Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Salinomycin
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : HSB-1216, is a novel and potent inducer of a powerful mechanism involving iron-mediated cell death. It is an emerging new anti-cancer mechanism, resulting in iron mediated cell death (IMCD) of drug resistant cancers.
Product Name : HSB-1216
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 04, 2023
Lead Product(s) : Salinomycin
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Salinomycin
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Thinkequity
Deal Size : $2.6 million
Deal Type : Public Offering
Hillstream BioPharma Announces Pricing of Public Offering
Details : The Company intends to use the net proceeds from the offering for the advancement of HSB-1216, a novel and potent inducer of a powerful mechanism involving iron-mediated cell death, and the development of other product candidates in the Company’s pipel...
Product Name : HSB-1216
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
April 27, 2023
Lead Product(s) : Salinomycin
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Thinkequity
Deal Size : $2.6 million
Deal Type : Public Offering
Lead Product(s) : Salinomycin
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Hillstream BioPharma
Deal Size : Undisclosed
Deal Type : Agreement
Details : Under the agreement, OncoBay will provide comprehensive clinical and regulatory support for the clinical development program for Hillstream's lead drug HSB-1216, which targets ferroptosis, an emerging new anti-cancer mechanism, resulting in IMCD of drug ...
Product Name : HSB-1216
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
April 13, 2023
Lead Product(s) : Salinomycin
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Hillstream BioPharma
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Salinomycin
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Thinkequity
Deal Size : $2.6 million
Deal Type : Public Offering
Hillstream BioPharma Announces Closing of Public Offering of Common Stock
Details : The Company intends to use the net proceeds for the advancement of its lead drug candidate HSB-1216, which targets ferroptosis, an emerging new anti-cancer mechanism, and the development of other product candidates in the Company’s pipeline.
Product Name : HSB-1216
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
February 05, 2023
Lead Product(s) : Salinomycin
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Thinkequity
Deal Size : $2.6 million
Deal Type : Public Offering
Lead Product(s) : Salinomycin
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Dana-Farber Cancer Institute
Deal Size : Undisclosed
Deal Type : Agreement
Details : Dana-Farber has granted under an exclusive option agreement to Hillstream Biopharma Inc., to develop anti-MUC1-C antibodies to selectively deliver Hillstream’s Quatramer-based lead candidate HSB-1216 targeting CSC by the induction of ferroptosis.
Product Name : HSB-1216
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
January 31, 2023
Lead Product(s) : Salinomycin
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Dana-Farber Cancer Institute
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Salinomycin
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Thinkequity
Deal Size : $15.0 million
Deal Type : Public Offering
Hillstream BioPharma Announces Pricing of Initial Public Offering
Details : The net proceeds from the initial public offering will be used to advance the Company’s product candidate HSB-1216 through pre-clinical activities, completion of Phase 1 studies and manufacturing, to advance the Company’s candidate HSB-888 through pr...
Product Name : HSB-1216
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
November 01, 2022
Lead Product(s) : Salinomycin
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Thinkequity
Deal Size : $15.0 million
Deal Type : Public Offering
Lead Product(s) : Salinomycin,Undisclosed
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Sapien Biosciences
Deal Size : Undisclosed
Deal Type : Collaboration
Hillstream BioPharma Announces Collaboration with Sapien Biosciences in Cancer Treatments
Details : The active drug in HSB-1216 was found to be efficacious in a clinical pilot study in Germany in devastating cancers, including triple negative breast cancer and epithelial carcinomas. Hillstream intends to start a clinical study with HSB-1216 in 2022.
Product Name : HSB-1216
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
June 27, 2022
Lead Product(s) : Salinomycin,Undisclosed
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Sapien Biosciences
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Salinomycin
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : HSB-1216, novel ferroptosis inducer against solid tumors has been granted an Orphan Drug Designation for significant need for patients with devastating disease for the treatment of uveal melanoma by the US FDA.
Product Name : HSB-1216
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 16, 2022
Lead Product(s) : Salinomycin
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Salinomycin
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : HSB-1216, an IMCD modulator active moiety in clinical pilot study produced a 71% response rate and efficacy against devastating cancers, including TNBC and epithelial carcinomas also targets solid tumors as a ferroptosis-inducing agent.
Product Name : HSB-1216
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 03, 2022
Lead Product(s) : Salinomycin
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Salinomycin
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Hillstream BioPharma Presentations at 2020 AACR Virtual Annual Meeting II
Details : Abstracts highlight data from HSB-1216 (Salinomycin QUATRAMER™) in small cell lung cancer and triple negative breast cancer.
Product Name : HSB-1216
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 19, 2020
Lead Product(s) : Salinomycin
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable