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    [{"orgOrder":0,"company":"Relmada Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Methadone","moa":"NMDA","graph1":"Psychiatry\/Psychology","graph2":"Phase II","graph3":"Relmada Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Oral Solution","sponsorNew":"Relmada Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Relmada Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Relmada Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Methadone","moa":"NMDA","graph1":"Psychiatry\/Psychology","graph2":"Phase II","graph3":"Relmada 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    Find Clinical Drug Pipeline Developments & Deals by Relmada Therapeutics

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                            01

                            Relmada Therapeutics

                            U.S.A arrow
                            The Generic Rx Session
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                            Relmada Therapeutics

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                            The Generic Rx Session
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                            Lead Product(s) : Allopregnanolone

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Recipient : Asarina Pharma

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Relmada Acquires Tourette Therapy from Asarina Pharma

                            Details : Relmada acquires Isoallopregnanolone (sepranolone) from Asarina. Sepranolone is a first-in-class GABAA Modulating Steroid Antagonist (GAMSA), being evaluated for Tourette syndrome.

                            Product Name : Isoallopregnanolone

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            February 06, 2025

                            Lead Product(s) : Allopregnanolone

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Recipient : Asarina Pharma

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            02

                            Relmada Therapeutics

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed

                            Relmada Therapeutics

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed
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                            Lead Product(s) : Esmethadone Hydrochloride

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Relmada to Discontinue Reliance II and Relight Phase 3 Studies of REL-1017

                            Details : REL-1017 (esmethadone) NMDA receptor inhibitor, small molecule drug candidate, which is being evaluated as an adjunct treatment for the treatment of major depressive disorder.

                            Product Name : Undisclosed

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 09, 2024

                            Lead Product(s) : Esmethadone Hydrochloride

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Relmada Therapeutics

                            U.S.A arrow
                            The Generic Rx Session
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                            Relmada Therapeutics

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                            The Generic Rx Session
                            Not Confirmed
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                            Lead Product(s) : Esmethadone Hydrochloride

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Relmada Finds Phase 3 Reliance II Trial Futile At Interim Analysis

                            Details : REL-1017 is a NCE and novel NMDAR channel blocker that targets hyperactive channels while maintaining physiological glutamatergic neurotransmission, in major depressive disorder patients.

                            Product Name : Undisclosed

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 04, 2024

                            Lead Product(s) : Esmethadone Hydrochloride

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Relmada Therapeutics

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed

                            Relmada Therapeutics

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed
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                            Lead Product(s) : Psilocybine

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Relmada Therapeutics Initiates Phase 1 Dosing with REL-P11 for Metabolic Disease

                            Details : REL-P11 is a proprietary, low-dose, modified-release psilocybin formulation, being investigated for the treatment of obesity and other metabolic diseases.

                            Product Name : REL-P11

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 14, 2024

                            Lead Product(s) : Psilocybine

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Relmada Therapeutics

                            U.S.A arrow
                            The Generic Rx Session
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                            Relmada Therapeutics

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                            The Generic Rx Session
                            Not Confirmed
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                            Lead Product(s) : Esmethadone Hydrochloride

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Relmada Therapeutics Announces Top-line Results from Phase 3 RELIANCE I Trial for REL-1017 as an Adjunctive Tr...

                            Details : REL-1017, a new chemical entity and novel NMDA receptor channel blocker that preferentially targets hyperactive channels while maintaining physiological glutamatergic neurotransmission, is currently in late-stage development for the treatment of major de...

                            Product Name : REL-1017

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 07, 2022

                            Lead Product(s) : Esmethadone Hydrochloride

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Relmada Therapeutics

                            U.S.A arrow
                            The Generic Rx Session
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                            Relmada Therapeutics

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                            The Generic Rx Session
                            Not Confirmed
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                            Lead Product(s) : Esmethadone

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Relmada Therapeutics Announces Top-line Results from Phase 3 RELIANCE III Trial for REL-1017 as a Monotherapy ...

                            Details : In the study, the REL-1017 treatment arm showed a MADRS reduction of 14.8 points at Day 28 versus 13.9 points for the placebo arm, a higher than expected placebo response.

                            Product Name : REL-1017

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 13, 2022

                            Lead Product(s) : Esmethadone

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Relmada Therapeutics

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed

                            Relmada Therapeutics

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed
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                            Lead Product(s) : Esmethadone Hydrochloride

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Relmada Therapeutics to Present Data at the American Society of Clinical Psychopharmacology 2022 Annual Meetin...

                            Details : REL-1017 (esmethadone), new chemical entity and novel NMDA receptor channel blocker preferentially targets hyperactive channels while maintaining physiological glutamatergic neurotransmission, in late-stage development for treatment of major depressive d...

                            Product Name : REL-1017

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            May 25, 2022

                            Lead Product(s) : Esmethadone Hydrochloride

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Relmada Therapeutics

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed

                            Relmada Therapeutics

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed
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                            Lead Product(s) : Esmethadone Hydrochloride

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Relmada Therapeutics Announces Publication of REL-1017 Preclinical Data in Frontiers in Pharmacology

                            Details : REL-1017, a new chemical entity (NCE) and novel NMDA receptor (NMDAR) channel blocker that preferentially targets hyperactive channels while maintaining physiological glutamatergic neurotransmission, is currently in late-stage development for the treatme...

                            Product Name : REL-1017

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            April 29, 2022

                            Lead Product(s) : Esmethadone Hydrochloride

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Relmada Therapeutics

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed

                            Relmada Therapeutics

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed
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                            Lead Product(s) : Esmethadone Hydrochloride

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Relmada Therapeutics to Present Data at the Ketamine & Related Compounds International Hybrid Conference 2022

                            Details : REL-1017, a new chemical entity (NCE) and novel NMDA receptor (NMDAR) channel blocker that preferentially targets hyperactive channels while maintaining physiological glutamatergic neurotransmission, is currently in late-stage development for the treatme...

                            Product Name : REL-1017

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            April 04, 2022

                            Lead Product(s) : Esmethadone Hydrochloride

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Relmada Therapeutics

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                            The Generic Rx Session
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                            Relmada Therapeutics

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                            The Generic Rx Session
                            Not Confirmed
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                            Lead Product(s) : Methadone

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Relmada Results of Study Evaluating REL-1017 vs Oxycodone for Abuse Potential

                            Details : Top-line results showed that all three doses of REL-1017 (25 mg, 75 mg and 150 mg) tested in recreational opioid users, demonstrated a highly statistically significant difference vs. the active control drug, oxycodone 40 mg.

                            Product Name : REL-1017

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 27, 2021

                            Lead Product(s) : Methadone

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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