinophils.

                            Product Name : Dupixent

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            March 28, 2025

                            Lead Product(s) : Dupilumab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Sanofi

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Regeneron Pharmaceuticals

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                            MAGHREB PHARMA
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                            Lead Product(s) : Linvoseltamab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Linvoseltamab Recommended for EU Approval for Relapsed Multiple Myeloma

                            Details : REGN5458 (linvoseltamab) is an antibody infusion therapy inhibiting BCMA/CD3, it is currently being investigated for the treatment of relapsed/refractory multiple myeloma.

                            Product Name : REGN5458

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            February 28, 2025

                            Lead Product(s) : Linvoseltamab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Regeneron Pharmaceuticals

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                            MAGHREB PHARMA
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                            Regeneron Pharmaceuticals

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                            MAGHREB PHARMA
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                            Lead Product(s) : Odronextamab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Odronextamab BLA Accepted for FDA Review in Relapsed/Refractory Lymphoma

                            Details : Ordspono (odronextamab) is a novel, CD20×CD3 bispecific antibody, which is being evaluated for the treatment of relapsed/refractory follicular lymphoma after two or more lines of systemic therapy.

                            Product Name : Ordspono

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            February 26, 2025

                            Lead Product(s) : Odronextamab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Regeneron Pharmaceuticals

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                            MAGHREB PHARMA
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                            Regeneron Pharmaceuticals

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                            MAGHREB PHARMA
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                            Lead Product(s) : Otoferlin

                            Therapeutic Area : Otolaryngology (Ear, Nose, Throat)

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            DB-OTO Shows Hearing Gains in CHORD Trial for Children

                            Details : DB-OTO is a cell-selective, AAV-gene therapy designed to provide durable, physiological hearing to individuals with profound, congenital hearing loss caused by variants of the otoferlin gene.

                            Product Name : DB-OTO

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            February 24, 2025

                            Lead Product(s) : Otoferlin

                            Therapeutic Area : Otolaryngology (Ear, Nose, Throat)

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Regeneron Pharmaceuticals

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                            MAGHREB PHARMA
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                            Regeneron Pharmaceuticals

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                            MAGHREB PHARMA
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                            Lead Product(s) : Linvoseltamab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Linvoseltamab BLA Accepted for FDA Review in R/R Multiple Myeloma Treatment

                            Details : REGN5458 (linvoseltamab) is an antibody infusion therapy inhibiting BCMA/CD3, it is currently being investigated for the treatment of relapsed/refractory multiple myeloma.

                            Product Name : REGN5458

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            February 11, 2025

                            Lead Product(s) : Linvoseltamab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Regeneron Pharmaceuticals

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                            MAGHREB PHARMA
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                            Regeneron Pharmaceuticals

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                            MAGHREB PHARMA
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                            Lead Product(s) : Cemiplimab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Libtayo® Improves DFS in CSCC after Surgery in Phase 3 Trial

                            Details : Libtayo (cemiplimab) is a fully human monoclonal antibody targeting the immune checkpoint receptor PD-1. It block cancer cells from using the PD-1 pathway to suppress T-cell activation.

                            Product Name : Libtayo

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            January 13, 2025

                            Lead Product(s) : Cemiplimab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Regeneron Pharmaceuticals

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                            MAGHREB PHARMA
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                            Regeneron Pharmaceuticals

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                            MAGHREB PHARMA
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                            Lead Product(s) : REGN7508

                            Therapeutic Area : Hematology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Regeneron to Advance Factor XI Antibodies Into Phase 3 Program

                            Details : REGN7508 is an antibody designed to maximize anticoagulant activity while minimizing bleeding risk, in patients with venous thromboembolism.

                            Product Name : REGN7508

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            December 19, 2024

                            Lead Product(s) : REGN7508

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Regeneron Pharmaceuticals

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                            MAGHREB PHARMA
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                            Regeneron Pharmaceuticals

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                            MAGHREB PHARMA
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                            Lead Product(s) : Pozelimab,Cemdisiran,Ravulizumab

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Poze-Cemdi Combo Controls Intravascular Hemolysis in PNH Patients Vs Ravulizumab

                            Details : Veopoz (pozelimab) is a complement C5 inhibitor antibody, which is being evaluated in combination with cemdisiran for the treatment of paroxysmal nocturnal hemoglobinuria.

                            Product Name : Veopoz

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            December 07, 2024

                            Lead Product(s) : Pozelimab,Cemdisiran,Ravulizumab

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Regeneron Pharmaceuticals

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                            MAGHREB PHARMA
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                            Regeneron Pharmaceuticals

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                            MAGHREB PHARMA
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                            Lead Product(s) : Dupilumab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase III

                            Sponsor : Sanofi

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Dupixent Confirm Improvements in Itch and Hives for Chronic Spontaneous Urticaria Patients

                            Details : Dupixent (dupilumab) is a monoclonal antibody that inhibits the signaling of the IL-4 and IL-13 pathways. It is being evaluated for chronic obstructive pulmonary disease with type 2 inflammation.

                            Product Name : Dupixent

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            November 09, 2024

                            Lead Product(s) : Dupilumab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase III

                            Sponsor : Sanofi

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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