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                          Top Deals by Deal Size (USD bn)

                          01

                          euroPLX 86 Munich
                          Not Confirmed
                          euroPLX 86 Munich
                          Not Confirmed

                          Details : Orgovyx (relugolix) is a nonpeptide GnRH receptor antagonist. It is launched in Canada for testosterone suppression in patients with advanced prostate cancer.

                          Brand Name : Orgovyx

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 12, 2024

                          Lead Product(s) : Relugolix

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          euroPLX 86 Munich
                          Not Confirmed
                          euroPLX 86 Munich
                          Not Confirmed

                          Details : Rexigo (relugolix) is a nonpeptide GnRH receptor antagonist. It is launched in India for testosterone suppression in patients with advanced prostate cancer.

                          Brand Name : Rexigo

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          February 01, 2024

                          Lead Product(s) : Relugolix

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          euroPLX 86 Munich
                          Not Confirmed
                          euroPLX 86 Munich
                          Not Confirmed

                          Details : Ryeqo (relugolix, estradiol, and norethisterone acetate) receives approval from EU in for the adjuvant treatment of endometriosis in women with a history of previous medical or surgical treatment for their endometriosis.

                          Brand Name : Ryeqo

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 02, 2023

                          Lead Product(s) : Relugolix,Estradiol,Norethisterone Acetate

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          euroPLX 86 Munich
                          Not Confirmed
                          euroPLX 86 Munich
                          Not Confirmed

                          Details : ORGOVYX (relugolix), is the first and only oral gonadotropin-releasing hormone (GnRH) receptor antagonist, for the treatment of men with advanced prostate cancer.

                          Brand Name : Orgovyx

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 24, 2023

                          Lead Product(s) : Relugolix

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          euroPLX 86 Munich
                          Not Confirmed
                          euroPLX 86 Munich
                          Not Confirmed

                          Details : Orogvyx (relugolix), is the first and only oral gonadotropin-releasing hormone (GnRH) receptor antagonist, for the treatment of men with advanced prostate cancer.

                          Brand Name : Orgovyx

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 23, 2023

                          Lead Product(s) : Relugolix

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          euroPLX 86 Munich
                          Not Confirmed
                          euroPLX 86 Munich
                          Not Confirmed

                          Details : Myfembree (relugolix, estradiol, and norethindrone acetate) has received a dual indication approval, making it the first Health Canada-approved oral treatment to manage uterine fibroids and endometriosis.

                          Brand Name : Myfembree

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 19, 2023

                          Lead Product(s) : Relugolix,Estradiol,Norethisterone Acetate

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Approved

                          Sponsor : Pfizer Inc

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          euroPLX 86 Munich
                          Not Confirmed
                          euroPLX 86 Munich
                          Not Confirmed

                          Details : Ryeqo (relugolix, estradiol, and norethisterone acetate) receives positive opinion by CHMP recommending approval in for the adjuvant treatment of endometriosis in women with a history of previous medical or surgical treatment for their endometriosis.

                          Brand Name : Ryeqo

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 15, 2023

                          Lead Product(s) : Relugolix,Estradiol,Norethisterone Acetate

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Phase III

                          Sponsor : Sumitomo

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          euroPLX 86 Munich
                          Not Confirmed
                          euroPLX 86 Munich
                          Not Confirmed

                          Details : Sumitovant and Myovant will strengthen Myovant's two products, Orgovyx® (relugolix) and Myfembree® capabilities and help continue to deliver innovative therapies addressing unmet patient needs in prostate cancer and women's health.

                          Brand Name : Orgovyx

                          Molecule Type : Small molecule

                          Upfront Cash : $1,700.0 million

                          March 10, 2023

                          Lead Product(s) : Relugolix

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Sumitovant Biopharma

                          Deal Size : $1,700.0 million

                          Deal Type : Acquisition

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                          09

                          euroPLX 86 Munich
                          Not Confirmed
                          euroPLX 86 Munich
                          Not Confirmed

                          Details : Orgovyx (relugolix), was granted approval by the European Medicines Agency (EMA) in April 2022 for the treatment of adult patients with advanced hormone-sensitive prostate cancer.

                          Brand Name : Orgovyx

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 20, 2022

                          Lead Product(s) : Relugolix

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          euroPLX 86 Munich
                          Not Confirmed
                          euroPLX 86 Munich
                          Not Confirmed

                          Details : Sumitovant and Myovant will strengthen Myovant's two products, Orgovyx® (relugolix) and Myfembree® capabilities and help continue to deliver innovative therapies addressing unmet patient needs in prostate cancer and women's health.

                          Brand Name : Orgovyx

                          Molecule Type : Small molecule

                          Upfront Cash : $1,700.0 million

                          October 23, 2022

                          Lead Product(s) : Relugolix

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Sumitovant Biopharma

                          Deal Size : $1,700.0 million

                          Deal Type : Acquisition

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