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    [{"orgOrder":0,"company":"Renibus Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Iron Sucrose","moa":"","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase II","graph3":"Renibus Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Renibus Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Renibus Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Renibus Therapeutics","sponsor":"Frontier Scientific","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Small molecule","year":"2020","type":"Collaboration","leadProduct":"Stannous protoporphyrin","moa":"","graph1":"Infections and Infectious 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    Find Clinical Drug Pipeline Developments & Deals by Renibus Therapeutics

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                            01

                            Renibus Therapeutics

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                            Fi Europe 2024
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                            Renibus Therapeutics

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                            Lead Product(s) : Stannic Protoporfin,Iron Sucrose

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Renibus Announces Publication Of Results from Phase 2 Study Evaluating RBT-1

                            Details : RBT-1 (stannic protoporfin/iron sucrose), is a potent inducer of anti-inflammatory, antioxidant and iron-scavenging pathways, reduces post-op complications following cardiothoracic surgery.

                            Brand Name : RBT-1

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            January 09, 2024

                            Lead Product(s) : Stannic Protoporfin,Iron Sucrose

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Renibus Therapeutics

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                            Fi Europe 2024
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                            Renibus Therapeutics

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                            Lead Product(s) : Stannic Protoporfin,Iron Sucrose

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Renibus Announces First Patient Enrolled in PROTECT Phase 3 Study of RBT-1 to Reduce Post-operative Complicati...

                            Details : RBT-1 (stannic protoporfin/iron sucrose) is a potent inducer of anti-inflammatory, antioxidant and iron-scavenging pathways currently in Phase 3 [NCT # 06021457] for its lead indication to reduce post-operative complications following cardiothoracic surg...

                            Brand Name : RBT-1

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 25, 2023

                            Lead Product(s) : Stannic Protoporfin,Iron Sucrose

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Renibus Therapeutics

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                            Fi Europe 2024
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                            Renibus Therapeutics

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                            Lead Product(s) : Iron Sucrose,Stannus Protoporphyrin

                            Therapeutic Area : Nephrology

                            Study Phase : Phase II

                            Sponsor : Juniper Point

                            Deal Size : $72.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Renibus Therapeutics Announces Final Close of Upsized Series B Financing, Bringing Total Round to $72 Million

                            Details : The proceeds will advance RBT-1 through a pivotal Phase 3 trial for reducing the risk of post-operative complications following cardiothoracic surgery. RBT-1 (stannic protoporfin/iron sucrose) is a potent inducer of anti-inflammatory, antioxidant and iro...

                            Brand Name : RBT-1

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            September 12, 2023

                            Lead Product(s) : Iron Sucrose,Stannus Protoporphyrin

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase II

                            Sponsor : Juniper Point

                            Deal Size : $72.0 million

                            Deal Type : Series B Financing

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                            04

                            Renibus Therapeutics

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                            Fi Europe 2024
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                            Renibus Therapeutics

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                            Lead Product(s) : Stannic Protoporfin,Iron Sucrose

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : $47.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Renibus Therapeutics Announces $47 Million Financing to Advance Lead Program RBT-1 Through Pivotal Phase 3 Tri...

                            Details : The proceeds will advance RBT-1 (stannic protoporfin/iron sucrose), a potent inducer of anti-inflammatory, antioxidant and iron scavenging pathways, through Phase 3 trial for reducing the risk of post-operative complications following cardiothoracic surg...

                            Brand Name : RBT-1

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            July 18, 2023

                            Lead Product(s) : Stannic Protoporfin,Iron Sucrose

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : $47.0 million

                            Deal Type : Series B Financing

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                            05

                            Renibus Therapeutics

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                            Fi Europe 2024
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                            Renibus Therapeutics

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                            Lead Product(s) : Iron Sucrose,Stannus Protoporphyrin

                            Therapeutic Area : Nephrology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Renibus Therapeutics Announces Breakthrough Therapy Designation from US FDA for RBT-1 for the Reduction in Ris...

