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Find Clinical Drug Pipeline Developments & Deals for Sabizabulin
Details :
VERU-111 (sabizabulin) is an oral, first-in-class small molecule that targets, binds to, and crosslinks the alpha and beta tubulin subunits of microtubules and intermediate filaments of cells resulting in disruption of inflammatory cell activities.
Details :
VERU-111 (sabizabulin) is an oral, first-in-class small molecule that targets, binds to, and crosslinks the alpha and beta tubulin subunits of microtubules and intermediate filaments of cells resulting in disruption of inflammatory cell activities.
Details :
VERU-111 (sabizabulin) prevented both the release of poxvirus from infected cells and the spread of poxvirus to healthy cells, reported in a preclinical in vitro study evaluating the effects of sabizabulin against prototypical poxvirus.
Details :
VERU-111 (sabizabulin) anti-inflammatory effects were previously reported in a preclinical septic shock mouse model with suppression of key cytokines responsible for severe acute respiratory distress syndrome (ARDS).
Details :
VERU-111 (sabizabulin) is an oral, first-in-class small molecule that targets, binds to, and crosslinks the alpha and beta tubulin subunits of microtubules and intermediate filaments of cells resulting in disruption of inflammatory cell activities.
Details :
VERU-111 (Sabizabulin) is an oral, first-in-class small molecule that targets, binds to, and crosslinks the alpha and beta tubulin subunits of microtubules and intermediate filaments of cells resulting in disruption of the cytoskeleton.
Details :
VERU-111 (sabizabulin) is microtubule disruptor with dual antiviral and anti-inflammatory activities. In post hoc analysis, in COVID-19 patients who had at least one comorbidity and,required oxygen, baseline characteristics were similar between sabizabul...
Details :
Treatment with Sabizabulin (VERU-111), an oral, first-in-class, new chemical entity, microtubule disruptor that has dual anti-inflammatory and antiviral properties, resulted in a significant 55.2% relative reduction in deaths compared to placebo.
Details :
Treatment with VERU-111 (sabizabulin) an oral, first-in-class, new chemical entity, microtubule disruptor that has dual anti-inflammatory and antiviral properties, resulted in clinically meaningful and statistically significant 55.2% relative reduction c...
Details :
Treatment with VERU-111 (sabizabulin) an oral, first-in-class, new chemical entity, microtubule disruptor that has dual anti-inflammatory and antiviral properties, resulted in a clinically meaningful and statistically significant 55.2% relative reduction...
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