Lead Product(s) : AR882
Therapeutic Area : Rheumatology
Study Phase : Phase II
Sponsor : Guangrun Health Industry
Deal Size : $75.0 million
Deal Type : Series D Financing
Arthrosi Secures $75M in Series D Financing
Details : The company intends to use the net proceeds to fund the development of AR882, a highly potent and selective next-gen URAT1 inhibitor delivered in a once daily immediate release oral capsule, being developed for the treatment of gout.
Product Name : AR882
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
December 07, 2023
Lead Product(s) : AR882
Therapeutic Area : Rheumatology
Highest Development Status : Phase II
Sponsor : Guangrun Health Industry
Deal Size : $75.0 million
Deal Type : Series D Financing
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details :
Product Name : ABP-671
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 03, 2023
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details :
Product Name : ABP-671
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 11, 2022
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Study Phase : Phase II
Sponsor : Xicheng Jinrui Equity Investment Fund
Deal Size : $45.0 million
Deal Type : Series C Financing
Details :
Product Name : ABP-671
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
May 01, 2022
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Highest Development Status : Phase II
Sponsor : Xicheng Jinrui Equity Investment Fund
Deal Size : $45.0 million
Deal Type : Series C Financing
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details :
Product Name : ABP-671
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 21, 2022
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tigulixostat
Therapeutic Area : Rheumatology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
LG Chem Enters Final Stage of Clinical Development for New Gout Drug
Details : Results from US Phase 2 clinical trial—primary end point set at a challenging level confirmed the potential of LC350189 (tigulixostat) as a new gout treatment distinguished from pre-existing drugs, while also demonstrating safety similar to that of the...
Product Name : LC350189
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 08, 2022
Lead Product(s) : Tigulixostat
Therapeutic Area : Rheumatology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : DYV702,Colchicine
Therapeutic Area : Rheumatology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Topical application of DYV702 significantly reduced pain intensity and duration of acute gout flare with higher overall response rates, faster time to resolution, improvements in physical function and reduction in rescue medication use.
Product Name : DYV702
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 06, 2022
Lead Product(s) : DYV702,Colchicine
Therapeutic Area : Rheumatology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Engineered Urate Oxidase
Therapeutic Area : Rheumatology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Allena Pharmaceuticals Commences Dosing of Gout Patients in Second Phase 2a Trial of ALLN-346
Details : Allena recently completed a Phase 1b multiple ascending dose study of ALLN-346. The study included 18 healthy volunteers, who received either ALLN-346 or placebo (2:1 randomization) for seven days.
Product Name : ALLN-346
Product Type : Enzyme
Upfront Cash : Inapplicable
September 29, 2021
Lead Product(s) : Engineered Urate Oxidase
Therapeutic Area : Rheumatology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Engineered Urate Oxidase
Therapeutic Area : Rheumatology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Company is developing ALLN-346 for the treatment of hyperuricemia and gout in the setting of advanced CKD, with a Phase 1 multiple ascending dose study recently completed and a Phase 2a program underway.
Product Name : ALLN-346
Product Type : Enzyme
Upfront Cash : Inapplicable
March 11, 2021
Lead Product(s) : Engineered Urate Oxidase
Therapeutic Area : Rheumatology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pegadricase
Therapeutic Area : Rheumatology
Study Phase : Phase II
Sponsor : Swedish Orphan Biovitrum AB
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : This strategic licensing agreement is for SEL-212, a combination of Selecta's tolerogenic ImmTOR immune tolerance platform and a therapeutic uricase enzyme (pegadricase) for the treatment of chronic refractory gout.
Product Name : SEL-212
Product Type : Enzyme
Upfront Cash : Undisclosed
November 06, 2020
Lead Product(s) : Pegadricase
Therapeutic Area : Rheumatology
Highest Development Status : Phase II
Sponsor : Swedish Orphan Biovitrum AB
Deal Size : Undisclosed
Deal Type : Licensing Agreement