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    [{"orgOrder":0,"company":"RespireRx Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"CX717","moa":"Ionotropic glutamate receptor","graph1":"Psychiatry\/Psychology","graph2":"Phase II","graph3":"RespireRx Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"RespireRx Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"RespireRx Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"RespireRx Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"KRM-II-81","moa":"GABAA 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Inapplicable"},{"orgOrder":0,"company":"RespireRx Pharmaceuticals","sponsor":"Department of Defense","pharmaFlowCategory":"D","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Funding","leadProduct":"Ampakine","moa":"Undisclosed","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase II","graph3":"RespireRx Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"RespireRx Pharmaceuticals \/ Department of Defense","highestDevelopmentStatusID":"8","companyTruncated":"RespireRx Pharmaceuticals \/ Department of Defense"},{"orgOrder":0,"company":"RespireRx Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"U.S.A","productType":"Other Small 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Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"RespireRx Pharmaceuticals \/ National Institutes on Drug Abuse","highestDevelopmentStatusID":"4","companyTruncated":"RespireRx Pharmaceuticals \/ National Institutes on Drug Abuse"}]

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                            01

                            RespireRx Pharmaceuticals

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                            AACR Annual meeting
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                            RespireRx Pharmaceuticals

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                            Lead Product(s) : Ampakine

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Phase II

                            Sponsor : Department of Defense

                            Deal Size : $1.8 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            RespireRx Pharmaceuticals Receives DOD Award for Phase 2 Study on CX1739 in Spinal Injury

                            Details : RespireRx intends to use the net proceeds to fund phase 2 clinical study of CX1739, its Lead AMPAkine, to improve bladder function in patients with spinal cord injury.

                            Product Name : CX1739

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            May 29, 2024

                            Lead Product(s) : Ampakine

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Phase II

                            Sponsor : Department of Defense

                            Deal Size : $1.8 million

                            Deal Type : Funding

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                            02

                            RespireRx Pharmaceuticals

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                            AACR Annual meeting
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                            AACR Annual meeting
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                            Lead Product(s) : KRM-II-81

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            RespireRx Reports Preclinical Pain Relief for Non-Opioid Lead GABAkine Product

                            Details : KRM-II-81 is an orally bioavailable imidazodiazepines that acts as a GABA-A receptor potentiator (GABAkine). It is being developed for the treatment of pain.

                            Product Name : KRM-II-81

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 13, 2024

                            Lead Product(s) : KRM-II-81

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            RespireRx Pharmaceuticals

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                            AACR Annual meeting
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                            RespireRx Pharmaceuticals

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                            AACR Annual meeting
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                            Lead Product(s) : Tetrahydrocannabinol

                            Therapeutic Area : Sleep

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            RespireRx Pharmaceuticals Inc. Establishes ResolutionRx Ltd in Australia to Develop Its Pharmaceutical Cannabi...

                            Details : Dronabinol, delta-9-THC, is a synthetic version of the naturally occurring substance in the cannabis plant. Drug is an endocannabinoid CB1 and CB2 receptor agonist which is being developed for the treatment of Obstructive sleep apnea.

                            Product Name : ResolutionRx

                            Product Type : Controlled Substance

                            Upfront Cash : Inapplicable

                            December 01, 2023

                            Lead Product(s) : Tetrahydrocannabinol

                            Therapeutic Area : Sleep

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            RespireRx Pharmaceuticals

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                            AACR Annual meeting
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                            RespireRx Pharmaceuticals

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                            AACR Annual meeting
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                            Lead Product(s) : Tetrahydrocannabinol

                            Therapeutic Area : Sleep

                            Study Phase : Phase II

                            Sponsor : ResolutionRx

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            RespireRx Pharmaceuticals Inc. and ResolutionRx Ltd Enter into Bilateral Agreements to Establish ResolutionRx ...

                            Details : Under the agreement, ResolutionRx will use and exploit the Licensed IP associated with new dronabinol formulations initially to be developed for the treatment of obstructive sleep apnea.

