Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Dactolisib
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Recipient : TrialSpark
Deal Size : Undisclosed
Deal Type : Collaboration
Details : TrialSpark's integrated tech platform and trial model will enable resTORbio to accelerate their clinical trials of RTB-101 for COVID-19 in community/outpatient settings.
Brand Name : RTB-101
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 28, 2020
Lead Product(s) : Dactolisib
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Recipient : TrialSpark
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Dactolisib
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : National Institute on Aging
Deal Size : Undisclosed
Deal Type : Funding
Details : Funding to support a randomized, double-blind, placebo-controlled pilot study of RTB101 as compared to placebo for COVID-19 post-exposure prophylaxis in older adults.
Brand Name : RTB101
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 28, 2020
Lead Product(s) : Dactolisib
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : National Institute on Aging
Deal Size : Undisclosed
Deal Type : Funding
Lead Product(s) : Dactolisib
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The study is supported by additional data observed in resTORbio Phase 2b and Phase 3 clinical trials which suggest the potential of RTB101 to reduce the severity of laboratory-confirmed coronavirus infections.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 28, 2020
Lead Product(s) : Dactolisib
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ADI-001
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Adicet Bio
Deal Size : Undisclosed
Deal Type : Merger
Details : Merger aimed at providing resources for the combined company to advance multiple programs into the clinic, including Adicet’s lead candidate, ADI-001, a gamma delta CAR-T cell therapy targeting CD20.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
April 29, 2020
Lead Product(s) : ADI-001
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Adicet Bio
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : Dactolisib
Therapeutic Area : Neurology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
resTORbio Announces Delay of its Ongoing Phase 1b/2a trial of RTB101
Details : Company will postpone enrollment in the fifth cohort of its ongoing Phase 1b/2a trial of RTB101 alone or in combination with sirolimus, in Parkinson’s disease (PD).
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 03, 2020
Lead Product(s) : Dactolisib
Therapeutic Area : Neurology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Dactolisib
Therapeutic Area : Neurology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Interim data from three cohorts in the Phase 1b/2a study demonstrate that RTB101 is well tolerated, effective in preclinical models to inhibit the activity of TORC1 and induce autophagy.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 19, 2020
Lead Product(s) : Dactolisib
Therapeutic Area : Neurology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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