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Find Clinical Drug Pipeline Developments & Deals for RLY-4008

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : The net proceeds from the offering will be used for research & development of the Company’s lead product, including RLY-4008 for the treatment of FGFR2-mutated Cholangiocarcinoma and other neoplasms.

                          Brand Name : RLY-4008

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          September 10, 2024

                          Lead Product(s) : RLY-4008

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Goldman Sachs & Co

                          Deal Size : $200.0 million

                          Deal Type : Public Offering

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                          02

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : The net proceeds from the offering will be used for research & development of the Company’s lead product, including RLY-4008 for the treatment of FGFR2-mutated Cholangiocarcinoma and other neoplasms.

                          Brand Name : RLY-4008

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          September 09, 2024

                          Lead Product(s) : RLY-4008

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Goldman Sachs & Co

                          Deal Size : $200.0 million

                          Deal Type : Public Offering

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                          03

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : RLY-4008 (lirafugratinib) is a potent, selective and oral small molecule inhibitor of FGFR2, a receptor tyrosine kinase that is frequently altered in certain cancers and demonstrated FGFR2-dependent killing in cancer cell lines and induced regression in ...

                          Brand Name : RLY-4008

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 12, 2023

                          Lead Product(s) : RLY-4008

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : RLY-4008 is a potent, selective and oral small molecule inhibitor of FGFR2, a receptor tyrosine kinase that is frequently altered in certain cancers and demonstrated FGFR2-dependent killing in cancer cell lines and induced regression in in vivo models.

                          Brand Name : RLY-4008

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          May 25, 2023

                          Lead Product(s) : RLY-4008

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : RLY-4008 demonstrated 88% overall response rate (15 out of 17) from interim data of pan-FGFR treatment (FGFRi)-naïve FGFR2-fusion cholangiocarcinoma (CCA) patients treated at the pivotal dose.

                          Brand Name : RLY-4008

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 11, 2022

                          Lead Product(s) : RLY-4008

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : RLY-4008 is a potent, selective and oral small molecule inhibitor of FGFR2, a receptor tyrosine kinase that is frequently altered in certain cancers,demonstrated FGFR2-dependent killing in cancer cell lines and induced regression in vivo models.

                          Brand Name : RLY-4008

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          August 18, 2022

                          Lead Product(s) : RLY-4008

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : First patient has been dosed in a first-in-human clinical trial of RLY-4008 enriched for patients with intrahepatic cholangiocarcinoma and other advanced solid tumors harboring a fibroblast growth factor receptor 2 alteration.

                          Brand Name : RLY-4008

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 03, 2020

                          Lead Product(s) : RLY-4008

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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