Lead Product(s) : MRT-8102
Therapeutic Area : Rheumatology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Monte Rosa Begins IND Studies for MRT-8102, a NEK7 Directed Degrader
Details : MRT-8102 is a first-in-class NEK7-directed molecular glue degrader and NLRP3/IL-1β pathway inhibitor being evaluated for multiple inflammatory diseases, including gout and pericarditis.
Brand Name : MRT-8102
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 11, 2024
Lead Product(s) : MRT-8102
Therapeutic Area : Rheumatology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Colchicine,Ropivacaine Hydrochloride
Therapeutic Area : Rheumatology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
PK MED Gets FDA Clearance to Initiate Clinical Program for PKM-01 in Gout Flares
Details : PKM-01 (colchicine) is an intra-articular combination of a fast-acting anesthetic and a controlled-release form of a powerful anti-inflammatory agent (colchicine). Being evaluated for gout flares.
Brand Name : PKM-01
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 26, 2024
Lead Product(s) : Colchicine,Ropivacaine Hydrochloride
Therapeutic Area : Rheumatology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ABP-745
Therapeutic Area : Rheumatology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Atom Bioscience Receives FDA IND Clearance for Clinical Trial of ABP-745 for Acute Gout
Details : ABP-745 is an oral small molecule for treating acute gout, showing significant safety improvement and reducing inflammatory factors in preclinical trials compared to similar drugs.
Brand Name : ABP-745
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 02, 2024
Lead Product(s) : ABP-745
Therapeutic Area : Rheumatology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : SYNB2081
Therapeutic Area : Rheumatology
Study Phase : IND Enabling
Sponsor : Ginkgo Bioworks
Deal Size : Not Applicable
Deal Type : Not Applicable
Synlogic Announces Synthetic Biotic for Gout Developed in Partnership with Ginkgo Bioworks
Details : The new candidate, SYNB2081, is a Synthetic Biotic and is the second product to advance to clinical development through a research collaboration between Synlogic and Ginkgo, following investigational new drug candidate SYNB1353 for the potential treatmen...
Brand Name : SYNB2081
Molecule Type : Large molecule
Upfront Cash : Not Applicable
August 11, 2022
Lead Product(s) : SYNB2081
Therapeutic Area : Rheumatology
Highest Development Status : IND Enabling
Sponsor : Ginkgo Bioworks
Deal Size : Not Applicable
Deal Type : Not Applicable
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