Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Telitacicept
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
RemeGen Completes Enrollment in Phase III Trials of Telitacicept for IgA Nephropathy
Details : RC18 (telitacicept) targets BLyS and a proliferation inducing ligand, which allows it to effectively reduce B-cell mediated autoimmune responses that are implicated in autoimmune diseases like IgAN.
Brand Name : RC18
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 21, 2024
Lead Product(s) : Telitacicept
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Telitacicept
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
RemeGen's Telitacicept Granted Fast Track Designation for Primary Sjögren's Syndrome
Details : RC18 (telitacicept) targets BLyS and APRIL, two critical molecules for B-cell development, effectively reducing autoimmune responses in several autoimmune diseases by modulating B-cell activity.
Brand Name : RC18
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 02, 2024
Lead Product(s) : Telitacicept
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
RemeGen's RC88 Obtains FDA Fast Track Designation for Ovarian Cancer Treatment
Details : RC88 is a mesothelin-targeting ADC in phase 2 trials for treating platinum-resistant recurrent ovarian, fallopian tube, and primary peritoneal cancers.
Brand Name : RC88
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 12, 2024
Lead Product(s) : RC88,Sintilimab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Innovent Biologics
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration will focus on conducting clinical trials exploring combination therapies of the novel antibody-drug conjugates, RC88 (targeting MSLN) and RC108 (targeting c-MET), along with the PD-1 inhibitor sintilimab injection (TYVYT®).
Brand Name : RC88
Molecule Type : Large molecule
Upfront Cash : Undisclosed
July 09, 2023
Lead Product(s) : RC88,Sintilimab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Innovent Biologics
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : RC88,Sintilimab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Innovent Biologics
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the agreement, Innovent will provide supplies of TYVYT® (sintilimab injection) and RemeGen will conduct Phase 1/2a studies to evaluate the anti-tumor activity of the combination therapy of TYVYT® with RC88 or RC108 in Chinese patients with advanc...
Brand Name : RC88
Molecule Type : Large molecule
Upfront Cash : Undisclosed
June 25, 2023
Lead Product(s) : RC88,Sintilimab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Innovent Biologics
Deal Size : Undisclosed
Deal Type : Collaboration
Details : RC118 is RemeGen's latest advanced antibody-drug conjugate used to treat patients with solid tumors positive for Claudin 18.2 expressions. ADC product pipeline, with no less than four products, including the latest RC118, entering clinical trials or gain...
Brand Name : RC118
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 12, 2022
Lead Product(s) : Telitacicept
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
RemeGen Releases Phase II Clinical Study Data for Treatment of Myasthenia Gravis in Chinese Patients
Details : RC18 (telitacicept) targets two cell-signaling molecules critical for B-lymphocyte development: BLyS and a proliferation inducing ligand, which allows it to effectively reduce B-cell mediated autoimmune responses that are implicated in several autoimmune...
Brand Name : RC18
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 01, 2022
Lead Product(s) : Telitacicept
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Telitacicept,Interleukin 2
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Preliminary results from the full analysis set (FAS) showed that at week 52, patients who received RC-18 (telitacicept) had a significantly higher rate of SRI-4 (The Systemic Lupus Erythematosus Responder Index 4) response than those who received placebo...
Brand Name : RC-18
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 19, 2022
Lead Product(s) : Telitacicept,Interleukin 2
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Seagen Licenses Disitamab Vedotin, a Novel HER2-targeted Antibody-Drug Conjugate (ADC) from RemeGen. Disitamab vedotin is a novel ADC that selectively delivers the anti-cancer agent monomethyl auristatin E (MMAE) into HER2-expressing tumor cells.
Brand Name : RC48
Molecule Type : Large molecule
Upfront Cash : $200.0 million
August 09, 2021
Details : The approval of Disitamab vedotin has broken the situation that there is no original domestic new drug in the field of ADC drugs, and filled the gap in the global post-line treatment of patients with HER2 over-expression of gastric cancer.
Brand Name : Aidexi
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 09, 2021
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