                            Details : RBT-1 (stannic protoporfin/iron sucrose) is a potent inducer of anti-inflammatory, antioxidant and iron-scavenging pathways that is advancing toward for its lead indication to reduce post-operative complications following cardiothoracic surgery.

                            Brand Name : RBT-1

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 11, 2023

                            Lead Product(s) : Iron Sucrose,Stannus Protoporphyrin

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Renibus Therapeutics

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                            Fi Europe 2024
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                            Renibus Therapeutics

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                            Lead Product(s) : Iron Sucrose,Stannus Protoporphyrin

                            Therapeutic Area : Nephrology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Renibus Therapeutics Announces Positive 30-Day Topline Data from RBT-1 Phase 2 Trial

                            Details : RBT-1 (Iron sucrose), treated patients demonstrated a highly significant increase in anti-inflammatory and antioxidant biomarkers of cytoprotective preconditioning. The biomarkers assessed were interleukin-10, heme oxygenase-1 and ferritin.

                            Brand Name : RBT-1

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            January 05, 2023

                            Lead Product(s) : Iron Sucrose,Stannus Protoporphyrin

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Renibus Therapeutics

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                            Fi Europe 2024
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                            Renibus Therapeutics

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                            Lead Product(s) : Iron Sucrose,Stannus Protoporphyrin

                            Therapeutic Area : Nephrology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Renibus Therapeutics Announces Positive Interim Data from RBT-1 Phase 2 Trial

                            Details : RBT-1 (Iron Sucrose) met primary endpoint of increasing the expression of biomarkers of cytoprotective preconditioning; positive data supports the potential for RBT-1 to impact clinical outcomes in cardiothoracic surgery patients.

                            Brand Name : RBT-1

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 15, 2022

                            Lead Product(s) : Iron Sucrose,Stannus Protoporphyrin

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Renibus Therapeutics

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                            Renibus Therapeutics

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                            Lead Product(s) : Iron Sucrose,Stannus Protoporphyrin

                            Therapeutic Area : Nephrology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : $35.0 million

                            Deal Type : Series A Financing

                            DEALS_DEV arrow-down

                            Renibus Therapeutics Announces Appointment of Frank Stonebanks as CEO and $35 Million Series A Funding

                            Details : Proceeds from the recent financing will be used to advance Renibus’ pipeline, including the company’s lead candidates, RBT-1 for prevention of acute kidney injury (AKI), currently in a large (126 patients), randomized, double-blind study in AKI in a ...

                            Brand Name : RBT-1

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            February 15, 2022

                            Lead Product(s) : Iron Sucrose,Stannus Protoporphyrin

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : $35.0 million

                            Deal Type : Series A Financing

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                            09

                            Renibus Therapeutics

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                            Fi Europe 2024
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                            Renibus Therapeutics

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                            Lead Product(s) : Iron Sucrose,Stannus Protoporphyrin

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Renibus Therapeutics Initiates Phase 2 Study of RBT-1 for Prevention of Acute Kidney Injury

                            Details : This Phase 2 study will evaluate the efficacy of RBT-1 in generating a preconditioning response as measured by a composite of biomarkers in subjects who are at risk for AKI following cardiac surgery.

                            Brand Name : RBT-1

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 11, 2021

                            Lead Product(s) : Iron Sucrose,Stannus Protoporphyrin

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Renibus Therapeutics

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                            Renibus Therapeutics

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                            Lead Product(s) : Iron Sucrose,Stannus Protoporphyrin

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Rénibus Therapeutics to Present Phase 1b Data on RBT-1 at Acute Kidney Injury & Continuous Renal Replacement ...

                            Details : Rénibus Therapeutics will present Phase 1b clinical trial data on RBT-1, its investigational treatment for the prevention of acute kidney injury (AKI), at the Acute Kidney Injury & Continuous Renal Replacement Therapy (AKI & CRRT) 2021 Conference.

                            Brand Name : RBT-1

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            February 25, 2021

                            Lead Product(s) : Iron Sucrose,Stannus Protoporphyrin

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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