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Find Clinical Drug Pipeline Developments & Deals by Rhythm Pharmaceuticals

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01

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Through the termination, Rhythm will reacquires the rights of Imcivree (setmelanotide acetate). It is being indicated for the treatment of obesity.

Product Name : Imcivree

Product Type : Peptide

Upfront Cash : $6.3 million

March 20, 2025

Lead Product(s) : Setmelanotide Acetate

Therapeutic Area : Nutrition and Weight Loss

Highest Development Status : Approved FDF

Recipient : RareStone Group

Deal Size : $6.3 million

Deal Type : Termination

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02

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Imcivree (setmelanotide) is a subcutaneously administered, MC4 R agonist. It is being investigated for the treatment of acquired hypothalamic obesity.

Product Name : Imcivree

Product Type : Peptide

Upfront Cash : Inapplicable

March 19, 2025

Lead Product(s) : Setmelanotide Acetate

Therapeutic Area : Nutrition and Weight Loss

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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03

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Imcivree (setmelanotide) is a MC4 R agonist. It is the approved weight management treatment in pediatric patients (2-6 years) with obesity due to Bardet-Biedl syndrome.

Product Name : Undisclosed

Product Type : Peptide

Upfront Cash : Not Applicable

December 20, 2024

Lead Product(s) : Setmelanotide Acetate

Therapeutic Area : Genetic Disease

Highest Development Status : Approved

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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04

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Imcivree (setmelanotide) is a MC4 R agonist. It is the approved weight management treatment in pediatric patients (2-6 years) with obesity due to Bardet-Biedl syndrome.

Product Name : Undisclosed

Product Type : Peptide

Upfront Cash : Not Applicable

December 03, 2024

Lead Product(s) : Setmelanotide Acetate

Therapeutic Area : Genetic Disease

Highest Development Status : Approved

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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05

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : The collaboration aims to advanced the clinical development of AXV-101, which is being evaluated in the early-stage clinical trial studies for the treatment of Bardet-Biedl syndrome.

Product Name : AXV-101

Product Type : Cell and Gene therapy

Upfront Cash : Undisclosed

October 24, 2024

Lead Product(s) : AXV-101

Therapeutic Area : Genetic Disease

Highest Development Status : Preclinical

Sponsor : Axovia Therapeutics

Deal Size : Undisclosed

Deal Type : Collaboration

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06

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Imcivree (setmelanotide) is a MC4 R agonist. It is the approved weight management treatment in pediatric patients (2-6 years) with obesity due to Bardet-Biedl syndrome.

Product Name : Imcivree

Product Type : Peptide

Upfront Cash : Not Applicable

August 26, 2024

Lead Product(s) : Setmelanotide Acetate

Therapeutic Area : Genetic Disease

Highest Development Status : Phase III

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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07

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Imcivree (setmelanotide) is a MC4 R agonist. It is the approved weight management treatment in pediatric patients (2-6 years) with obesity due to Bardet-Biedl syndrome.

Product Name : Imcivree

Product Type : Peptide

Upfront Cash : Not Applicable

July 31, 2024

Lead Product(s) : Setmelanotide Acetate

Therapeutic Area : Genetic Disease

Highest Development Status : Approved

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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08

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : LB54640 is an investigational oral melanocortin-4 receptor agonist, and the first patients have been dosed in the Company’s Phase 2 clinical trial to treat hypothalamic obesity.

Product Name : LB54640

Product Type : Small molecule

Upfront Cash : Not Applicable

July 23, 2024

Lead Product(s) : LB54640

Therapeutic Area : Nutrition and Weight Loss

Highest Development Status : Phase II

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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09

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Imcivree (setmelanotide) is a MC4 R agonist. It is the 1st & only therapy approved in Canada for weight management in adult & pediatric patients (≥6 years) with obesity due to Bardet-Biedl syndrome.

Product Name : Imcivree

Product Type : Peptide

Upfront Cash : Not Applicable

June 28, 2024

Lead Product(s) : Setmelanotide Acetate

Therapeutic Area : Genetic Disease

Highest Development Status : Approved

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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10

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Imcivree (setmelanotide) is a MC4 R agonist. It is the 1st & only therapy approved in Canada for weight management in adult & pediatric patients (≥6 years) with obesity due to Bardet-Biedl syndrome.

Product Name : Imcivree

Product Type : Peptide

Upfront Cash : Not Applicable

May 22, 2024

Lead Product(s) : Setmelanotide Acetate

Therapeutic Area : Genetic Disease

Highest Development Status : Approved

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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