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Pharmaceuticals \/ Sanofi"},{"orgOrder":0,"company":"Regeneron Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Aflibercept","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Regeneron Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Regeneron Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"14","companyTruncated":"Regeneron Pharmaceuticals \/ Not Applicable"},{"orgOrder":0,"company":"Regeneron Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Dupilumab","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Regeneron Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Regeneron Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"14","companyTruncated":"Regeneron Pharmaceuticals \/ Not Applicable"}]

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                            01

                            Regeneron Pharmaceuticals

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                            Lead Product(s) : Dupilumab

                            Therapeutic Area : Immunology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Dupixent® Approved for Young Children with Eosinophilic Esophagitis

                            Details : Dupixent (dupilumab) is a fully human mAb that inhibits the signaling of the IL-4/IL-13 pathways. It is approved to treat eosinophilic esophagitis in children as young as 1 year of age.

                            Brand Name : Dupixent

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            November 06, 2024

                            Lead Product(s) : Dupilumab

                            Therapeutic Area : Immunology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Regeneron Pharmaceuticals

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                            Lead Product(s) : Aflibercept

                            Therapeutic Area : Ophthalmology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            EYLEA HD® Shows Durable Vision Gains in Diabetic Macular Edema

                            Details : Eylea HD (aflibercept) is a vascular endothelial growth factor (VEGF) inhibitor indicated for the treatment of patients with Diabetic Macular Edema.

                            Brand Name : Eylea HD

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            October 18, 2024

                            Lead Product(s) : Aflibercept

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Regeneron Pharmaceuticals

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                            Lead Product(s) : Dupilumab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Approved

                            Sponsor : Sanofi

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Dupixent® Approved in the U.S. as the First Biologic for COPD Patients

                            Details : Dupixent (dupilumab) is an approved monoclonal antibody works by inhibiting IL-4 and IL-13. It is given subcutaneously for the treatment of uncontrolled COPD in adults with raised blood eosinophils.

                            Brand Name : Dupixent

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 27, 2024

                            Lead Product(s) : Dupilumab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Approved

                            Sponsor : Sanofi

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Regeneron Pharmaceuticals

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                            Lead Product(s) : Dupilumab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase III

                            Sponsor : Sanofi

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Dupixent Confirm Improvements in Itch and Hives for Chronic Spontaneous Urticaria Patients

                            Details : Dupixent (dupilumab) is a monoclonal antibody that inhibits the signaling of the IL-4 and IL-13 pathways. It is being evaluated for chronic obstructive pulmonary disease with type 2 inflammation.

                            Brand Name : Dupixent

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 11, 2024

                            Lead Product(s) : Dupilumab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase III

                            Sponsor : Sanofi

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Regeneron Pharmaceuticals

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                            Lead Product(s) : Treg Cell Therapy

                            Therapeutic Area : Gastroenterology

                            Study Phase : Discovery

                            Recipient : Sonoma Biotherapeutics

                            Deal Size : $120.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Sonoma Biotherapeutics Receives $45M Regeneron Milestone

                            Details : The collaboration will bring together Regeneron’s VelociSuite technologies to discover, develop and commercialize engineered Treg therapies for autoimmune diseases.

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : $75.0 million

                            September 04, 2024

                            Lead Product(s) : Treg Cell Therapy

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Discovery

                            Recipient : Sonoma Biotherapeutics

                            Deal Size : $120.0 million

                            Deal Type : Collaboration

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                            06

                            Regeneron Pharmaceuticals

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                            Lead Product(s) : Odronextamab,Cyclophosphamide,Doxorubicin Hydrochloride

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Ordspono™ Approved in EU for Relapsed/Refractory Lymphoma Treatment

                            Details : Ordspono (odronextamab) is a novel, CD20×CD3 bispecific antibody, which is being evaluated for the treatment of relapsed/refractory follicular lymphoma and in R/R diffuse large B-cell lymphoma.

                            Brand Name : Ordspono

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            August 26, 2024

                            Lead Product(s) : Odronextamab,Cyclophosphamide,Doxorubicin Hydrochloride

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Regeneron Pharmaceuticals

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                            Lead Product(s) : Linvoseltamab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Regeneron Provides Update on Biologics License Application for Linvoseltamab

                            Details : REGN5458 (linvoseltamab) is an antibody infusion therapy inhibiting BCMA/CD3, it is currently being investigated for the treatment of relapsed/refractory multiple myeloma.

                            Brand Name : REGN5458

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            August 20, 2024

                            Lead Product(s) : Linvoseltamab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Regeneron Pharmaceuticals

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                            Lead Product(s) : Dupilumab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Approved

                            Sponsor : Sanofi

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Dupixent® Approved in EU as First Targeted Therapy for COPD

                            Details : Dupixent (dupilumab) is an approved monoclonal antibody works by inhibiting IL-4 and IL-13. It is given subcutaneously for the treatment of uncontrolled COPD in adults with raised blood eosinophils.

                            Brand Name : Dupixent

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            July 03, 2024

                            Lead Product(s) : Dupilumab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Approved

                            Sponsor : Sanofi

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Regeneron Pharmaceuticals

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                            Lead Product(s) : Odronextamab,Cyclophosphamide,Doxorubicin Hydrochloride

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Odronextamab Recommended for EU Approval to Treat Relapsed/Refractory Lymphoma

                            Details : REGN1979 (odronextamab) is a novel, CD20×CD3 bispecific antibody, which is being evaluated for the treatment of relapsed/refractory follicular lymphoma and in R/R diffuse large B-cell lymphoma.

                            Brand Name : REGN1979

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 28, 2024

                            Lead Product(s) : Odronextamab,Cyclophosphamide,Doxorubicin Hydrochloride

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Regeneron Pharmaceuticals

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                            Lead Product(s) : FG-3165,Cemiplimab

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : FibroGen

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            FibroGen, Regeneron Evaluate FG-3165, FG-3175 Plus LIBTAYO Combos

                            Details : The collaboration aims to focus on the development of FG-3165, a galectin-9 (Gal9) targeted antibody, combined with Libtayo for treating patients related to neoplasms.

                            Brand Name : FG-3165

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            June 03, 2024

                            Lead Product(s) : FG-3165,Cemiplimab

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : FibroGen

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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