[{"orgOrder":0,"company":"Roswell Park Comprehensive Cancer Center","sponsor":"Generate Biomedicines","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Collaboration","leadProduct":"CAR T-Cell Therapy","moa":"","graph1":"Oncology","graph2":"Discovery","graph3":"Roswell Park Comprehensive Cancer Center","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Roswell Park Comprehensive Cancer Center \/ Roswell Park Comprehensive Cancer Center","highestDevelopmentStatusID":"2","companyTruncated":"Roswell Park Comprehensive Cancer Center \/ Roswell Park Comprehensive Cancer Center"},{"orgOrder":0,"company":"Roswell Park Comprehensive Cancer Center","sponsor":"Aim ImmunoTech","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Oligonucleotide","year":"2022","type":"Inapplicable","leadProduct":"Rintatolimod","moa":"||TLR3","graph1":"Oncology","graph2":"Phase II","graph3":"Roswell Park Comprehensive Cancer Center","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Roswell Park Comprehensive Cancer Center \/ Roswell Park Comprehensive Cancer Center","highestDevelopmentStatusID":"8","companyTruncated":"Roswell Park Comprehensive Cancer Center \/ Roswell Park Comprehensive Cancer Center"},{"orgOrder":0,"company":"Roswell Park Comprehensive Cancer Center","sponsor":"Aim ImmunoTech","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Oligonucleotide","year":"2022","type":"Inapplicable","leadProduct":"Rintatolimod","moa":"||TLR3","graph1":"Oncology","graph2":"Phase II","graph3":"Roswell Park Comprehensive Cancer Center","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Roswell Park Comprehensive Cancer Center \/ Roswell Park Comprehensive Cancer Center","highestDevelopmentStatusID":"8","companyTruncated":"Roswell Park Comprehensive Cancer Center \/ Roswell Park Comprehensive Cancer Center"},{"orgOrder":0,"company":"Roswell Park Comprehensive Cancer Center","sponsor":"Aim ImmunoTech","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Oligonucleotide","year":"2022","type":"Inapplicable","leadProduct":"Rintatolimod","moa":"TLR3","graph1":"Oncology","graph2":"Phase II","graph3":"Roswell Park Comprehensive Cancer Center","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Roswell Park Comprehensive Cancer Center \/ Roswell Park Comprehensive Cancer Center","highestDevelopmentStatusID":"8","companyTruncated":"Roswell Park Comprehensive Cancer Center \/ Roswell Park Comprehensive Cancer Center"},{"orgOrder":0,"company":"Roswell Park Comprehensive Cancer Center","sponsor":"Aim ImmunoTech","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Oligonucleotide","year":"2022","type":"Inapplicable","leadProduct":"Rintatolimod","moa":"||TLR3","graph1":"Oncology","graph2":"Phase II","graph3":"Roswell Park Comprehensive Cancer Center","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Roswell Park Comprehensive Cancer Center \/ Roswell Park Comprehensive Cancer Center","highestDevelopmentStatusID":"8","companyTruncated":"Roswell Park Comprehensive Cancer Center \/ Roswell Park Comprehensive Cancer Center"},{"orgOrder":0,"company":"Roswell Park Comprehensive Cancer Center","sponsor":"The Division of Cancer Treatment and Diagnosis","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Oligonucleotide","year":"2020","type":"Funding","leadProduct":"Rintatolimod","moa":"TLR3","graph1":"Oncology","graph2":"Phase II","graph3":"Roswell Park Comprehensive Cancer Center","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Roswell Park Comprehensive Cancer Center \/ The Division of Cancer Treatment and Diagnosis","highestDevelopmentStatusID":"8","companyTruncated":"Roswell Park Comprehensive Cancer Center \/ The Division of Cancer Treatment and Diagnosis"}]

Find Clinical Drug Pipeline Developments & Deals by Roswell Park Comprehensive Cancer Center

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                          01

                          DCAT Week
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                          Details : The collaboration aims to discover and develop chimeric antigen receptor (CAR) T-cell therapies, and armoring technologies, for up to three oncology targets, including in ovarian cancer and other solid tumors.

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          November 01, 2023

                          Lead Product(s) : CAR T-Cell Therapy

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery

                          Recipient : Generate Biomedicines

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          02

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                          Details : Ampligen is AIM’s dsRNA product candidate being developed for globally important cancers, viral diseases and disorders of the immune system. Ampligen has demonstrated in the clinic the potential for standalone efficacy in a number of solid tumors.

                          Product Name : Ampligen

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          November 14, 2022

                          Lead Product(s) : Rintatolimod

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : Aim ImmunoTech

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

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                          Details : Ampligen (rintatolimod) is AIM’s dsRNA product candidate being developed for globally important cancers, viral diseases and disorders of the immune system.

                          Product Name : Ampligen

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          August 30, 2022

                          Lead Product(s) : Rintatolimod,Celecoxib,Interferon Alfa-2B

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Recipient : Aim ImmunoTech

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          DCAT Week
                          Not Confirmed
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                          Details : The data, from a small number of subjects, is extremely impressive for four out of six Ampligen plus pembrolizumab patients; three demonstrated disease stabilization and one showed a significant and dramatic rapid destruction of the tumor and metastasis.

                          Product Name : Ampligen

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          April 11, 2022

                          Lead Product(s) : Rintatolimod,Celecoxib,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : Aim ImmunoTech

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          DCAT Week
                          Not Confirmed
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                          Details : Primary endpoint of the study was met for Ampligen (rintatolimod), selective TLR3 ligand, evidenced by increased CD8a expression post-treatment (p=0.046), as a component of treatment for colorectal cancer metastatic to the liver.

                          Product Name : Ampligen

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          April 11, 2022

                          Lead Product(s) : Rintatolimod,Celecoxib,Recombinant Interferon Alfa-2B

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Recipient : Aim ImmunoTech

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          DCAT Week
                          Not Confirmed
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                          Details : Prestigious grant will fund 5 clinical trials in patients with 3 cancer types.

                          Product Name : Undisclosed

                          Product Type : Oligonucleotide

                          Upfront Cash : Undisclosed

                          April 06, 2020

                          Lead Product(s) : Rintatolimod

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : The Division of Cancer Treatment and Diagnosis

                          Deal Size : $14.5 million

                          Deal Type : Funding

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