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    [{"orgOrder":0,"company":"Shuttle Pharmaceuticals","sponsor":"Boustead Securities","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2022","type":"Public Offering","leadProduct":"Ropidoxuridine","moa":"DNA synthesis","graph1":"Oncology","graph2":"Phase I","graph3":"Shuttle Pharmaceuticals","amount2":0.01,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0.01,"dosageForm":"","sponsorNew":"Shuttle Pharmaceuticals \/ Boustead Securities","highestDevelopmentStatusID":"6","companyTruncated":"Shuttle Pharmaceuticals \/ Boustead Securities"},{"orgOrder":0,"company":"Shuttle Pharmaceuticals","sponsor":"Boustead Securities","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2022","type":"Public Offering","leadProduct":"Ropidoxuridine","moa":"DNA synthesis","graph1":"Oncology","graph2":"Phase I","graph3":"Shuttle 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Applicable","highestDevelopmentStatusID":"14","companyTruncated":"Shuttle Pharmaceuticals \/ Not Applicable"}]

    Find Clinical Drug Pipeline Developments & Deals for Ropidoxuridine

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                            01

                            Shuttle Pharmaceuticals

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                            Lead Product(s) : Ropidoxuridine

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Shuttle Pharma Expands Clinical Trial Sites for Ropidoxuridine in Glioblastoma

                            Details : IPdR (ropidoxuridine) is a radiation sensitizing agent given during radiotherapy. It is currently being investigated for the treatment of IDH-wildtype glioblastoma.

                            Brand Name : IPdR Prodrug

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 16, 2024

                            Lead Product(s) : Ropidoxuridine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Shuttle Pharmaceuticals

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                            Lead Product(s) : Ropidoxuridine

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Shuttle Pharma to Enroll Patients in Phase 2 Trial of Ropidoxuridine for Glioblastoma

                            Details : IPdR (ropidoxuridine) is a radiation sensitizing agent given during radiotherapy. It is currently being investigated for the treatment of IDH-wildtype glioblastoma.

                            Brand Name : IPdR Prodrug

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            August 14, 2024

                            Lead Product(s) : Ropidoxuridine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Shuttle Pharmaceuticals

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                            Lead Product(s) : Ropidoxuridine

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Shuttle Gets FDA Approval for Phase II Trial of Ropidoxuridine in Glioblastoma

                            Details : IPdR (ropidoxuridine) is a radiation sensitizing agent given during radiotherapy. It iscurrently being investigated for the treatment of IDH-wildtype glioblastoma.

                            Brand Name : IPdR

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            January 08, 2024

                            Lead Product(s) : Ropidoxuridine

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Shuttle Pharmaceuticals

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                            Lead Product(s) : Ropidoxuridine

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Shuttle Pharmaceuticals Submits IND Application to the U.S. FDA for Ropidoxuridine Phase II Clinical Trial for...

                            Details : IPdR Prodrug (ropidoxuridine) is a radiation sensitizing agent given during radiotherapy. It iscurrently being investigated for the treatment of IDH-wildtype glioblastoma.

                            Brand Name : IPdR Prodrug

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 11, 2023

                            Lead Product(s) : Ropidoxuridine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Shuttle Pharmaceuticals

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                            Lead Product(s) : Ropidoxuridine

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Shuttle Pharma Announces Results of Pre-IND Meeting with FDA for Ropidoxuridine Phase II Clinical Trial for Pa...

                            Details : Ropidoxuridine is a novel, orally available, thymidine analogue and prodrug for IUdR, which demonstrated a survival advantage in Phase II studies in Glioblastoma, a type of brain tumor.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 25, 2023

                            Lead Product(s) : Ropidoxuridine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Shuttle Pharmaceuticals

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                            Lead Product(s) : Ropidoxuridine

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Shuttle Pharmaceuticals Completes Manufacturing of Active Pharmaceutical Ingredient (API) for Use in Clinical ...

                            Details : Ropidoxuridine is a novel, orally available, thymidine analogue and prodrug for IUdR, which demonstrated a survival advantage in Phase II studies in anaplastic astrocytoma, a type of brain tumor.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            August 03, 2023

                            Lead Product(s) : Ropidoxuridine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Shuttle Pharmaceuticals

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                            Lead Product(s) : Ropidoxuridine

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : University of Iowa Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Shuttle Pharmaceuticals Engages UI Pharmaceuticals for Formulation and Clinical Batch Manufacture of Ropidoxur...

                            Details : The agreement aims at the formulation development and clinical batch manufacture of drug capsules of Ropidoxuridine. Ropidoxuridine is used to sensitize rapidly growing cancer cells and selective histone deacetylase inhibitors to sensitize cancer cells.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            March 09, 2023

                            Lead Product(s) : Ropidoxuridine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : University of Iowa Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            08

                            Shuttle Pharmaceuticals

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                            Lead Product(s) : Ropidoxuridine,Radiation Therapy

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Theradex Oncology

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Shuttle Pharmaceuticals Engages Theradex Oncology in Preparation for Clinical Study

                            Details : IPdR (ropidoxuridine), Shuttle's lead clinical stage product candidate, is an orally available halogenated pyrimidine (5-iodo-2-pyrimidinone-2-deoxyribose) with strong cancer radiation sensitizing properties.

                            Brand Name : IPdR

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 03, 2022

                            Lead Product(s) : Ropidoxuridine,Radiation Therapy

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Theradex Oncology

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Shuttle Pharmaceuticals

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                            Lead Product(s) : Ropidoxuridine

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : TCG GreenChem

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Shuttle Pharmaceuticals Enters into Manufacturing Agreement for Ropidoxuridine

                            Details : Ropidoxuridine (also called IPdR), the lead clinical sensitizer drug candidate, sensitizes rapidly growing cancer cells and selective histone deacetylase (HDAC) inhibitors, to sensitize cancer cells and stimulate the immune system.

                            Brand Name : IPdR

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            September 20, 2022

                            Lead Product(s) : Ropidoxuridine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : TCG GreenChem

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            10

                            Shuttle Pharmaceuticals

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                            Lead Product(s) : Ropidoxuridine

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Boustead Securities

                            Deal Size : $9.9 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Shuttle Pharmaceuticals Announces Closing of Initial Public Offering

                            Details : The net proceeds from this offering will fund Phase II clinical trials and IND-enabling studies of candidates, including radiation sensitizer Ropidoxuridine (IPdR) and the HDAC inhibitor small molecule technology platform, and working capital and general...

                            Brand Name : IPdR

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            September 06, 2022

                            Lead Product(s) : Ropidoxuridine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Boustead Securities

                            Deal Size : $9.9 million

                            Deal Type : Public Offering

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