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    [{"orgOrder":0,"company":"Mitsubishi Tanabe Pharma","sponsor":"Bain Capital","pharmaFlowCategory":"D","therapeuticArea":"Psychiatry\/Psychology","country":"JAPAN","productType":"Other Small Molecule","year":"2025","type":"Acquisition","leadProduct":"Roluperidone","moa":"5-HT2A receptor","graph1":"Psychiatry\/Psychology","graph2":"Phase III","graph3":"Mitsubishi Tanabe Pharma","amount2":3.2999999999999998,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Psychiatry","amount2New":3.2999999999999998,"dosageForm":"Oral Tablet, Modified Release","sponsorNew":"Mitsubishi Tanabe Pharma \/ Bain Capital","highestDevelopmentStatusID":"10","companyTruncated":"Mitsubishi Tanabe Pharma \/ Bain Capital"},{"orgOrder":0,"company":"Minerva Neurosciences","sponsor":"Boehringer Ingelheim GmbH","pharmaFlowCategory":"D","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Private 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    01

    Mitsubishi Tanabe Pharma

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    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Study Phase : Phase III

    Sponsor : Bain Capital

    Deal Size : $3,300.0 million

    Deal Type : Acquisition

    DEALS_DEV arrow-down

    Bain Capital to Acquire Mitsubishi Tanabe Pharma Corporation

    Details : Tanabe Pharma will continue to build on its legacy of medical innovation in internal product development including MT-210 (roluperidone), being developed for schizophrenia.

    Product Name : MT-210

    Product Type : Other Small Molecule

    Upfront Cash : Undisclosed

    February 07, 2025

    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Highest Development Status : Phase III

    Sponsor : Bain Capital

    Deal Size : $3,300.0 million

    Deal Type : Acquisition

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    02

    Minerva Neurosciences

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    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Study Phase : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Minerva Receives Complete Response Letter from FDA for Roluperidone NDA

    Details : MIN-101 (roluperidone) blocks serotonin, sigma, and α-adrenergic receptors, involved in brain function regulation, and is being evaluated for treating negative symptoms in schizophrenia patients.

    Product Name : MIN-101

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    February 27, 2024

    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Highest Development Status : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Minerva Neurosciences

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    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Study Phase : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Minerva Neurosciences Announces Update on its New Drug Application (NDA) for Roluperidone for the Treatment of...

    Details : MIN-101 (roluperidone) is an investigational drug that has been shown to block serotonin, sigma and α-adrenergic receptors that are all involved in the regulation of important brain functions, including mood, cognition, sleep, and anxiety.

    Product Name : MIN-101

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    November 05, 2023

    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Highest Development Status : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Minerva Neurosciences

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    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Study Phase : Phase III

    Sponsor : Boehringer Ingelheim GmbH

    Deal Size : $20.0 million

    Deal Type : Private Placement

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    Minerva Neurosciences Announces $20 Million in Private Placement Priced at a Premium to Market

    Details : Minerva intends to use the net proceeds to support potential regulatory approval in the U.S., commercialization activities and market launch of MIN-101 (roluperidone), which is being developed for the treatment of negative symptoms in schizophrenia.

    Product Name : MIN-101

    Product Type : Other Small Molecule

    Upfront Cash : Undisclosed

    June 28, 2023

    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Highest Development Status : Phase III

    Sponsor : Boehringer Ingelheim GmbH

    Deal Size : $20.0 million

    Deal Type : Private Placement

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    Minerva Neurosciences

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    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Study Phase : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Minerva Neurosciences Announces the NDA Filing for Roluperidone for the Treatment of Negative Symptoms in Schi...

    Details : MIN-101 (roluperidone) is a compound that has been shown to block serotonin, sigma and α-adrenergic receptors that are involved in the regulation of mood, cognition, sleep and anxiety. It is being developed to treat the negative symptoms of patients wit...

    Product Name : MIN-101

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    January 05, 2023

    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Highest Development Status : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Minerva Neurosciences

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    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Study Phase : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Minerva Neurosciences Receives Refusal to File Letter from FDA for its New Drug Application for Roluperidone f...

    Details : Roluperidone (MIN-101) has been designed to block a specific subtype of serotonin receptor called 5-HT2A. When 5-HT2A is blocked, certain symptoms of schizophrenia, such as hallucinations, delusions, agitation and thought and movement disorders.

    Product Name : MIN-101

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    October 17, 2022

    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Highest Development Status : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Minerva Neurosciences

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    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Study Phase : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Minerva Neurosciences Submits New Drug Application to FDA for Roluperidone for the Treatment of Negative Sympt...

    Details : The MIN-101 (roluperidone) clinical development program aims to provide effective treatment for negative symptoms of schizophrenia, a significant unmet medical need in a large patient population.

    Product Name : MIN-101

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    August 22, 2022

    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Highest Development Status : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Minerva Neurosciences

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    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Study Phase : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Minerva Neurosciences Provides Update from Type C Meeting with FDA and Next Steps in Preparation for Submissio...

    Details : MIN-101 (roluperidone) is a compound that has been shown to block serotonin, sigma and α-adrenergic receptors that are involved in the regulation of mood, cognition, sleep and anxiety to treat negative symptoms of patients with schizophrenia.

    Product Name : MIN-101

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    July 04, 2022

    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Highest Development Status : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Minerva Neurosciences

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    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Study Phase : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Minerva Neurosciences Announces the Results of the Phase 3 Trial of Roluperidone for the Treatment of Negative...

    Details : Roluperidone at both doses was safe and well tolerated, and treatment-emergent adverse events (TEAE) were generally mild to moderate in severity.

    Product Name : MIN-101

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    November 05, 2021

    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Highest Development Status : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Minerva Neurosciences

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    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Study Phase : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Minerva Neurosciences Announces Results From Phase 3 Trial of Roluperidone (MIN-101) for Treatment of Negative...

    Details : The 64 mg and 32 mg doses were not statistically significantly different from placebo at Week 12 on the primary endpoint, the PANSS Marder Negative Symptoms Factor Score, or the key secondary endpoint, the Personal and Social Performance Scale Total Scor...

    Product Name : MIN-101

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    May 29, 2020

    Lead Product(s) : Roluperidone

    Therapeutic Area : Psychiatry/Psychology

    Highest Development Status : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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