                            Product Name : ResolutionRx

                            Product Type : Controlled Substance

                            Upfront Cash : Undisclosed

                            September 08, 2023

                            Lead Product(s) : Tetrahydrocannabinol

                            Therapeutic Area : Sleep

                            Highest Development Status : Phase II

                            Sponsor : ResolutionRx

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            05

                            RespireRx Pharmaceuticals

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                            AACR Annual meeting
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                            AACR Annual meeting
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                            Lead Product(s) : Ampakine

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Preclinical

                            Sponsor : University College London

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            RespireRx Pharmaceuticals Inc. Establishes Research Collaboration With University College London to Study the ...

                            Details : The collaboration aims to to study the possibility of using CX1739, RespireRx’s lead clinical AMPAkine, for the treatment of a major class of GRIA disorders.

                            Product Name : CX1739

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            May 04, 2023

                            Lead Product(s) : Ampakine

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Preclinical

                            Sponsor : University College London

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            06

                            RespireRx Pharmaceuticals

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                            AACR Annual meeting
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                            AACR Annual meeting
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                            Lead Product(s) : KRM-II-81

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            RespireRx Pharmaceuticals Inc. Discloses Novel Structural Analogs of its GABAA Receptor Potentiator, KRM-II-81...

                            Details : KRM-II-81 analogs enhances the GABAergic neurotransmission and function as orally-bioavailable anti-seizure agents in the absence of the sedation typically associated with GABA augmentation.

                            Product Name : KRM-II-81

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 04, 2023

                            Lead Product(s) : KRM-II-81

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            RespireRx Pharmaceuticals

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                            AACR Annual meeting
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                            RespireRx Pharmaceuticals

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                            AACR Annual meeting
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                            Lead Product(s) : KRM-II-81

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            RespireRx Pharmaceuticals Inc. Discloses Novel Structural Analogs of its GABAA Receptor Potentiator, KRM-II-81...

                            Details : The compounds described in these articles were efficacious as anticonvulsants and the most characterized of these, KRM-II-81, KPP-III-34, displayed robust activity in more advanced anti-seizure models. All compounds were effective without producing sedat...

                            Product Name : KRM-II-81

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 04, 2023

                            Lead Product(s) : KRM-II-81

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            RespireRx Pharmaceuticals

                            U.S.A arrow
                            AACR Annual meeting
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                            RespireRx Pharmaceuticals

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                            Lead Product(s) : Tetrahydrocannabinol

                            Therapeutic Area : Sleep

                            Study Phase : Phase II

                            Sponsor : University Of Illinois Chicago

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            RespireRx Pharmaceuticals Inc. Announces the 2nd Amendment to its License Agreement with the University of Ill...

                            Details : D9-THC (dronabinol, D9-tetrahydrocannabinol) is an oral capsule drug product that is being tested for clinical efficacy in patients with obstructive sleep apnea (OSA).

                            Product Name : ResolutionRx

                            Product Type : Controlled Substance

                            Upfront Cash : Undisclosed

                            January 23, 2023

                            Lead Product(s) : Tetrahydrocannabinol

                            Therapeutic Area : Sleep

                            Highest Development Status : Phase II

                            Sponsor : University Of Illinois Chicago

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            09

                            RespireRx Pharmaceuticals

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                            AACR Annual meeting
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                            RespireRx Pharmaceuticals

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                            AACR Annual meeting
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                            Lead Product(s) : Tetrahydrocannabinol

                            Therapeutic Area : Sleep

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            RespireRx Pharmaceuticals Inc. Announces that Sleep Review has discussed the RespireRx Dronabinol Obstructive ...

                            Details : RespireRx’s ResolutionRx business unit is developing dronabinol, ∆-9-THC, a synthetic version of the naturally occurring substance in the cannabis plant, for the treatment of OSA.

                            Product Name : ResolutionRx

                            Product Type : Controlled Substance

                            Upfront Cash : Inapplicable

                            August 08, 2022

                            Lead Product(s) : Tetrahydrocannabinol

                            Therapeutic Area : Sleep

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            RespireRx Pharmaceuticals

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                            AACR Annual meeting
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                            Lead Product(s) : CX717

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            RespireRx Pharmaceuticals Inc. Announces Recent RespireRx Presentation at 2022 GRI Virtual Conference presente...

                            Details : After having shown positive activity in animal models of ADHD, CX717, lead AMPAkines, demonstrated statistically significant improvement of symptoms observed in a Phase 2 human clinical trial in adult patients with ADHD.

                            Product Name : CX717

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 17, 2022

                            Lead Product(s) : CX717

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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