[{"orgOrder":0,"company":"Jiangsu Atom Bioscience & Pharmaceutical","sponsor":"Xicheng Jinrui Equity Investment Fund","pharmaFlowCategory":"D","therapeuticArea":"Rheumatology","country":"CHINA","productType":"Other Small Molecule","year":"2022","type":"Series C Financing","leadProduct":"Lingdolinurad","moa":"Urate transporter protein","graph1":"Rheumatology","graph2":"Phase II","graph3":"Jiangsu Atom Bioscience & Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Jiangsu Atom Bioscience & Pharmaceutical \/ Xicheng Jinrui Equity Investment Fund","highestDevelopmentStatusID":"8","companyTruncated":"Jiangsu Atom Bioscience & Pharmaceutical \/ Xicheng Jinrui Equity Investment Fund"},{"orgOrder":0,"company":"Arthrosi Therapeutics","sponsor":"Guangrun Health Industry","pharmaFlowCategory":"D","therapeuticArea":"Rheumatology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Series D Financing","leadProduct":"AR882","moa":"URAT1","graph1":"Rheumatology","graph2":"Phase II","graph3":"Arthrosi Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Oral Capsule, Immediate Release","sponsorNew":"Arthrosi Therapeutics \/ Guangrun Health Industry","highestDevelopmentStatusID":"8","companyTruncated":"Arthrosi Therapeutics \/ Guangrun Health Industry"},{"orgOrder":0,"company":"Allena Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"U.S.A","productType":"Enzyme","year":"2021","type":"Inapplicable","leadProduct":"Engineered Urate Oxidase","moa":"Urate","graph1":"Rheumatology","graph2":"Phase II","graph3":"Allena Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Allena Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Allena Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Allena Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"U.S.A","productType":"Enzyme","year":"2021","type":"Inapplicable","leadProduct":"Engineered Urate Oxidase","moa":"Urate","graph1":"Rheumatology","graph2":"Phase II","graph3":"Allena Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Allena Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Allena Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Dyve Biosciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"DYV700","moa":"Undisclosed","graph1":"Rheumatology","graph2":"Phase II","graph3":"Dyve Biosciences","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Topical Lotion","sponsorNew":"Dyve Biosciences \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Dyve Biosciences \/ Inapplicable"},{"orgOrder":0,"company":"Dyve Biosciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Colchicine","moa":"||pH","graph1":"Rheumatology","graph2":"Phase II","graph3":"Dyve Biosciences","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Transdermal Cream","sponsorNew":"Dyve Biosciences \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Dyve Biosciences \/ Inapplicable"}]

Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                          Top Deals by Deal Size (USD bn)

                          01

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : The company intends to use the net proceeds to fund the development of AR882, a highly potent and selective next-gen URAT1 inhibitor delivered in a once daily immediate release oral capsule, being developed for the treatment of gout.

                          Product Name : AR882

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          December 07, 2023

                          Lead Product(s) : AR882

                          Therapeutic Area : Rheumatology

                          Highest Development Status : Phase II

                          Sponsor : Guangrun Health Industry

                          Deal Size : $75.0 million

                          Deal Type : Series D Financing

                          blank

                          02

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details :

                          Product Name : ABP-671

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          January 03, 2023

                          Lead Product(s) : Lingdolinurad

                          Therapeutic Area : Rheumatology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details :

                          Product Name : ABP-671

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 11, 2022

                          Lead Product(s) : Lingdolinurad

                          Therapeutic Area : Rheumatology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details :

                          Product Name : ABP-671

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          May 01, 2022

                          Lead Product(s) : Lingdolinurad

                          Therapeutic Area : Rheumatology

                          Highest Development Status : Phase II

                          Sponsor : Xicheng Jinrui Equity Investment Fund

                          Deal Size : $45.0 million

                          Deal Type : Series C Financing

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                          05

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details :

                          Product Name : ABP-671

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 21, 2022

                          Lead Product(s) : Lingdolinurad

                          Therapeutic Area : Rheumatology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : Results from US Phase 2 clinical trial—primary end point set at a challenging level confirmed the potential of LC350189 (tigulixostat) as a new gout treatment distinguished from pre-existing drugs, while also demonstrating safety similar to that of the...

                          Product Name : LC350189

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 08, 2022

                          Lead Product(s) : Tigulixostat

                          Therapeutic Area : Rheumatology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : Topical application of DYV702 significantly reduced pain intensity and duration of acute gout flare with higher overall response rates, faster time to resolution, improvements in physical function and reduction in rescue medication use.

                          Product Name : DYV702

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          January 06, 2022

                          Lead Product(s) : DYV702,Colchicine

                          Therapeutic Area : Rheumatology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : Allena recently completed a Phase 1b multiple ascending dose study of ALLN-346. The study included 18 healthy volunteers, who received either ALLN-346 or placebo (2:1 randomization) for seven days.

                          Product Name : ALLN-346

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          September 29, 2021

                          Lead Product(s) : Engineered Urate Oxidase

                          Therapeutic Area : Rheumatology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : Company is developing ALLN-346 for the treatment of hyperuricemia and gout in the setting of advanced CKD, with a Phase 1 multiple ascending dose study recently completed and a Phase 2a program underway.

                          Product Name : ALLN-346

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          March 11, 2021

                          Lead Product(s) : Engineered Urate Oxidase

                          Therapeutic Area : Rheumatology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : This strategic licensing agreement is for SEL-212, a combination of Selecta's tolerogenic ImmTOR immune tolerance platform and a therapeutic uricase enzyme (pegadricase) for the treatment of chronic refractory gout.

                          Product Name : SEL-212

                          Product Type : Enzyme

                          Upfront Cash : Undisclosed

                          November 06, 2020

                          Lead Product(s) : Pegadricase

                          Therapeutic Area : Rheumatology

                          Highest Development Status : Phase II

                          Sponsor : Swedish Orphan Biovitrum AB

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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