Lead Product(s) : Relacorilant
Therapeutic Area : Endocrinology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Corcept Meets Primary Endpoint in Phase 3 GRACE Trial of Relacorilant in Cushing's
Details : CORT125134 (relacorilant) is a selective cortisol modulator that binds to the glucocorticoid receptor. It is being evaluated for the treatment of cushing’s syndrome.
Brand Name : CORT125134
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 28, 2024
Lead Product(s) : Relacorilant
Therapeutic Area : Endocrinology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Relacorilant
Therapeutic Area : Endocrinology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Corcept Reports Results from Phase 3 Grace Trial in Cushing Syndrome Patients
Details : CORT125134 (relacorilant), a selective cortisol modulator, is in trials for Cushing’s syndrome and is also being tested with nab-paclitaxel for platinum-resistant ovarian cancer.
Brand Name : CORT125134
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 22, 2024
Lead Product(s) : Relacorilant
Therapeutic Area : Endocrinology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Relacorilant,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Corcept Completes Enrollment in Phase 3 Rosella Trial for Relacorilant in Ovarian Cancer
Details : CORT125134 (relacorilant), a selective cortisol modulator, is in trials for Cushing’s syndrome and is also being tested with nab-paclitaxel for platinum-resistant ovarian cancer.
Brand Name : CORT125134
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 08, 2024
Lead Product(s) : Relacorilant,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Relacorilant
Therapeutic Area : Endocrinology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Corcept Completes Enrollment in Phase 3 Trial of Relacorilant for Cushing's Syndrome
Details : CORT125134 (relacorilant) is a selective cortisol modulator that binds to the glucocorticoid receptor. It is being evaluated for the treatment of adrenal cushing’s syndrome.
Brand Name : CORT125134
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 01, 2024
Lead Product(s) : Relacorilant
Therapeutic Area : Endocrinology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Relacorilant,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Phase 2 trial showed that CORT-125134 (relacorilant) plus nab-paclitaxel improved progression-free survival, duration of response and overall survival without an increased side effect burden compared to nab-paclitaxel alone.
Brand Name : CORT-125134
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 29, 2022
Lead Product(s) : Relacorilant,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Relacorilant,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : In Corcept’s Phase 2 trial, women who met the entry criteria for ROSELLA and received CORT-125134 (relacorilant) exhibited substantial benefit, without increasing the frequency or severity of adverse events.
Brand Name : CORT-125134
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 06, 2022
Lead Product(s) : Relacorilant,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Relacorilant,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Relacorilant is a non-steroidal, selective modulator of glucocorticoid receptor. Results show statistically significant and clinically benefit experienced by women with recurrent platinum-resistant ovarian cancer who were treated with nab-paclitaxel plus...
Brand Name : CORT-125134
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 17, 2021
Lead Product(s) : Relacorilant,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Relacorilant,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : RELIANT is a single-arm, multicenter, open-label, Phase 3 trial of relacorilant combined with nab-paclitaxel in patients with metastatic pancreatic cancer, with a planned enrollment of 80 patients and a planned interim analysis of outcomes in the first 4...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 22, 2021
Lead Product(s) : Relacorilant,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Relacorilant
Therapeutic Area : Endocrinology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : GRADIENT is a double-blind, placebo-controlled Phase 3 trial, with a planned enrollment of 130 patients at sites in the United States and Europe. Half of the patients will receive relacorilant and the other half placebo for six months.
Brand Name : CORT125134
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 28, 2020
Lead Product(s) : Relacorilant
Therapeutic Area : Endocrinology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Relacorilant,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Corcept completed enrollment in its controlled, Phase 2 trial of relacorilant combined with nab-paclitaxel (Abraxane®) in patients with metastatic, platinum-resistant ovarian cancer.
Brand Name : CORT125134
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 23, 2020
Lead Product(s) : Relacorilant,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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