Lead Product(s) : Ruxotemitide
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Verrica Announces Positive Results for Phase 2 Study of VP-315 in Basal Cell Carcinoma
Details : VP-315 (ruxotemitide)is a potential first-in-class oncolytic peptide to induce immunogenic cell death. It is under phase 2 clinical development for the treatment of Basal Cell Carcinoma.
Brand Name : VP-315
Molecule Type : Peptide
Upfront Cash : Not Applicable
August 14, 2024
Lead Product(s) : Ruxotemitide
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ruxotemitide
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Verrica Doses Last Patient in Phase 2 Study Of VP-315 for Skin Cancer
Details : VP-315 (ruxotemitide) is an oncolytic peptide immunotherapy in Phase 2, aiming to treat basal cell carcinoma by inducing immunogenic cell death.
Brand Name : VP-315
Molecule Type : Peptide
Upfront Cash : Not Applicable
January 05, 2024
Lead Product(s) : Ruxotemitide
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ruxotemitide
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : VP-315 (ruxotemitide, formerly known as LTX 315) is a potential first-in-class oncolytic peptide immunotherapy administered directly into a tumor to induce immunogenic cell death, which may offer a non-surgical option for patients suffering from skin can...
Brand Name : VP-315
Molecule Type : Peptide
Upfront Cash : Not Applicable
April 12, 2023
Lead Product(s) : Ruxotemitide
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ruxotemitide,Adoptive Cell Therapy
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The trial demonstrated that combination of LTX-315 and ACT is feasible and tolerable, and that CD4+ and CD8+ T cells can be expanded in vitro from STS that have been pretreated with the oncolytic molecule LTX-315.
Brand Name : LTX-315
Molecule Type : Peptide
Upfront Cash : Not Applicable
May 27, 2022
Lead Product(s) : Ruxotemitide,Adoptive Cell Therapy
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ruxotemitide,Tumour Infiltrating Lymphocytes
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lytix Biopharma to Present at the American Society of Clinical Oncology (ASCO) Annual Meeting
Details : LTX-315 is a potential first-in-class oncolytic molecule administered directly into a tumor to induce immunogenic cell death, which also has demonstrated positive tumor-specific immune cell responses in multi-indication Phase I/II oncology trials.
Brand Name : LTX-315
Molecule Type : Peptide
Upfront Cash : Not Applicable
April 28, 2022
Lead Product(s) : Ruxotemitide,Tumour Infiltrating Lymphocytes
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ruxotemitide
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Verrica Pharmaceuticals
Deal Size : $111.0 million
Deal Type : Licensing Agreement
Details : Verrica, has an exclusive license agreement with Lytix to develop and commercialize LTX-315 for skin cancer conditions. LTX-315 is a first-in-class oncolytic peptide derived from human lactoferrin, with potential lytic and immunostimulating activities.
Brand Name : LTX-315
Molecule Type : Peptide
Upfront Cash : Undisclosed
April 05, 2022
Lead Product(s) : Ruxotemitide
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Verrica Pharmaceuticals
Deal Size : $111.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Ruxotemitide
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : LTX-315, a potential first-in-class oncolytic peptide directly targets cancerous skin cells to induce an anti-tumor immune response, providing a potential alternative to surgery, for the treatment of basal cell carcinoma.
Brand Name : LTX-315
Molecule Type : Peptide
Upfront Cash : Not Applicable
April 05, 2022
Lead Product(s) : Ruxotemitide
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ruxotemitide
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Verrica Pharmaceuticals
Deal Size : $113.5 million
Deal Type : Licensing Agreement
Details : The licensing agreement is focused on developing and commercializing LTX-315 for dermatologic oncology indications. Verrica intends to focus initially on basal cell and squamous cell carcinomas as the lead indications for development.
Brand Name : LTX-315
Molecule Type : Peptide
Upfront Cash : Undisclosed
August 11, 2020
Lead Product(s) : Ruxotemitide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Verrica Pharmaceuticals
Deal Size : $113.5 million
Deal Type : Licensing Agreement
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