Lead Product(s) : MRT-8102
Therapeutic Area : Rheumatology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Monte Rosa Begins IND Studies for MRT-8102, a NEK7 Directed Degrader
Details : MRT-8102 is a first-in-class NEK7-directed molecular glue degrader and NLRP3/IL-1β pathway inhibitor being evaluated for multiple inflammatory diseases, including gout and pericarditis.
Product Name : MRT-8102
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 03, 2024
Lead Product(s) : MRT-8102
Therapeutic Area : Rheumatology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Colchicine,Ropivacaine Hydrochloride
Therapeutic Area : Rheumatology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
PK MED Gets FDA Clearance to Initiate Clinical Program for PKM-01 in Gout Flares
Details : PKM-01 (colchicine) is an intra-articular combination of a fast-acting anesthetic and a controlled-release form of a powerful anti-inflammatory agent (colchicine). Being evaluated for gout flares.
Product Name : PKM-01
Product Type : Plant Extract/Herbal
Upfront Cash : Inapplicable
February 26, 2024
Lead Product(s) : Colchicine,Ropivacaine Hydrochloride
Therapeutic Area : Rheumatology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ABP-745
Therapeutic Area : Rheumatology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Atom Bioscience Receives FDA IND Clearance for Clinical Trial of ABP-745 for Acute Gout
Details : ABP-745 is an oral small molecule for treating acute gout, showing significant safety improvement and reducing inflammatory factors in preclinical trials compared to similar drugs.
Product Name : ABP-745
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 01, 2024
Lead Product(s) : ABP-745
Therapeutic Area : Rheumatology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : SYNB2081
Therapeutic Area : Rheumatology
Study Phase : IND Enabling
Sponsor : Ginkgo Bioworks
Deal Size : Inapplicable
Deal Type : Inapplicable
Synlogic Announces Synthetic Biotic for Gout Developed in Partnership with Ginkgo Bioworks
Details : The new candidate, SYNB2081, is a Synthetic Biotic and is the second product to advance to clinical development through a research collaboration between Synlogic and Ginkgo, following investigational new drug candidate SYNB1353 for the potential treatmen...
Product Name : SYNB2081
Product Type : Probiotic
Upfront Cash : Inapplicable
November 08, 2022
Lead Product(s) : SYNB2081
Therapeutic Area : Rheumatology
Highest Development Status : IND Enabling
Sponsor : Ginkgo Bioworks
Deal Size : Inapplicable
Deal Type : Inapplicable